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3. Anesthesiology

  Anesthesiology curriculum 
===========================

 Conquer Anesthesiology Boards with Calm Confidence

      Core   Advanced   

    Anesthesiology Core Pathway

###  Basic Sciences 

   2,168 questions   

####  Anatomy for anesthesia (airway, neuraxial, vascular, regional) 

   50   

         - Neuraxial anatomy and dermatomes  

    - Dermatome and block height assessment   4
    - Meninges and CSF spaces   4
    - Vertebral column and ligamentous structures   4
- Peripheral nerve anatomy (regional anesthesia essentials)  

    - Brachial plexus overview   5
    - Lower limb plexuses   5
    - Truncal blocks anatomy   5
- Upper airway anatomy and airway assessment landmarks  

    - Airway examination correlates   5
    - Nasal and oral cavity anatomy   4
    - Pharynx and larynx anatomy   5
- Vascular access anatomy  

    - Arterial access anatomy   4
    - Central venous anatomy   5

####  Anatomy, Surgical Anatomy &amp; Pelvic Support 

   70   

  Gross and applied anatomy relevant to obstetrics, gynecology, pelvic surgery, continence/prolapse, a...

         - Adnexa and tubo-ovarian anatomy  

    - Broad ligament spaces and adnexal torsion anatomy   2
    - Fallopian tube segments and function   3
    - Ovary—blood supply and surgical implications   2
    - Parametrium and ureteric course   2
    - Pelvic sidewall landmarks   3
- Bony pelvis, pelvic diameters, and obstetric biomechanics  

    - Anatomy relevant to operative vaginal birth   3
    - Maternal pelvis shapes and relevance   3
    - Mechanisms of labor and fetal head molding   3
    - Pelvic floor interaction with birth   3
    - Pelvimetry concepts and clinical utility   2
- Breast anatomy and lactation-relevant structures  

    - Breast ducts, lobules, and lymphatics   3
    - Breast imaging anatomy correlation   2
    - Nipple–areolar complex anatomy   3
    - Physiology-anatomy interface in lactation   3
    - Surgical anatomy (duct excision, abscess drainage) basics   3
- Pelvic floor, continence mechanisms and anorectal anatomy  

    - Anal sphincter complex   4
    - Levator ani and fascial supports   3
    - Lower urinary tract anatomy   2
    - Neurovascular anatomy relevant to pelvic pain   3
    - Perineum and episiotomy landmarks   3
- Uterus, cervix, vagina and vulva—applied anatomy  

    - Cervical anatomy and transformation zone   2
    - Lymphatic drainage of lower genital tract   3
    - Uterine layers and supporting ligaments   3
    - Vaginal anatomy and fornices   3
    - Vulvar anatomy   4

####  Applied Anatomy for Emergency Care 

   117   

  Regional anatomy relevant to resuscitation, procedures, and time-critical diagnosis.

         - Abdominal and pelvic anatomy for acute abdomen  

    - Appendix, bowel, mesentery   5
    - Genitourinary anatomy   5
    - Hepatobiliary and pancreatic anatomy   5
    - Pelvic anatomy and hemorrhage   3
    - Peritoneal spaces and referred pain   5
- Airway, neck, and upper aerodigestive anatomy  

    - Airway edema/obstruction implications   5
    - Larynx and trachea   4
    - Neck vascular/nerve structures   4
    - Surgical airway anatomy (foundational)   4
    - Upper airway landmarks   5
- Musculoskeletal compartments and vascular anatomy  

    - Compartment syndrome anatomy   4
    - Fracture patterns and growth plates (intro)   5
    - Major joints: stability and reduction basics   5
    - Ultrasound-relevant vascular anatomy   5
    - Vascular anatomy for hemorrhage control   5
- Neuroanatomy and spinal anatomy for EM  

    - Cerebral vascular territories (exam-relevant)   5
    - Intracranial compartments and herniation   4
    - Ocular and orbital anatomy   5
    - Peripheral nerve anatomy for injuries/blocks   5
    - Spinal cord/nerve root anatomy   5
- Thoracic anatomy and pleura  

    - Chest wall, ribs, diaphragm   5
    - Mediastinum and great vessels   6
    - Pericardium and cardiac anatomy basics   5
    - Pleural spaces and lung lobes   5
    - Procedural anatomy (thoracic)   3

####  Biochemistry, Metabolism &amp; Nutrition 

   37   

  Core metabolic pathways, organ metabolism, and clinically important deficiencies/excesses.

         - Carbohydrate and lipid metabolism (clinically applied)  

    - Glycolysis/gluconeogenesis concepts   3
    - Inborn errors (overview)   4
    - Lipid metabolism   3
    - Obesity and insulin resistance   2
- Micronutrients and deficiency syndromes  

    - Fat-soluble vitamins   3
    - Refeeding syndrome   3
    - Trace elements   3
    - Water-soluble vitamins   3
- Protein metabolism and liver synthetic function  

    - Albumin and oncotic pressure   4
    - Amino acid metabolism   4
    - Bilirubin metabolism   3
    - Coagulation factors synthesis   2

####  Cardiovascular physiology and measurement 

   71   

         - Cardiac electrophysiology and ECG basics  

    - Arrhythmia mechanisms (exam core)   5
    - Cardiac action potentials   4
    - Conduction system anatomy/physiology   5
    - Defibrillation/cardioversion principles   5
    - ECG interpretation for anesthesia   5
- Cardiac pump function and determinants of CO  

    - Autonomic control of circulation   5
    - Determinants of SVR and MAP   4
    - Frank–Starling physiology   5
    - Myocardial oxygen supply/demand   5
    - Pressure–volume concepts   6
    - Shock physiology (core principles)   5
- Oxygen transport and hemodynamic oxygenation metrics  

    - Hemoglobin–oxygen dissociation curve   4
    - Microcirculation basics   5
    - Oxygen consumption and extraction   4
    - Oxygen content and delivery   4

####  Cellular &amp; Molecular Biology 

   43   

  Core cellular structure/function and signaling relevant to disease mechanisms and therapeutics.

         - Cell structure, organelles, and trafficking  

    - Cell cycle, apoptosis, necrosis   3
    - Cell–cell junctions and extracellular matrix   4
    - Membrane structure &amp; transport   4
    - Organelles and key functions   4
- Oncogenesis fundamentals  

    - Cancer immunology (intro)   3
    - Carcinogenesis &amp; exposures   3
    - Hallmarks of cancer (board-level)   3
    - Tumor suppressors and oncogenes   4
- Signal transduction &amp; second messengers  

    - Inflammation signaling   4
    - Pharmacologic implications   3
    - Receptor classes   4
    - Second messengers   4

####  Clinical epidemiology, biostatistics, and evidence-based practice 

   55   

  Board-relevant study design, diagnostic testing performance, screening, clinical decision-making, an...

         - Basic statistics interpretation (board level)  

    - Confidence intervals   3
    - Hypothesis testing and p-values   3
    - Inter-rater reliability and kappa   2
    - Measures of central tendency and spread   3
    - Regression basics (conceptual)   3
- Diagnostic test characteristics  

    - Decision rules (e.g., PECARN concept)   3
    - Interpreting lab reference ranges in pediatrics   3
    - Likelihood ratios and post-test probability   2
    - ROC curves and thresholds (conceptual)   2
    - Sensitivity, specificity, predictive values   3
- Screening principles and prevention evidence  

    - Clinical practice guidelines (CPGs)   3
    - Criteria for screening programs   4
    - Ethics in evidence application   3
    - Number needed to treat/harm   3
    - Public health measures and outbreak basics   2
- Study designs and hierarchy of evidence  

    - Diagnostic test studies   3
    - Interventional studies (RCTs)   3
    - Observational studies (cohort, case-control, cross-sectional)   2
    - Quality improvement vs research (distinction)   3
    - Systematic reviews and meta-analyses   2

####  Clinical pharmacology and therapeutics (core) 

   76   

  Weight-based dosing, pediatric pharmacokinetics/dynamics, antimicrobial fundamentals, common drug cl...

         - Analgesia, sedation, and peri-procedural medications  

    - Common agents and adverse effects   4
    - Local anesthetics and toxicity   4
    - Non-opioid analgesics   3
    - Opioids and respiratory depression risk   3
    - Procedural sedation core concepts   4
- Antimicrobial classes and selection (foundational)  

    - Aminoglycosides and nephro/ototoxicity   2
    - Antiviral/antifungal overview (core)   3
    - Beta-lactams and cephalosporins   4
    - Macrolides and atypical coverage   3
    - MRSA agents (clindamycin, TMP-SMX, vancomycin, linezolid)   2
- Common pediatric chronic medication classes (core board level)  

    - Antiepileptic drugs overview   3
    - Asthma/allergy pharmacotherapy basics   4
    - Cardiac medications basics   3
    - Endocrine medications basics   3
    - Psychotropic basics (overview)   3
- Pediatric dosing principles and medication safety  

    - Adverse drug reaction types   3
    - Medication reconciliation and error prevention   3
    - Routes of administration and bioavailability   3
    - Therapeutic drug monitoring (TDM) basics   3
    - Weight-based dosing and dose limits   2
- Pediatric pharmacokinetics and pharmacodynamics  

    - Absorption differences by age   3
    - Distribution (body water/fat, protein binding)   3
    - Elimination (renal maturation)   3
    - Metabolism (hepatic enzymes)   2
    - Pharmacogenomics basics (board overview)   3

####  Core anesthesia pharmacology (drug classes) 

   95   

         - Cardiovascular drugs commonly used in anesthesia  

    - Antiarrhythmics (core familiarity)   4
    - Antihypertensives and antianginals   5
    - Vasopressors and inotropes   6
- Inhalational anesthetics  

    - MAC and factors affecting MAC   6
    - Organ effects and toxicity   6
    - Special phenomena   5
    - Uptake and distribution   4
- Intravenous induction agents and sedatives  

    - Benzodiazepines   4
    - Dexmedetomidine and alpha-2 agonists   4
    - Etomidate   4
    - Ketamine   5
    - Propofol   5
- Neuromuscular blockers and reversal agents  

    - Depolarizing blockade (succinylcholine)   4
    - Monitoring and reversal   4
    - NMJ physiology relevant to blockade   5
    - Nondepolarizing blockade   4
- Opioids and adjunct analgesics  

    - Adjuvant analgesics (exam-relevant)   4
    - Common IV opioids in anesthesia   5
    - Non-opioid analgesics (core)   5
    - Opioid receptor pharmacology   6

####  Core Physiology and Pathophysiology 

   147   

  High-yield physiologic principles that underpin ED presentation patterns and first-line therapy.

         - Acid–base physiology and interpretation  

    - Metabolic acidosis   4
    - Metabolic alkalosis   5
    - Osmolar gap and toxin clues   4
    - Respiratory acidosis/alkalosis   5
    - Systematic interpretation approach   5
- Inflammation, immunity, and sepsis pathobiology  

    - Anaphylaxis physiology   5
    - Coagulation-inflammation interface   5
    - Fever physiology   4
    - Host response to infection   6
    - Vaccines, immunization status, and ED relevance   5
- Neurophysiology of consciousness, seizure, and delirium  

    - Delirium and encephalopathy mechanisms   3
    - Raised ICP physiology   4
    - Reticular activating system and coma basics   6
    - Seizure generation and termination (conceptual)   4
    - Temperature and CNS function   5
- Oxygen delivery, shock physiology, and perfusion  

    - Determinants of oxygen delivery   4
    - Fluid responsiveness and endpoints   5
    - Reperfusion and resuscitation complications   5
    - Shock classification and physiology   6
    - Vasopressors/inotropes physiology   6
- Renal physiology and electrolyte homeostasis  

    - Acute kidney injury pathophysiology   6
    - Calcium, magnesium, phosphate physiology   6
    - Diuretics and renal pharmacodynamics (intro)   5
    - Potassium physiology and membrane excitability   6
    - Sodium and water balance   5
- Respiratory mechanics and gas exchange  

    - Acid-base interplay in respiratory disease   4
    - Hypoxemia mechanisms   5
    - Ventilation strategy principles (intro)   5
    - Ventilation vs oxygenation concepts   5
    - Work of breathing and fatigue   4

####  Developmental physiology and anatomy 

   103   

  Age-dependent structure and function across fetal, neonatal, infant, child, and adolescent stages re...

         - GI, hepatic, and pancreatic developmental physiology  

    - Bilirubin metabolism   2
    - Feeding physiology and gastric emptying   4
    - Gut microbiome concepts (board-relevant)   3
    - Liver synthetic function and vitamin K   3
    - Pancreatic function maturation   2
- Neurodevelopmental physiology (foundation)  

    - Brain development timing and vulnerability   3
    - Intracranial pressure basics   3
    - Pain pathways and developmental differences   3
    - Seizure physiology overview   3
    - Sleep physiology across development   3
- Fetal-to-neonatal transition physiology  

    - Cardiovascular transition and shunts   3
    - Neonatal glucose homeostasis   3
    - Placental to pulmonary gas exchange transition   3
    - Respiratory adaptation   3
    - Thermoregulation at birth   3
- Hematopoiesis and pediatric hemostasis basics  

    - Age-based CBC norms   3
    - Coagulation and bleeding evaluation foundations   3
    - Hemoglobin switching and oxygen affinity   3
    - Iron metabolism and erythropoiesis   3
    - Transfusion medicine basics   4
- Pediatric cardiovascular physiology basics  

    - Blood pressure norms and perfusion   3
    - Cardiac output determinants by age   2
    - Congenital heart physiology patterns   3
    - Oxygen delivery and consumption   2
    - Shock physiology overview   3
- Pediatric respiratory mechanics basics  

    - Age-dependent airway anatomy   3
    - Basic blood gas interpretation   4
    - Pulmonary defense mechanisms   3
    - Ventilation-perfusion relationships   3
    - Work of breathing and fatigue   2
- Renal maturation and fluid homeostasis  

    - Acid handling and bicarbonate physiology   3
    - Neonatal electrolyte vulnerabilities   3
    - Neonatal renal function and GFR maturation   3
    - Urine output norms and interpretation   3
    - Water balance regulation   3

####  Embryology, Fetal Development &amp; Congenital Anomalies 

   42   

  Embryology and developmental physiology underpinning congenital anomalies and reproductive tract dis...

         - Gametogenesis, fertilization, implantation and early placentation  

    - Amniotic fluid development and regulation   3
    - Fertilization and early embryo development   2
    - Implantation physiology and abnormal implantation   3
    - Oogenesis and spermatogenesis essentials   3
    - Placental development and cord formation   3
- Müllerian development and reproductive tract anomalies  

    - Cervical insufficiency developmental considerations   2
    - Congenital anomalies—screening principles   3
    - Müllerian duct fusion and canalization   3
    - Ovarian and testicular differentiation   3
    - Urogenital sinus development   2
- Organogenesis and teratology timing  

    - Common teratogens and patterns   5
    - Congenital infection pathogenesis (TORCH concept)   3
    - Critical periods of development   2
    - Fetal growth regulation   2
    - Placental transfer and fetal drug exposure   3

####  Emergency Pharmacology and Therapeutics 

   117   

  PK/PD and emergency drug classes frequently tested and used in ED resuscitation and symptom control.

         - Analgesia in emergency medicine  

    - Ketamine for analgesia   3
    - Non-opioid analgesics   5
    - Opioid pharmacology and safe prescribing   6
    - Pain syndromes and multimodal strategy   4
    - Regional anesthesia principles (intro)   5
- Antimicrobials and stewardship essentials  

    - Allergy, anaphylaxis, and cross-reactivity   5
    - Antibiotic adverse effects   5
    - Antiviral/antifungal (board-level)   5
    - Empiric antibiotic selection principles   4
    - High-yield ED syndromes (empiric)   4
- Cardiovascular and vasoactive medications  

    - Antiarrhythmics and rate control   5
    - Antihypertensives in emergencies   5
    - Antithrombotics and reperfusion adjuncts   6
    - Reversal agents (core overview)   5
    - Vasopressors/inotropes   5
- Pharmacokinetics/pharmacodynamics in the ED  

    - Absorption, distribution, metabolism, elimination   4
    - Drug interactions and adverse drug events   5
    - Medication safety principles   5
    - Onset/offset and context-sensitive half-time   5
    - Pharmacogenomics and variability (board-level)   3
- Sedation, induction agents, and anxiolysis  

    - Benzodiazepines   5
    - Dexmedetomidine (board-level overview)   4
    - Ketamine dissociation   4
    - Procedural sedation safety   5
    - Propofol and etomidate basics   5

####  Epidemiology, Biostatistics &amp; Evidence-Based Medicine 

   45   

  Study design, bias, test performance, causality, and applying evidence to patient care.

         - Clinical guidelines and evidence synthesis  

    - Ethics in research   3
    - GRADE and strength of recommendation   3
    - Implementation and de-implementation   3
    - Systematic reviews/meta-analyses   3
- Diagnostic test interpretation  

    - Bayesian reasoning   2
    - Core measures   3
    - ROC curves and thresholds   2
    - Screening principles   3
- Study design and validity  

    - Bias and confounding   3
    - Causality and inference   3
    - Interventional trials   3
    - Observational designs   4
- Treatment effects and risk  

    - Decision analysis basics   3
    - Effect size measures   2
    - Heterogeneity and subgroup analyses   3
    - Time-to-event analysis   2

####  Fluids, electrolytes, and acid–base 

   83   

  Core calculations and physiologic reasoning for pediatric fluid management, electrolyte abnormalitie...

         - Calcium, magnesium, and phosphate disorders  

    - Hypercalcemia differential and initial workup   2
    - Hypomagnesemia and refractory hypokalemia/hypocalcemia   2
    - Neonatal hypocalcemia (early/late)   3
    - Phosphate abnormalities (refeeding, DKA)   3
    - QT prolongation and electrolyte-related arrhythmias   3
- Acid–base disorders and interpretation  

    - Bicarbonate therapy: indications and risks   4
    - Metabolic acidosis differential (high vs normal anion gap)   4
    - Metabolic alkalosis differential   3
    - Respiratory acidosis/alkalosis scenarios   3
    - Stepwise blood gas interpretation   3
- Hypernatremia in children  

    - Central diabetes insipidus management   3
    - Correction strategy and monitoring   3
    - Etiologies and diagnostic approach   3
    - Nephrogenic diabetes insipidus basics   2
    - Neurologic complications of dysnatremias   2
- Hyponatremia in children  

    - Acute symptomatic hyponatremia management   3
    - Classification by volume status   3
    - Osmotic demyelination risk   2
    - Pseudohyponatremia and lab pitfalls   3
    - SIADH approach   3
- Maintenance fluids and dehydration management  

    - Assessment of dehydration severity   3
    - Hypernatremic dehydration   2
    - IV fluid bolus and deficit replacement   3
    - Maintenance fluid calculation and composition   3
    - Oral rehydration therapy (ORT)   2
- Potassium disorders (hypo/hyperkalemia)  

    - Hyperkalemia emergency management   3
    - Hyperkalemia recognition and ECG changes   3
    - Hypokalemia causes and evaluation   2
    - Renal tubular disorders related to potassium   3
    - Replacement strategies and safety   2

####  Genetics &amp; Genomics 

   31   

  Mendelian and complex genetics, genomic medicine, and clinically actionable variants.

         - Complex traits and gene–environment interaction  

    - Epigenetics   3
    - Microbiome (board-level concepts)   2
    - Polygenic risk concepts   3
    - Somatic mosaicism &amp; clonal hematopoiesis   2
- Genomic testing in clinical practice  

    - Ethical issues   2
    - Pharmacogenomics   3
    - Testing modalities   2
    - Variant interpretation   3
- Mendelian inheritance and risk  

    - Autosomal dominant patterns   3
    - Autosomal recessive patterns   3
    - Mitochondrial inheritance   2
    - X-linked inheritance   3

####  Genetics and metabolism (introductory) 

   57   

  Foundations of inheritance, genetic testing, dysmorphology approach, and introductory inborn error r...

         - Dysmorphology and congenital anomaly approach  

    - Approach to a dysmorphic child   3
    - Common genetic syndromes (core list)   3
    - Referral and multidisciplinary care   2
    - Syndromic vs sequence vs association concepts   3
    - Teratology basics   4
- Inborn errors: pattern recognition (intro)  

    - Hypoglycemia patterns and ketones   3
    - Lactic acidosis and mitochondrial disease overview   2
    - Metabolic acidosis and hyperammonemia patterns   3
    - Newborn with lethargy/vomiting after feeds   3
    - Recurrent rhabdomyolysis and exercise intolerance   2
- Genetic testing modalities and indications  

    - Ethical considerations in pediatric genetics   2
    - Karyotype, microarray, and targeted panels   3
    - Newborn screening follow-up basics   3
    - Prenatal testing concepts (board-level)   2
    - Single-gene sequencing and exome/genome sequencing   3
- Patterns of inheritance and pedigree interpretation  

    - Autosomal dominant/recessive patterns   3
    - Chromosomal abnormalities overview   4
    - De novo variants and recurrence risk   3
    - Multifactorial inheritance and risk   3
    - X-linked and mitochondrial inheritance   3

####  Genetics, Immunology, Hematology &amp; Teratology 

   65   

  Genetic principles, prenatal screening/diagnosis frameworks, immunohematology (Rh), and teratology r...

         - Genetic inheritance and counseling fundamentals  

    - Carrier screening concepts   4
    - Chromosomal abnormalities and mechanisms   4
    - Consanguinity and risk quantification basics   2
    - Genetic test ethics and informed consent   3
    - Patterns of inheritance   4
- Immunohematology and alloimmunization  

    - Fetal anemia assessment principles   2
    - Non-D antibodies and clinical relevance   3
    - RhD immunization prevention   3
    - Thrombophilia concepts   3
    - Transfusion medicine basics in OB   4
- Prenatal screening and diagnostic testing  

    - Aneuploidy screening modalities   3
    - Diagnostic procedures principles   3
    - Neural tube defect screening and diagnosis   4
    - Non-immune hydrops framework   3
    - Screening test performance interpretation   3
- Teratology and environmental exposures  

    - Infections as teratogens (TORCH)   4
    - Medication risk frameworks   3
    - Occupational/environmental hazards   4
    - Radiation exposure in pregnancy   3
    - Substance use and fetal effects   3

####  Hematology, Transfusion, and Evidence-Based Medicine 

   94   

  Coagulation, transfusion science, and biostatistics/EBM essentials commonly assessed in EM training...

         - EBM in practice: guidelines, pathways, and stewardship  

    - Antimicrobial and imaging stewardship   4
    - Applying guidelines safely   3
    - Critical incident literature appraisal (M&amp;M style)   4
    - Quality metrics vs patient-centered outcomes   4
    - Screening and prevention in ED context   5
- Biostatistics and clinical epidemiology for EM  

    - Bias, confounding, and validity   4
    - Clinical prediction rules and implementation   6
    - Diagnostic test performance   5
    - Measures of effect and uncertainty   4
    - Study designs and hierarchy of evidence   5
- Hemostasis and coagulation fundamentals  

    - Bleeding risk stratification (conceptual)   4
    - Coagulopathies in the ED   6
    - Heparin/DOAC physiology and lab interpretation   5
    - Primary vs secondary hemostasis   6
    - Thrombosis physiology   5
- Transfusion medicine and massive hemorrhage basics  

    - Blood products and indications   5
    - Hemolysis and anemia emergencies   5
    - Massive transfusion principles   5
    - Rh/alloimmunization principles (ED-relevant)   4
    - Transfusion reactions   5

####  Immunology &amp; Inflammation 

   36   

  Innate/adaptive immunity, hypersensitivity, autoimmunity, immunodeficiency, and transplant fundament...

         - Adaptive immunity  

    - B cell biology and antibodies   4
    - Hypersensitivity reactions   3
    - T cell biology   3
    - Vaccinology principles   2
- Autoimmunity and tolerance  

    - Central and peripheral tolerance   3
    - Immunodeficiency overview   3
    - Systemic autoimmune disease mechanisms   3
    - Transplant immunology (intro)   3
- Innate immunity and inflammation  

    - Complement system   3
    - Inflammation resolution   3
    - Pattern recognition and cytokines   3
    - Phagocytes and granulomatous inflammation   3

####  Immunology, inflammation, and allergy foundations 

   84   

  Fundamental immune mechanisms, hypersensitivity, primary immunodeficiency red flags, and vaccine imm...

         - Autoimmunity and immune dysregulation fundamentals  

    - Autoantibodies and immune tolerance concepts   3
    - Autoinflammatory syndromes (intro)   4
    - Cytokine storm/HLH conceptual bridge   3
    - Cytopenias and autoimmune disease links   3
    - Immune-mediated kidney and skin disease examples   3
- Hypersensitivity and allergic disease mechanisms  

    - Atopic disease spectrum   4
    - Drug allergy vs intolerance   3
    - Food allergy mechanisms and tolerance   4
    - Type I (IgE-mediated) reactions   4
    - Type II/III/IV hypersensitivity examples   4
- Innate and adaptive immune system basics  

    - Adaptive immunity components   4
    - Complement system basics   3
    - Inflammation resolution and chronic inflammation   3
    - Innate immunity components   4
    - Mucosal immunity and IgA   3
- Primary immunodeficiency (PID) overview and red flags  

    - Basic lab evaluation of immune function   3
    - Clinical warning signs and patterns   3
    - Immunization considerations in immunocompromise   3
    - Secondary immunodeficiency causes   3
    - T-cell vs B-cell vs phagocyte vs complement defects   4
- Vaccine immunology foundations  

    - Active vs passive immunity principles   3
    - Adjuvants and immunogenicity   3
    - Herd immunity and population impact (exam framing)   4
    - Live attenuated vs inactivated vaccines   3
    - Vaccine adverse events and safety systems   3

####  Maternal–Fetal Physiology, Placenta &amp; Parturition 

   55   

  Pregnancy adaptations, uteroplacental unit physiology, and labor physiology essential for safe obste...

         - Maternal cardiovascular and hemodynamic adaptations  

    - Blood pressure physiology across trimesters   3
    - Changes in blood volume, CO, SVR   3
    - Coagulation physiology (hypercoagulability)   2
    - Postpartum hemodynamic shifts   3
    - Uterine blood flow physiology   2
- Placental function, transport, and endocrine activity  

    - Amniotic fluid dynamics   3
    - Maternal–fetal immunology   2
    - Placental endocrine hormones   3
    - Placental transport mechanisms   3
    - Umbilical and fetal circulation physiology   3
- Respiratory, renal, and acid–base physiology in pregnancy  

    - GI/hepatic adaptations   3
    - Hematologic adaptations beyond coagulation   3
    - Renal changes and lab interpretation   3
    - Thermoregulation and skin changes   3
    - Ventilatory changes and ABG interpretation   2
- Uterine contractility and cervical remodeling  

    - Cervical ripening mechanisms   3
    - Lactation physiology   3
    - Myometrial excitation–contraction coupling   2
    - Postpartum uterine involution   2
    - Stages of labor physiology   4

####  Neurophysiology, autonomics, and thermoregulation 

   43   

         - Autonomic nervous system and reflexes  

    - Autonomic failure and dysautonomia   6
    - Key perioperative reflexes   5
    - Sympathetic vs parasympathetic physiology   5
- Cerebral blood flow and intracranial dynamics  

    - CBF regulation   5
    - CSF production and drainage   4
    - ICP physiology   4
- Thermoregulation and perioperative hypothermia  

    - Anesthesia effects on temperature   5
    - Complications of hypothermia   4
    - Normal thermoregulatory control   5

####  Nutrition, growth biology, and metabolic fundamentals 

   76   

  Core pediatric nutrition and metabolism including breastfeeding, micronutrients, malnutrition, obesi...

         - Energy metabolism and common IEM overview (intro)  

    - Acute metabolic decompensation first steps   2
    - Basic pathways (glycogen, FAO, urea cycle)   4
    - Hypoglycemia differential by age   3
    - Newborn screen concept and limitations   2
    - When to refer for metabolic/genetic evaluation   3
- Failure to thrive (FTT) and malnutrition  

    - Definitions and anthropometric assessment   3
    - Differential diagnosis framework   3
    - Initial evaluation and targeted testing   3
    - Multidisciplinary management and safeguarding interface   3
    - Nutritional rehabilitation   3
- Infant feeding (breastfeeding and formula)  

    - Breast milk composition and benefits (exam framing)   2
    - Complementary feeding and allergen introduction   4
    - Feeding difficulties and red flags   3
    - Formula types and indications   4
    - Lactation management basics   3
- Micronutrients and deficiency states  

    - Iodine and thyroid development   3
    - Iron deficiency and anemia prevention   2
    - Vitamin A, E, K deficiencies (board-relevant)   4
    - Vitamin D and calcium   4
    - Zinc and trace elements   3
- Pediatric obesity and metabolic risk  

    - BMI classification and staging   4
    - Lifestyle intervention fundamentals   2
    - Metabolic syndrome and NAFLD overview   3
    - Obesity pharmacotherapy and bariatric basics (board overview)   3
    - Weight stigma and counseling skills   3

####  Pathology &amp; General Pathophysiology 

   35   

  General injury, repair, vascular pathology, thrombosis, and systemic responses to illness.

         - Cell injury and adaptation  

    - Amyloidosis (overview)   3
    - Edema and effusions pathophysiology   3
    - Inflammation and repair   3
    - Reversible vs irreversible injury   3
- Fever, SIRS, and sepsis biology  

    - Biomarkers (concepts)   3
    - Cytokine-mediated shock   3
    - Organ dysfunction mechanisms   3
    - Stress response and endocrine changes   3
- Hemostasis and thrombosis (mechanisms)  

    - Atherosclerosis &amp; aneurysm pathophysiology   3
    - Coagulation cascade (clinical interpretation)   3
    - Platelet biology   2
    - Thrombosis and embolism   3

####  Pathology, Neoplasia, and Breast Pathology Foundations 

   73   

  Core gynecologic and obstetric pathology and tumor biology underpinning screening, diagnosis, and in...

         - Inflammation, infection, and tissue response basics  

    - Acute vs chronic inflammation patterns   2
    - Necrosis patterns relevant to OB-GYN   3
    - Pathology specimen handling basics   3
    - Thrombosis and embolism concepts   3
    - Wound healing and scar formation   3
- Breast pathology foundations for OB-GYN  

    - Benign breast disease   3
    - Breast cancer basics for generalists   3
    - Breast screening and pathology correlation   4
    - High-risk lesions overview   3
    - Lactation-related breast conditions   3
- Cervical pathology and HPV-mediated disease  

    - CIN/HSIL/LSIL pathologic correlates   3
    - Cytology and histology interpretation basics   3
    - HPV biology and carcinogenesis   3
    - Invasive cervical cancer—histology overview   3
    - Vaginal/vulvar intraepithelial lesions basics   3
- Endometrial pathology and AUB foundations  

    - Benign uterine pathology   3
    - Endometrial carcinoma basics (Type 1 vs Type 2)   3
    - Endometrial hyperplasia classification concepts   2
    - Gestational endometrium and retained products concepts   3
    - Uterine sarcomas overview   3
- Ovarian, tubal, and peritoneal tumors—foundations  

    - Borderline tumors concepts   2
    - Fallopian tube origin hypothesis for HGSC   3
    - GTD pathology overview   3
    - Ovarian tumor classification overview   3
    - Tumor markers basics   3

####  Pharmacology fundamentals (PK/PD and drug handling) 

   61   

         - Pharmacodynamics and receptor theory  

    - Dose–response relationships   4
    - Drug interactions   5
    - Pharmacogenomics (core testables)   5
    - Receptor types and signaling   5
- Pharmacokinetics core concepts  

    - Bioavailability and first-pass metabolism   5
    - Compartment models and parameters   6
    - Organ failure effects on PK   5
    - Redistribution and tissue uptake   4
    - Special populations   5
- Toxicology and adverse drug reactions  

    - Dose-related vs idiosyncratic reactions   4
    - Local anesthetic systemic toxicity (principles)   5
    - Methemoglobinemia and CO toxicity (periop)   4
    - Opioid toxicity and reversal   4

####  Pharmacology, Microbiology &amp; Diagnostic Science (Core) 

   83   

  High-yield medication classes, antimicrobial principles, vaccination and infection concepts, plus di...

         - Diagnostic test interpretation and screening science  

    - Bias and confounding in diagnostic studies   3
    - Critical values and escalation thresholds   3
    - Reference ranges and pregnancy-adjusted labs   3
    - Screening program principles   3
    - Test characteristics and Bayes theorem intuition   3
- Gynecologic pharmacology and contraception hormones  

    - Antibiotics/antifungals commonly used in GYN   4
    - Combined hormonal contraception (CHC) pharmacology   3
    - Emergency contraception   2
    - Menopause therapies   3
    - Progestin-only methods   4
- Medication safety in pregnancy and lactation  

    - Medication safety in breastfeeding   3
    - Peripartum anesthesia/analgesia pharmacology basics   4
    - Pharmacovigilance and counseling resources   4
    - Principles of prescribing in pregnancy   3
    - Teratogenic medication classes (core list)   4
- Microbiology, immunology and infection prevention  

    - Immunization principles for OB-GYN   3
    - Postoperative and postpartum infections   5
    - Pregnancy infections   3
    - STI microbiology essentials   3
    - Vaginal microbiome and common vaginitis   4
- Obstetric medication classes  

    - Diabetes medications in pregnancy   3
    - Hypertension medications in pregnancy   3
    - Thromboprophylaxis and anticoagulants   3
    - Tocolytics and preterm birth meds   4
    - Uterotonics and postpartum hemorrhage meds   3

####  Physics, measurement, mathematics, statistics (foundations) 

   56   

         - Radiation, MRI, and ultrasound physics (foundations)  

    - Ionizing radiation basics   3
    - MRI environment hazards   4
    - Ultrasound fundamentals   4
- Electrical safety and basic electronics  

    - Electrical hazards in OR   5
    - Ohm’s law and power   5
- Flow, pressure, and resistance  

    - Laminar vs turbulent flow   5
    - Poiseuille and Bernoulli principles   5
- Gas laws and vapors relevant to anesthesia  

    - Core gas laws   5
    - Humidity and airway gas conditioning   5
    - Vaporization concepts   5
- Mathematics, dosing, and basic statistics  

    - Data interpretation basics   5
    - Unit conversions and drug calculations   5

####  Physiology &amp; Homeostasis 

   50   

  System physiology emphasizing integration and mechanisms behind common clinical syndromes.

         - Cardiovascular physiology  

    - ECG electrophysiology basics   4
    - Exercise physiology   3
    - Hemodynamics and cardiac output   3
    - Vascular biology   3
- Endocrine physiology  

    - Calcium and bone metabolism   4
    - Glucose homeostasis   4
    - Hypothalamic–pituitary axes   3
    - Thyroid hormone action   3
- Renal physiology &amp; volume regulation  

    - Acid–base renal handling   3
    - Glomerular filtration and hemodynamics   3
    - Tubular handling of electrolytes   3
    - Water balance   3
- Respiratory physiology  

    - Acid–base and respiratory compensation   3
    - Hypoxic pulmonary vasoconstriction   2
    - Lung mechanics   3
    - Ventilation/perfusion and gas exchange   3

####  Reproductive Endocrinology &amp; Menstrual Cycle Physiology 

   45   

  Hormonal regulation across lifespan: puberty, cycle, pregnancy, lactation, menopause; core board phy...

         - Hypothalamic–pituitary–ovarian (HPO) axis regulation  

    - Endometrial cycle and histology   3
    - FSH/LH actions and ovarian steroidogenesis   3
    - GnRH pulsatility and feedback loops   4
    - Ovulation physiology and luteal phase   3
    - Puberty physiology and normal variants   3
- Menopause and perimenopause physiology  

    - Cardiometabolic changes around menopause   3
    - Hormone therapy physiologic rationale and risks   4
    - Ovarian aging and follicular depletion   3
    - Premature ovarian insufficiency (POI) physiology   2
    - Urogenital atrophy (GSM) pathophysiology   3
- Pregnancy endocrine physiology  

    - Calcium/vitamin D and bone metabolism   3
    - hCG, corpus luteum rescue, and placental takeover   2
    - Insulin resistance and metabolic adaptations   3
    - Postpartum endocrine changes   3
    - Thyroid physiology in pregnancy   3

####  Respiratory physiology and acid–base 

   73   

         - Acid–base and electrolytes (physiology foundations)  

    - Anion gap and lactate interpretation   4
    - Henderson–Hasselbalch and bicarbonate buffering   5
    - Key electrolytes for anesthesia   5
    - Stewart/strong ion approach (conceptual)   5
- Control of breathing and perioperative respiratory depression  

    - Central and peripheral chemoreceptors   5
    - Neuromuscular weakness and ventilation   4
    - Ventilatory responses to anesthesia and opioids   4
- Gas exchange: diffusion, V/Q, shunt  

    - Alveolar gas equation and A–a gradient   5
    - CO2 transport and elimination   5
    - Hypoxic pulmonary vasoconstriction (HPV)   4
    - V/Q mismatch vs shunt vs diffusion limitation   5
- Lung volumes, compliance, resistance, and work of breathing  

    - Airway resistance and flow   4
    - Closing capacity and FRC   4
    - PFT patterns for anesthesia   5
    - Static and dynamic compliance   6
    - Ventilation distribution and time constants   3

###  Clinical Anaesthesia 

   135 questions   

####  Airway and ventilation fundamentals (clinical application) 

   21   

         - Basic mechanical ventilation during anesthesia  

    - Setting tidal volume, rate, FiO2, and PEEP   5
    - Ventilator alarms and immediate responses   4
- Mask ventilation and supraglottic airway use  

    - Positioning and airway maneuvers   4
    - SGA selection and placement   4
    - Troubleshooting ventilation   4

####  Common intraoperative problems and complications 

   41   

         - Hypotension and hypertension intraoperatively  

    - Differential diagnosis approach   4
    - Initial management principles   5
- Hypoxemia and ventilation problems  

    - Systematic approach (DOPES/DOPE)   6
    - Troubleshooting by monitors   5
- Perioperative hypothermia and shivering  

    - Recognition and prevention   5
    - Treatment of shivering   5
- Perioperative nausea and vomiting (PONV)  

    - Prophylaxis and treatment classes   5
    - Risk factors and risk scoring concepts   6

####  Conduct of general anesthesia (core workflow) 

   50   

         - Emergence and extubation  

    - Common emergence complications   5
    - Emergence planning   5
    - Extubation criteria and technique   5
- Induction of anesthesia  

    - Airway management during induction   5
    - Induction complications   3
    - IV induction technique selection   4
    - Preoxygenation   5
- Maintenance of anesthesia  

    - Balanced anesthesia and analgesia integration   5
    - Neuromuscular blockade management   5
    - TIVA principles   3
    - Volatile anesthesia principles   5

####  Fluids, electrolytes, and blood (intraoperative basics) 

   23   

         - Blood products and transfusion basics  

    - Blood conservation strategies (overview)   4
    - Components and expected effects   5
    - Transfusion reactions (recognize and act)   4
- Crystalloids and colloids  

    - Common fluids and compositions   5
    - Fluid therapy strategies (core concepts)   5

###  Critical Care And Pain 

   80 questions   

####  Core ICU physiology and organ support 

   52   

         - Nutrition and glycemic control (basics)  

    - Enteral vs parenteral nutrition concepts   4
    - Glycemic management principles   5
- Acid–base, electrolytes, and renal failure (ICU basics)  

    - AKI and renal replacement overview   4
    - Common ICU acid–base patterns   6
- Mechanical ventilation (ICU foundations)  

    - ARDS concept and lung-protective ventilation   3
    - Indications and basic settings   4
    - Weaning and extubation readiness (intro)   4
- Sedation, analgesia, and delirium (ICU foundations)  

    - Analgesia-first sedation concept   5
    - Delirium recognition and prevention   4
- Shock and sepsis fundamentals  

    - Basic infection management principles   4
    - Sepsis physiology concepts   5
    - Shock types and initial approach   4

####  Pain science and pain management foundations 

   28   

         - Chronic pain and palliative care concepts  

    - Cancer pain and terminal symptom control (intro)   5
    - Chronic pain syndrome overview   4
- Acute postoperative pain management  

    - Multimodal analgesia planning   5
    - Opioid stewardship basics   5
- Pain physiology  

    - Neuropathic pain mechanisms (intro)   4
    - Nociception pathways   5

###  Emergencies And Resuscitation 

   95 questions   

####  Airway emergencies and acute respiratory events 

   21   

         - Cannot intubate/cannot oxygenate (CICO) principles  

    - Front-of-neck access (principles)   5
    - Recognition and calling for help   5
- Laryngospasm, bronchospasm, and aspiration  

    - Aspiration management   3
    - Laryngospasm management   3
    - Severe bronchospasm management   5

####  Core resuscitation algorithms and perioperative arrest 

   23   

         - BLS/ACLS fundamentals for anesthesiologists  

    - ACLS medications (principles)   4
    - High-quality CPR and defibrillation   4
- Perioperative cardiac arrest: anesthesia-specific causes  

    - Airway and ventilation catastrophes   5
    - Drug-related and allergic causes   5
    - Hemorrhage and transfusion complications   5

####  Specific anesthesia crises (core board incidents) 

   37   

         - Anaphylaxis in the perioperative setting  

    - Immediate treatment   5
    - Post-crisis actions   4
    - Recognition and differential   5
- Local anesthetic systemic toxicity (LAST)  

    - Management   4
    - Recognition   5
- Malignant hyperthermia (MH)  

    - Immediate management   4
    - Post-event ICU management   5
    - Recognition   5

####  Trauma and shock (initial management for anesthesia trainees) 

   14   

         - Trauma assessment and hemorrhagic shock basics  

    - Damage control resuscitation principles   4
    - Primary survey concepts   6
    - Trauma airway considerations   4

###  Equipment And Monitoring 

   189 questions   

####  Anesthesia workstation, gas supply, and breathing systems 

   53   

         - Anesthesia machine components and safety systems  

    - Gas sources and pipeline/cylinder systems   6
    - Low-pressure system leaks and checks   3
    - O2 failure protection and alarms   4
    - O2 flush and backbar   5
    - Pressure regulators and flowmeters   5
- Breathing circuits and CO2 absorption  

    - Circle system function   4
    - CO2 absorbents and hazards   6
    - Mapleson circuits and indications   4
    - Pediatric circuit considerations   4
- Vaporizers and inhaled agent delivery  

    - Desflurane and specialized vaporizers   4
    - Low-flow anesthesia and gas analysis   3
    - Variable bypass vaporizer design   5

####  Infusion devices, suction, and temperature management 

   23   

         - Suction systems  

    - Suction types and troubleshooting   5
- Active warming and temperature monitoring devices  

    - Temperature measurement sites   5
    - Warming modalities   5
- Infusion pumps and syringe drivers  

    - High-alert medication safety   4
    - Pump mechanics and common errors   4

####  Safety, hazards, and OR environment 

   27   

         - Infection prevention and equipment reprocessing (OR basics)  

    - Reusable equipment cleaning   5
    - Standard precautions in anesthesia   5
- Medical gases, scavenging, and pollution  

    - Environmental exposure and staff safety   4
    - Scavenging systems   3
- Electrical, fire, and explosion safety  

    - Electrical injury prevention   5
    - OR fire triad and prevention   5

####  Standard and advanced monitoring (principles and troubleshooting) 

   54   

         - Blood pressure monitoring  

    - Invasive arterial BP   5
    - Noninvasive BP   4
- Capnography and gas analysis  

    - Capnogram interpretation   4
    - O2 and anesthetic agent analyzers   4
    - Sampling systems and failure modes   4
- ECG monitoring  

    - Lead systems and ischemia detection   4
    - Pacing and defibrillation interface   5
- Neuromuscular monitoring and depth of anesthesia  

    - Peripheral nerve stimulator patterns   5
    - Processed EEG concepts   5
    - Quantitative monitoring   4
- Pulse oximetry and plethysmography  

    - Pleth waveform clinical use   5
    - Principles and limitations   5

####  Ventilators, oxygenation, and airway equipment 

   32   

         - Airway devices and function checks  

    - Endotracheal tubes and cuffs   5
    - Facemask, oral/nasal airways, supraglottic airways   5
    - Laryngoscopy and adjuncts   6
- Anesthesia ventilators (modes and mechanics)  

    - Common modes used intraoperatively   5
    - PEEP and recruitment concepts   6
    - Ventilator failure and backup ventilation   5

###  Organ-Based Sciences 

   159 questions   

####  Cardiovascular disease pathophysiology for anesthesia 

   36   

         - Arrhythmias and conduction disease (periop significance)  

    - Atrial fibrillation/flutter   5
    - Bradyarrhythmias and blocks   4
- Ischemic heart disease and heart failure (foundations)  

    - Periop implications (intro)   5
    - Supply–demand mismatch and ischemia   5
    - Systolic vs diastolic failure basics   5
- Valvular disease physiology (core patterns)  

    - Aortic regurgitation   3
    - Aortic stenosis   5
    - Mitral stenosis/regurgitation   4

####  Hepatic, GI, hematologic, endocrine, and neuromuscular pathophysiology 

   62   

         - Endocrine and metabolic disease (periop physiology)  

    - Adrenal physiology   6
    - Diabetes physiology and stress response   5
    - Thyroid disease physiology   5
- GI physiology and aspiration risk  

    - Aspiration pneumonitis vs pneumonia   4
    - Gastric emptying and reflux physiology   5
- Hemostasis and transfusion physiology (foundations)  

    - Coagulation cascade and fibrinolysis   5
    - Physiology of anemia and transfusion triggers (intro)   4
    - Primary hemostasis   5
- Liver disease physiology for anesthesia  

    - Drug metabolism implications   5
    - Portal hypertension and ascites   5
    - Synthetic dysfunction and coagulopathy   5
- Neuromuscular disorders and NMJ pathophysiology  

    - Muscular dystrophy and rhabdomyolysis risk   4
    - Myasthenia gravis and Lambert–Eaton   4

####  Renal, electrolyte, and fluid pathophysiology 

   29   

         - Acute kidney injury (AKI) concepts  

    - Perioperative AKI risk factors   4
    - Pre-renal, intrinsic, post-renal mechanisms   5
- Fluid compartments and edema physiology  

    - Sodium and water disorders (overview)   5
    - Starling forces and interstitial edema   6
- Renal physiology relevant to anesthesia  

    - GFR and tubular handling basics   5
    - Renal blood flow and autoregulation   4

####  Respiratory disease pathophysiology for anesthesia 

   32   

         - Obstructive lung disease (asthma/COPD)  

    - Airflow obstruction mechanisms   5
    - Perioperative triggers and prevention   4
    - Ventilation strategies (principles)   4
- Obstructive sleep apnea and obesity hypoventilation  

    - Pathophysiology affecting anesthesia   5
    - Perioperative risk and monitoring principles   5
- Restrictive lung disease and pulmonary hypertension basics  

    - Pulmonary hypertension (intro)   4
    - Restrictive physiology (ILD)   5

###  Perioperative Medicine 

   121 questions   

####  Advanced perioperative evaluation and optimization 

   28   

         - Advanced cardiac risk assessment and testing (principles)  

    - Perioperative medication optimization   4
    - When to pursue further testing (conceptual)   5
- Perioperative anticoagulation and thrombosis management (advanced overview)  

    - Balancing bleeding vs thrombosis risk   6
    - Reversal and urgent surgery strategies   4
- Perioperative pulmonary optimization and risk reduction  

    - Postoperative pulmonary complication prevention   4
    - Smoking cessation and lung expansion strategies   5

####  Enhanced recovery and postoperative complications (consultant level) 

   23   

         - Enhanced Recovery After Surgery (ERAS) principles  

    - Core ERAS elements   5
    - Implementation and multidisciplinary coordination   5
- Major postoperative complications: prevention and early management  

    - AKI prevention and response   4
    - Delirium and cognitive disorders   5
    - Myocardial injury after noncardiac surgery (MINS) concept   4

####  Postoperative care and PACU management 

   29   

         - PACU handover and monitoring priorities  

    - PACU complications recognition   6
    - Structured handover content   6
- Postoperative analgesia planning (core)  

    - Multimodal analgesia   5
    - PCA principles   4
- Postoperative respiratory complications (core)  

    - Opioid-induced ventilatory impairment (OIVI)   4
    - Residual neuromuscular blockade   4

####  Preoperative assessment and optimization 

   41   

         - Perioperative medication management (foundations)  

    - Anticoagulants/antiplatelets (intro)   5
    - Cardiovascular meds   4
    - Diabetes medications   4
- Preanesthetic evaluation and risk stratification  

    - ASA physical status and limitations   4
    - Common risk tools (conceptual familiarity)   5
    - History and exam priorities   6
- Preoperative investigations and interpretation (core)  

    - ECG interpretation for preop clearance   5
    - Imaging and tests (when indicated)   4
    - Labs: CBC, electrolytes, renal, coagulation   4

###  Professionalism And Safety 

   79 questions   

####  Communication, teamwork, wellbeing, and equity 

   30   

         - Equity, bias, and professionalism  

    - Healthcare disparities relevant to anesthesia   6
    - Implicit bias and mitigation   6
- Clinician fatigue, impairment, and wellbeing  

    - Fatigue and performance   5
    - Substance use disorder and impairment (professional duties)   4
- Team communication in perioperative care  

    - Closed-loop communication and assertiveness   4
    - Managing conflict and speaking up   5

####  Ethics, consent, and medicolegal essentials 

   21   

         - Documentation, disclosure, and medico-legal risk  

    - Clinical documentation standards   3
    - Open disclosure after adverse events (concept)   4
- Do-not-resuscitate (DNR) and perioperative goals of care  

    - Required reconsideration concept   4
- Informed consent and decision-making capacity  

    - Capacity and surrogate decision-making   5
    - Elements of informed consent   5

####  Patient safety, human factors, and quality improvement 

   28   

         - Quality improvement (QI) basics  

    - Incident reporting and learning systems   4
    - QI methods and measurement   5
- Human factors and error science  

    - Systems approach to safety   5
    - Types of error and cognitive biases   6
- Medication safety in anesthesia  

    - Common anesthesia medication errors   4
    - Prevention strategies   4

###  Regional Anaesthesia 

   101 questions   

####  Local anesthetics and adjuvants (core pharmacology and safety) 

   27   

         - Local anesthetic pharmacology and dosing  

    - Ester vs amide LAs   5
    - Maximum dose principles   4
    - Mechanism and differential blockade   4
- Regional anesthesia complications: prevention and first response  

    - Infection and hematoma concepts   5
    - LAST recognition and management   4
    - Nerve injury mechanisms   5

####  Neuraxial anesthesia (spinal/epidural/CSE) 

   30   

         - Anticoagulation and neuraxial safety (principles)  

    - Risk assessment approach   5
- Epidural anesthesia/analgesia  

    - Complications and troubleshooting   5
    - Placement and dosing strategies   5
- Spinal anesthesia technique and physiology  

    - Drug choice and baricity   5
    - Post-dural puncture headache (PDPH)   5
    - Sympathectomy and hypotension   5

####  Peripheral and truncal blocks (principles and common blocks) 

   31   

         - Truncal blocks for perioperative analgesia  

    - Paravertebral and erector spinae plane blocks (intro)   4
    - TAP, rectus sheath, ilioinguinal/iliohypogastric   5
- Lower extremity blocks  

    - Fascia iliaca and hip analgesia concepts   5
    - Femoral/adductor canal and sciatic blocks   5
- Upper extremity blocks  

    - Brachial plexus approaches   5
    - Distal nerve blocks   7

####  Ultrasound and nerve localization fundamentals 

   13   

         - Ultrasound-guided regional anesthesia principles  

    - Nerve stimulation basics (as adjunct)   4
    - Probe handling and image optimization   5
    - Safety and injection technique   4

  Anesthesiology Advanced Pathway

###  Advanced Clinical Practice 

   49 questions   

####  Complex airway management and oxygenation strategies 

   22   

         - Advanced oxygenation and ventilation rescue  

    - Dynamic hyperinflation crisis   4
    - Severe hypoxemia management   4
- Difficult airway strategy selection and planning  

    - Awake intubation principles   4
    - Extubation of the difficult airway   5
    - RSI in high-risk patients   5

####  Hemodynamic optimization, transfusion, and advanced monitoring integration 

   27   

         - Advanced monitoring integration (exam-level)  

    - Cardiac output monitoring concepts   4
    - Central venous oxygen saturation and lactate   5
- Coagulation management and massive hemorrhage  

    - Massive transfusion protocols (MTP) and targets   5
    - Point-of-care coagulation testing (conceptual)   4
- Perioperative hypotension and shock: advanced approach  

    - Physiology-driven differential and therapy   5
    - Vasopressor/inotrope selection and titration   4

###  Advanced Sciences 

   59 questions   

####  Advanced pharmacology and physiology integration 

   23   

         - Advanced physiology under anesthesia (integrated)  

    - Cardiorespiratory interactions   5
    - Microcirculation and vasoplegia (concept)   5
- Advanced PK/PD in complex patients  

    - Drug–drug interactions in polypharmacy   4
    - Organ failure dosing strategies   4
    - Pharmacogenomics and atypical responses   5

####  Advanced physics, devices, and measurement 

   23   

         - Ultrasound and echocardiography fundamentals for advanced exams  

    - Basic perioperative echo concepts (not full TEE certification)   5
    - Point-of-care ultrasound principles   4
- Advanced monitoring signal interpretation  

    - Arterial waveform analysis (advanced basics)   5
    - Capnography as diagnostic tool   4
    - Processed EEG and EEG patterns (conceptual)   5

####  Evidence appraisal for guideline-based practice 

   13   

         - Clinical epidemiology and statistics for boards  

    - Diagnostic test performance   4
    - Effect sizes and interpretation   4
    - Study designs and bias   5

###  Crisis Management 

   43 questions   

####  Crisis resource management (CRM) and leadership 

   15   

         - CRM principles in anesthesia crises  

    - Debriefing and learning after events   5
    - Leadership, communication, and task allocation   5
    - Use of cognitive aids and checklists   5

####  High-stakes perioperative critical incidents (advanced oral-exam style) 

   28   

         - Airway catastrophes (advanced scenarios)  

    - CICO escalation and front-of-neck access   3
    - Peri-extubation airway obstruction   4
- Anaphylaxis, MH, LAST (advanced execution)  

    - Drug dosing under pressure and infusion setup   5
    - Post-crisis disposition and communication   5
- Massive hemorrhage and coagulopathy crisis leadership  

    - Coagulopathy-directed therapy (conceptual)   5
    - Early recognition and activation of MTP   6

###  Critical Care Medicine 

   56 questions   

####  Advanced shock, multi-organ failure, and renal replacement therapy 

   18   

         - CRRT and complex electrolyte management  

    - Choosing modality and dosing (conceptual)   5
    - Critical electrolyte disorders   5
- Vasopressor/inotrope strategies in shock  

    - Cardiogenic shock basics (periop interface)   5
    - Septic shock escalation   3

####  Advanced ventilatory support and respiratory failure 

   21   

         - ARDS and refractory hypoxemia management  

    - Adjunct therapies (conceptual)   4
    - ECMO basics (exam-level overview)   3
    - Ventilation strategy refinement   4
- Weaning, extubation, and tracheostomy considerations  

    - Post-extubation support strategies   5
    - Weaning failure causes   5

####  ICU infection, sedation, nutrition, and ethics (advanced) 

   17   

         - Antimicrobial stewardship and ICU infections  

    - Sepsis source control coordination   4
    - VAP/CLABSI/CAUTI prevention concepts   5
- ICU ethics and end-of-life care  

    - Goals-of-care discussions and capacity   5
    - Withdrawal of life-sustaining therapy (conceptual)   3

###  Non-Operating Room Care 

   30 questions   

####  Sedation/anesthesia outside the OR (environmental and clinical risk) 

   30   

         - ECT and procedural psychiatry anesthesia  

    - ECT physiology and anesthetic technique   5
- General NORA principles and patient selection  

    - Environment and emergency planning   4
    - Sedation continuum and monitoring standards   4
- GI endoscopy, interventional radiology, and cath lab sedation  

    - Cath lab/EP procedures anesthesia considerations   5
    - Endoscopy sedation risks   4
- MRI anesthesia and sedation  

    - Airway access limitations and planning   4
    - MRI hazards and compatibility   4

###  Organ System Management 

   69 questions   

####  Advanced cardiovascular and pulmonary disease management 

   18   

         - Pulmonary hypertension and RV failure  

    - Management principles   4
    - Triggers of RV decompensation   5
- Severe heart failure and cardiomyopathy perioperative management  

    - Intraop goals and rescue   4
    - Preop assessment and optimization concepts   5

####  Advanced endocrine, renal, hepatic, neuro, and heme management 

   51   

         - Advanced hepatic failure and encephalopathy  

    - Coagulopathy and bleeding/thrombosis balance   5
    - Hepatic encephalopathy and sedative sensitivity   5
- Advanced renal failure and dialysis interface  

    - ESRD perioperative considerations   4
    - RRT complications (conceptual)   6
- Complex coagulation disorders  

    - Anticoagulants and reversal strategies (advanced overview)   6
    - Inherited bleeding disorders (overview)   4
- Endocrine crises (board-relevant)  

    - DKA/HHS periop stabilization   4
    - Pheochromocytoma periop hemodynamics (conceptual)   3
    - Thyroid storm and myxedema coma (recognize/initial treat)   5
- Neurologic emergencies (periop)  

    - Acute stroke periop considerations (concept)   3
    - Increased ICP and herniation risk management   6

###  Pain Medicine 

   41 questions   

####  Acute pain, complex postoperative pain, and opioid stewardship 

   13   

         - Complex acute pain management (perioperative and ICU)  

    - Opioid-related harm reduction   4
    - Opioid-tolerant and opioid use disorder patients   4
    - Regional analgesia and catheter management   5

####  Chronic pain syndromes and interventional concepts (board-oriented) 

   18   

         - Interventional pain (conceptual awareness for anesthesia boards)  

    - Common procedures and indications (overview)   5
    - Complications and safety   4
- Neuropathic pain and common syndromes  

    - Central sensitization syndromes (overview)   5
    - Peripheral neuropathic pain   4

####  Palliative care and cancer pain 

   10   

         - Cancer pain management principles  

    - Opioids and adjuvants in cancer pain   5
    - Terminal symptom control   5

###  Perioperative Medicine 

   121 questions   

####  Advanced perioperative evaluation and optimization 

   28   

         - Advanced cardiac risk assessment and testing (principles)  

    - Perioperative medication optimization   4
    - When to pursue further testing (conceptual)   5
- Perioperative anticoagulation and thrombosis management (advanced overview)  

    - Balancing bleeding vs thrombosis risk   6
    - Reversal and urgent surgery strategies   4
- Perioperative pulmonary optimization and risk reduction  

    - Postoperative pulmonary complication prevention   4
    - Smoking cessation and lung expansion strategies   5

####  Enhanced recovery and postoperative complications (consultant level) 

   23   

         - Enhanced Recovery After Surgery (ERAS) principles  

    - Core ERAS elements   5
    - Implementation and multidisciplinary coordination   5
- Major postoperative complications: prevention and early management  

    - AKI prevention and response   4
    - Delirium and cognitive disorders   5
    - Myocardial injury after noncardiac surgery (MINS) concept   4

####  Postoperative care and PACU management 

   29   

         - PACU handover and monitoring priorities  

    - PACU complications recognition   6
    - Structured handover content   6
- Postoperative analgesia planning (core)  

    - Multimodal analgesia   5
    - PCA principles   4
- Postoperative respiratory complications (core)  

    - Opioid-induced ventilatory impairment (OIVI)   4
    - Residual neuromuscular blockade   4

####  Preoperative assessment and optimization 

   41   

         - Perioperative medication management (foundations)  

    - Anticoagulants/antiplatelets (intro)   5
    - Cardiovascular meds   4
    - Diabetes medications   4
- Preanesthetic evaluation and risk stratification  

    - ASA physical status and limitations   4
    - Common risk tools (conceptual familiarity)   5
    - History and exam priorities   6
- Preoperative investigations and interpretation (core)  

    - ECG interpretation for preop clearance   5
    - Imaging and tests (when indicated)   4
    - Labs: CBC, electrolytes, renal, coagulation   4

###  Quality And Professional Practice 

   43 questions   

####  Ethics, professionalism, equity, and practice management (advanced) 

   22   

         - Equity-focused professional practice  

    - Reducing disparities in perioperative outcomes   4
- Practice management and medico-legal readiness (overview)  

    - Credentialing and maintenance of competence (concept)   5
    - Documentation quality and billing integrity (conceptual)   5
- Complex ethical scenarios in perioperative care  

    - Refusal of blood products and capacity   4
    - Resource allocation and triage (concept)   4

####  Governance, regulation, and systems-based practice 

   21   

         - Clinical governance and quality systems  

    - Incident investigation and risk management   5
    - Quality measurement and improvement at department level   5
- Scope of practice, supervision, and education  

    - Supervision and delegation in anesthesia care teams   5
    - Teaching and assessment responsibilities   6

###  Subspecialty Anaesthesia 

   83 questions   

####  High-yield subspecialty surgery anesthesia 

   83   

         - Cardiac and major vascular anesthesia (exam-level overview)  

    - Aortic surgery and cross-clamping physiology   5
    - CABG/valve surgery physiology concepts   5
    - Endovascular procedures (EVAR/TEVAR) considerations   5
- ENT/shared airway and ophthalmic anesthesia  

    - Ophthalmic-specific reflexes and considerations   4
    - Shared airway management   5
- Neurosurgical anesthesia  

    - Craniotomy physiology and goals   4
    - Spine surgery considerations   5
- Obstetric anesthesia  

    - Labor analgesia and neuraxial anesthesia   6
    - Obstetric emergencies (exam core)   5
    - Physiologic changes of pregnancy relevant to anesthesia   4
- Orthopedic, trauma, burns, and ambulatory anesthesia  

    - Ambulatory anesthesia patient selection and discharge   6
    - Burns anesthesia considerations   3
    - Major joint arthroplasty considerations   4
    - Trauma anesthesia (advanced emphasis)   4
- Pediatric anesthesia  

    - Pediatric airway and physiology differences   5
    - Pediatric induction and emergence   4
- Thoracic anesthesia and one-lung ventilation  

    - Hypoxemia during OLV   4
    - Lung isolation devices and confirmation   5

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