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3. Emergency Medicine

  Emergency Medicine curriculum 
===============================

 Conquer Emergency Medicine Boards with Confidence

      Core   Advanced   

    Emergency Medicine Core Pathway

###  Basic Sciences 

   2,168 questions   

####  Anatomy for anesthesia (airway, neuraxial, vascular, regional) 

   50   

         - Neuraxial anatomy and dermatomes  

    - Dermatome and block height assessment   4
    - Meninges and CSF spaces   4
    - Vertebral column and ligamentous structures   4
- Peripheral nerve anatomy (regional anesthesia essentials)  

    - Brachial plexus overview   5
    - Lower limb plexuses   5
    - Truncal blocks anatomy   5
- Upper airway anatomy and airway assessment landmarks  

    - Airway examination correlates   5
    - Nasal and oral cavity anatomy   4
    - Pharynx and larynx anatomy   5
- Vascular access anatomy  

    - Arterial access anatomy   4
    - Central venous anatomy   5

####  Anatomy, Surgical Anatomy &amp; Pelvic Support 

   70   

  Gross and applied anatomy relevant to obstetrics, gynecology, pelvic surgery, continence/prolapse, a...

         - Adnexa and tubo-ovarian anatomy  

    - Broad ligament spaces and adnexal torsion anatomy   2
    - Fallopian tube segments and function   3
    - Ovary—blood supply and surgical implications   2
    - Parametrium and ureteric course   2
    - Pelvic sidewall landmarks   3
- Bony pelvis, pelvic diameters, and obstetric biomechanics  

    - Anatomy relevant to operative vaginal birth   3
    - Maternal pelvis shapes and relevance   3
    - Mechanisms of labor and fetal head molding   3
    - Pelvic floor interaction with birth   3
    - Pelvimetry concepts and clinical utility   2
- Breast anatomy and lactation-relevant structures  

    - Breast ducts, lobules, and lymphatics   3
    - Breast imaging anatomy correlation   2
    - Nipple–areolar complex anatomy   3
    - Physiology-anatomy interface in lactation   3
    - Surgical anatomy (duct excision, abscess drainage) basics   3
- Pelvic floor, continence mechanisms and anorectal anatomy  

    - Anal sphincter complex   4
    - Levator ani and fascial supports   3
    - Lower urinary tract anatomy   2
    - Neurovascular anatomy relevant to pelvic pain   3
    - Perineum and episiotomy landmarks   3
- Uterus, cervix, vagina and vulva—applied anatomy  

    - Cervical anatomy and transformation zone   2
    - Lymphatic drainage of lower genital tract   3
    - Uterine layers and supporting ligaments   3
    - Vaginal anatomy and fornices   3
    - Vulvar anatomy   4

####  Applied Anatomy for Emergency Care 

   117   

  Regional anatomy relevant to resuscitation, procedures, and time-critical diagnosis.

         - Abdominal and pelvic anatomy for acute abdomen  

    - Appendix, bowel, mesentery   5
    - Genitourinary anatomy   5
    - Hepatobiliary and pancreatic anatomy   5
    - Pelvic anatomy and hemorrhage   3
    - Peritoneal spaces and referred pain   5
- Airway, neck, and upper aerodigestive anatomy  

    - Airway edema/obstruction implications   5
    - Larynx and trachea   4
    - Neck vascular/nerve structures   4
    - Surgical airway anatomy (foundational)   4
    - Upper airway landmarks   5
- Musculoskeletal compartments and vascular anatomy  

    - Compartment syndrome anatomy   4
    - Fracture patterns and growth plates (intro)   5
    - Major joints: stability and reduction basics   5
    - Ultrasound-relevant vascular anatomy   5
    - Vascular anatomy for hemorrhage control   5
- Neuroanatomy and spinal anatomy for EM  

    - Cerebral vascular territories (exam-relevant)   5
    - Intracranial compartments and herniation   4
    - Ocular and orbital anatomy   5
    - Peripheral nerve anatomy for injuries/blocks   5
    - Spinal cord/nerve root anatomy   5
- Thoracic anatomy and pleura  

    - Chest wall, ribs, diaphragm   5
    - Mediastinum and great vessels   6
    - Pericardium and cardiac anatomy basics   5
    - Pleural spaces and lung lobes   5
    - Procedural anatomy (thoracic)   3

####  Biochemistry, Metabolism &amp; Nutrition 

   37   

  Core metabolic pathways, organ metabolism, and clinically important deficiencies/excesses.

         - Carbohydrate and lipid metabolism (clinically applied)  

    - Glycolysis/gluconeogenesis concepts   3
    - Inborn errors (overview)   4
    - Lipid metabolism   3
    - Obesity and insulin resistance   2
- Micronutrients and deficiency syndromes  

    - Fat-soluble vitamins   3
    - Refeeding syndrome   3
    - Trace elements   3
    - Water-soluble vitamins   3
- Protein metabolism and liver synthetic function  

    - Albumin and oncotic pressure   4
    - Amino acid metabolism   4
    - Bilirubin metabolism   3
    - Coagulation factors synthesis   2

####  Cardiovascular physiology and measurement 

   71   

         - Cardiac electrophysiology and ECG basics  

    - Arrhythmia mechanisms (exam core)   5
    - Cardiac action potentials   4
    - Conduction system anatomy/physiology   5
    - Defibrillation/cardioversion principles   5
    - ECG interpretation for anesthesia   5
- Cardiac pump function and determinants of CO  

    - Autonomic control of circulation   5
    - Determinants of SVR and MAP   4
    - Frank–Starling physiology   5
    - Myocardial oxygen supply/demand   5
    - Pressure–volume concepts   6
    - Shock physiology (core principles)   5
- Oxygen transport and hemodynamic oxygenation metrics  

    - Hemoglobin–oxygen dissociation curve   4
    - Microcirculation basics   5
    - Oxygen consumption and extraction   4
    - Oxygen content and delivery   4

####  Cellular &amp; Molecular Biology 

   43   

  Core cellular structure/function and signaling relevant to disease mechanisms and therapeutics.

         - Cell structure, organelles, and trafficking  

    - Cell cycle, apoptosis, necrosis   3
    - Cell–cell junctions and extracellular matrix   4
    - Membrane structure &amp; transport   4
    - Organelles and key functions   4
- Oncogenesis fundamentals  

    - Cancer immunology (intro)   3
    - Carcinogenesis &amp; exposures   3
    - Hallmarks of cancer (board-level)   3
    - Tumor suppressors and oncogenes   4
- Signal transduction &amp; second messengers  

    - Inflammation signaling   4
    - Pharmacologic implications   3
    - Receptor classes   4
    - Second messengers   4

####  Clinical epidemiology, biostatistics, and evidence-based practice 

   55   

  Board-relevant study design, diagnostic testing performance, screening, clinical decision-making, an...

         - Basic statistics interpretation (board level)  

    - Confidence intervals   3
    - Hypothesis testing and p-values   3
    - Inter-rater reliability and kappa   2
    - Measures of central tendency and spread   3
    - Regression basics (conceptual)   3
- Diagnostic test characteristics  

    - Decision rules (e.g., PECARN concept)   3
    - Interpreting lab reference ranges in pediatrics   3
    - Likelihood ratios and post-test probability   2
    - ROC curves and thresholds (conceptual)   2
    - Sensitivity, specificity, predictive values   3
- Screening principles and prevention evidence  

    - Clinical practice guidelines (CPGs)   3
    - Criteria for screening programs   4
    - Ethics in evidence application   3
    - Number needed to treat/harm   3
    - Public health measures and outbreak basics   2
- Study designs and hierarchy of evidence  

    - Diagnostic test studies   3
    - Interventional studies (RCTs)   3
    - Observational studies (cohort, case-control, cross-sectional)   2
    - Quality improvement vs research (distinction)   3
    - Systematic reviews and meta-analyses   2

####  Clinical pharmacology and therapeutics (core) 

   76   

  Weight-based dosing, pediatric pharmacokinetics/dynamics, antimicrobial fundamentals, common drug cl...

         - Analgesia, sedation, and peri-procedural medications  

    - Common agents and adverse effects   4
    - Local anesthetics and toxicity   4
    - Non-opioid analgesics   3
    - Opioids and respiratory depression risk   3
    - Procedural sedation core concepts   4
- Antimicrobial classes and selection (foundational)  

    - Aminoglycosides and nephro/ototoxicity   2
    - Antiviral/antifungal overview (core)   3
    - Beta-lactams and cephalosporins   4
    - Macrolides and atypical coverage   3
    - MRSA agents (clindamycin, TMP-SMX, vancomycin, linezolid)   2
- Common pediatric chronic medication classes (core board level)  

    - Antiepileptic drugs overview   3
    - Asthma/allergy pharmacotherapy basics   4
    - Cardiac medications basics   3
    - Endocrine medications basics   3
    - Psychotropic basics (overview)   3
- Pediatric dosing principles and medication safety  

    - Adverse drug reaction types   3
    - Medication reconciliation and error prevention   3
    - Routes of administration and bioavailability   3
    - Therapeutic drug monitoring (TDM) basics   3
    - Weight-based dosing and dose limits   2
- Pediatric pharmacokinetics and pharmacodynamics  

    - Absorption differences by age   3
    - Distribution (body water/fat, protein binding)   3
    - Elimination (renal maturation)   3
    - Metabolism (hepatic enzymes)   2
    - Pharmacogenomics basics (board overview)   3

####  Core anesthesia pharmacology (drug classes) 

   95   

         - Cardiovascular drugs commonly used in anesthesia  

    - Antiarrhythmics (core familiarity)   4
    - Antihypertensives and antianginals   5
    - Vasopressors and inotropes   6
- Inhalational anesthetics  

    - MAC and factors affecting MAC   6
    - Organ effects and toxicity   6
    - Special phenomena   5
    - Uptake and distribution   4
- Intravenous induction agents and sedatives  

    - Benzodiazepines   4
    - Dexmedetomidine and alpha-2 agonists   4
    - Etomidate   4
    - Ketamine   5
    - Propofol   5
- Neuromuscular blockers and reversal agents  

    - Depolarizing blockade (succinylcholine)   4
    - Monitoring and reversal   4
    - NMJ physiology relevant to blockade   5
    - Nondepolarizing blockade   4
- Opioids and adjunct analgesics  

    - Adjuvant analgesics (exam-relevant)   4
    - Common IV opioids in anesthesia   5
    - Non-opioid analgesics (core)   5
    - Opioid receptor pharmacology   6

####  Core Physiology and Pathophysiology 

   147   

  High-yield physiologic principles that underpin ED presentation patterns and first-line therapy.

         - Acid–base physiology and interpretation  

    - Metabolic acidosis   4
    - Metabolic alkalosis   5
    - Osmolar gap and toxin clues   4
    - Respiratory acidosis/alkalosis   5
    - Systematic interpretation approach   5
- Inflammation, immunity, and sepsis pathobiology  

    - Anaphylaxis physiology   5
    - Coagulation-inflammation interface   5
    - Fever physiology   4
    - Host response to infection   6
    - Vaccines, immunization status, and ED relevance   5
- Neurophysiology of consciousness, seizure, and delirium  

    - Delirium and encephalopathy mechanisms   3
    - Raised ICP physiology   4
    - Reticular activating system and coma basics   6
    - Seizure generation and termination (conceptual)   4
    - Temperature and CNS function   5
- Oxygen delivery, shock physiology, and perfusion  

    - Determinants of oxygen delivery   4
    - Fluid responsiveness and endpoints   5
    - Reperfusion and resuscitation complications   5
    - Shock classification and physiology   6
    - Vasopressors/inotropes physiology   6
- Renal physiology and electrolyte homeostasis  

    - Acute kidney injury pathophysiology   6
    - Calcium, magnesium, phosphate physiology   6
    - Diuretics and renal pharmacodynamics (intro)   5
    - Potassium physiology and membrane excitability   6
    - Sodium and water balance   5
- Respiratory mechanics and gas exchange  

    - Acid-base interplay in respiratory disease   4
    - Hypoxemia mechanisms   5
    - Ventilation strategy principles (intro)   5
    - Ventilation vs oxygenation concepts   5
    - Work of breathing and fatigue   4

####  Developmental physiology and anatomy 

   103   

  Age-dependent structure and function across fetal, neonatal, infant, child, and adolescent stages re...

         - GI, hepatic, and pancreatic developmental physiology  

    - Bilirubin metabolism   2
    - Feeding physiology and gastric emptying   4
    - Gut microbiome concepts (board-relevant)   3
    - Liver synthetic function and vitamin K   3
    - Pancreatic function maturation   2
- Neurodevelopmental physiology (foundation)  

    - Brain development timing and vulnerability   3
    - Intracranial pressure basics   3
    - Pain pathways and developmental differences   3
    - Seizure physiology overview   3
    - Sleep physiology across development   3
- Fetal-to-neonatal transition physiology  

    - Cardiovascular transition and shunts   3
    - Neonatal glucose homeostasis   3
    - Placental to pulmonary gas exchange transition   3
    - Respiratory adaptation   3
    - Thermoregulation at birth   3
- Hematopoiesis and pediatric hemostasis basics  

    - Age-based CBC norms   3
    - Coagulation and bleeding evaluation foundations   3
    - Hemoglobin switching and oxygen affinity   3
    - Iron metabolism and erythropoiesis   3
    - Transfusion medicine basics   4
- Pediatric cardiovascular physiology basics  

    - Blood pressure norms and perfusion   3
    - Cardiac output determinants by age   2
    - Congenital heart physiology patterns   3
    - Oxygen delivery and consumption   2
    - Shock physiology overview   3
- Pediatric respiratory mechanics basics  

    - Age-dependent airway anatomy   3
    - Basic blood gas interpretation   4
    - Pulmonary defense mechanisms   3
    - Ventilation-perfusion relationships   3
    - Work of breathing and fatigue   2
- Renal maturation and fluid homeostasis  

    - Acid handling and bicarbonate physiology   3
    - Neonatal electrolyte vulnerabilities   3
    - Neonatal renal function and GFR maturation   3
    - Urine output norms and interpretation   3
    - Water balance regulation   3

####  Embryology, Fetal Development &amp; Congenital Anomalies 

   42   

  Embryology and developmental physiology underpinning congenital anomalies and reproductive tract dis...

         - Gametogenesis, fertilization, implantation and early placentation  

    - Amniotic fluid development and regulation   3
    - Fertilization and early embryo development   2
    - Implantation physiology and abnormal implantation   3
    - Oogenesis and spermatogenesis essentials   3
    - Placental development and cord formation   3
- Müllerian development and reproductive tract anomalies  

    - Cervical insufficiency developmental considerations   2
    - Congenital anomalies—screening principles   3
    - Müllerian duct fusion and canalization   3
    - Ovarian and testicular differentiation   3
    - Urogenital sinus development   2
- Organogenesis and teratology timing  

    - Common teratogens and patterns   5
    - Congenital infection pathogenesis (TORCH concept)   3
    - Critical periods of development   2
    - Fetal growth regulation   2
    - Placental transfer and fetal drug exposure   3

####  Emergency Pharmacology and Therapeutics 

   117   

  PK/PD and emergency drug classes frequently tested and used in ED resuscitation and symptom control.

         - Analgesia in emergency medicine  

    - Ketamine for analgesia   3
    - Non-opioid analgesics   5
    - Opioid pharmacology and safe prescribing   6
    - Pain syndromes and multimodal strategy   4
    - Regional anesthesia principles (intro)   5
- Antimicrobials and stewardship essentials  

    - Allergy, anaphylaxis, and cross-reactivity   5
    - Antibiotic adverse effects   5
    - Antiviral/antifungal (board-level)   5
    - Empiric antibiotic selection principles   4
    - High-yield ED syndromes (empiric)   4
- Cardiovascular and vasoactive medications  

    - Antiarrhythmics and rate control   5
    - Antihypertensives in emergencies   5
    - Antithrombotics and reperfusion adjuncts   6
    - Reversal agents (core overview)   5
    - Vasopressors/inotropes   5
- Pharmacokinetics/pharmacodynamics in the ED  

    - Absorption, distribution, metabolism, elimination   4
    - Drug interactions and adverse drug events   5
    - Medication safety principles   5
    - Onset/offset and context-sensitive half-time   5
    - Pharmacogenomics and variability (board-level)   3
- Sedation, induction agents, and anxiolysis  

    - Benzodiazepines   5
    - Dexmedetomidine (board-level overview)   4
    - Ketamine dissociation   4
    - Procedural sedation safety   5
    - Propofol and etomidate basics   5

####  Epidemiology, Biostatistics &amp; Evidence-Based Medicine 

   45   

  Study design, bias, test performance, causality, and applying evidence to patient care.

         - Clinical guidelines and evidence synthesis  

    - Ethics in research   3
    - GRADE and strength of recommendation   3
    - Implementation and de-implementation   3
    - Systematic reviews/meta-analyses   3
- Diagnostic test interpretation  

    - Bayesian reasoning   2
    - Core measures   3
    - ROC curves and thresholds   2
    - Screening principles   3
- Study design and validity  

    - Bias and confounding   3
    - Causality and inference   3
    - Interventional trials   3
    - Observational designs   4
- Treatment effects and risk  

    - Decision analysis basics   3
    - Effect size measures   2
    - Heterogeneity and subgroup analyses   3
    - Time-to-event analysis   2

####  Fluids, electrolytes, and acid–base 

   83   

  Core calculations and physiologic reasoning for pediatric fluid management, electrolyte abnormalitie...

         - Calcium, magnesium, and phosphate disorders  

    - Hypercalcemia differential and initial workup   2
    - Hypomagnesemia and refractory hypokalemia/hypocalcemia   2
    - Neonatal hypocalcemia (early/late)   3
    - Phosphate abnormalities (refeeding, DKA)   3
    - QT prolongation and electrolyte-related arrhythmias   3
- Acid–base disorders and interpretation  

    - Bicarbonate therapy: indications and risks   4
    - Metabolic acidosis differential (high vs normal anion gap)   4
    - Metabolic alkalosis differential   3
    - Respiratory acidosis/alkalosis scenarios   3
    - Stepwise blood gas interpretation   3
- Hypernatremia in children  

    - Central diabetes insipidus management   3
    - Correction strategy and monitoring   3
    - Etiologies and diagnostic approach   3
    - Nephrogenic diabetes insipidus basics   2
    - Neurologic complications of dysnatremias   2
- Hyponatremia in children  

    - Acute symptomatic hyponatremia management   3
    - Classification by volume status   3
    - Osmotic demyelination risk   2
    - Pseudohyponatremia and lab pitfalls   3
    - SIADH approach   3
- Maintenance fluids and dehydration management  

    - Assessment of dehydration severity   3
    - Hypernatremic dehydration   2
    - IV fluid bolus and deficit replacement   3
    - Maintenance fluid calculation and composition   3
    - Oral rehydration therapy (ORT)   2
- Potassium disorders (hypo/hyperkalemia)  

    - Hyperkalemia emergency management   3
    - Hyperkalemia recognition and ECG changes   3
    - Hypokalemia causes and evaluation   2
    - Renal tubular disorders related to potassium   3
    - Replacement strategies and safety   2

####  Genetics &amp; Genomics 

   31   

  Mendelian and complex genetics, genomic medicine, and clinically actionable variants.

         - Complex traits and gene–environment interaction  

    - Epigenetics   3
    - Microbiome (board-level concepts)   2
    - Polygenic risk concepts   3
    - Somatic mosaicism &amp; clonal hematopoiesis   2
- Genomic testing in clinical practice  

    - Ethical issues   2
    - Pharmacogenomics   3
    - Testing modalities   2
    - Variant interpretation   3
- Mendelian inheritance and risk  

    - Autosomal dominant patterns   3
    - Autosomal recessive patterns   3
    - Mitochondrial inheritance   2
    - X-linked inheritance   3

####  Genetics and metabolism (introductory) 

   57   

  Foundations of inheritance, genetic testing, dysmorphology approach, and introductory inborn error r...

         - Dysmorphology and congenital anomaly approach  

    - Approach to a dysmorphic child   3
    - Common genetic syndromes (core list)   3
    - Referral and multidisciplinary care   2
    - Syndromic vs sequence vs association concepts   3
    - Teratology basics   4
- Inborn errors: pattern recognition (intro)  

    - Hypoglycemia patterns and ketones   3
    - Lactic acidosis and mitochondrial disease overview   2
    - Metabolic acidosis and hyperammonemia patterns   3
    - Newborn with lethargy/vomiting after feeds   3
    - Recurrent rhabdomyolysis and exercise intolerance   2
- Genetic testing modalities and indications  

    - Ethical considerations in pediatric genetics   2
    - Karyotype, microarray, and targeted panels   3
    - Newborn screening follow-up basics   3
    - Prenatal testing concepts (board-level)   2
    - Single-gene sequencing and exome/genome sequencing   3
- Patterns of inheritance and pedigree interpretation  

    - Autosomal dominant/recessive patterns   3
    - Chromosomal abnormalities overview   4
    - De novo variants and recurrence risk   3
    - Multifactorial inheritance and risk   3
    - X-linked and mitochondrial inheritance   3

####  Genetics, Immunology, Hematology &amp; Teratology 

   65   

  Genetic principles, prenatal screening/diagnosis frameworks, immunohematology (Rh), and teratology r...

         - Genetic inheritance and counseling fundamentals  

    - Carrier screening concepts   4
    - Chromosomal abnormalities and mechanisms   4
    - Consanguinity and risk quantification basics   2
    - Genetic test ethics and informed consent   3
    - Patterns of inheritance   4
- Immunohematology and alloimmunization  

    - Fetal anemia assessment principles   2
    - Non-D antibodies and clinical relevance   3
    - RhD immunization prevention   3
    - Thrombophilia concepts   3
    - Transfusion medicine basics in OB   4
- Prenatal screening and diagnostic testing  

    - Aneuploidy screening modalities   3
    - Diagnostic procedures principles   3
    - Neural tube defect screening and diagnosis   4
    - Non-immune hydrops framework   3
    - Screening test performance interpretation   3
- Teratology and environmental exposures  

    - Infections as teratogens (TORCH)   4
    - Medication risk frameworks   3
    - Occupational/environmental hazards   4
    - Radiation exposure in pregnancy   3
    - Substance use and fetal effects   3

####  Hematology, Transfusion, and Evidence-Based Medicine 

   94   

  Coagulation, transfusion science, and biostatistics/EBM essentials commonly assessed in EM training...

         - EBM in practice: guidelines, pathways, and stewardship  

    - Antimicrobial and imaging stewardship   4
    - Applying guidelines safely   3
    - Critical incident literature appraisal (M&amp;M style)   4
    - Quality metrics vs patient-centered outcomes   4
    - Screening and prevention in ED context   5
- Biostatistics and clinical epidemiology for EM  

    - Bias, confounding, and validity   4
    - Clinical prediction rules and implementation   6
    - Diagnostic test performance   5
    - Measures of effect and uncertainty   4
    - Study designs and hierarchy of evidence   5
- Hemostasis and coagulation fundamentals  

    - Bleeding risk stratification (conceptual)   4
    - Coagulopathies in the ED   6
    - Heparin/DOAC physiology and lab interpretation   5
    - Primary vs secondary hemostasis   6
    - Thrombosis physiology   5
- Transfusion medicine and massive hemorrhage basics  

    - Blood products and indications   5
    - Hemolysis and anemia emergencies   5
    - Massive transfusion principles   5
    - Rh/alloimmunization principles (ED-relevant)   4
    - Transfusion reactions   5

####  Immunology &amp; Inflammation 

   36   

  Innate/adaptive immunity, hypersensitivity, autoimmunity, immunodeficiency, and transplant fundament...

         - Adaptive immunity  

    - B cell biology and antibodies   4
    - Hypersensitivity reactions   3
    - T cell biology   3
    - Vaccinology principles   2
- Autoimmunity and tolerance  

    - Central and peripheral tolerance   3
    - Immunodeficiency overview   3
    - Systemic autoimmune disease mechanisms   3
    - Transplant immunology (intro)   3
- Innate immunity and inflammation  

    - Complement system   3
    - Inflammation resolution   3
    - Pattern recognition and cytokines   3
    - Phagocytes and granulomatous inflammation   3

####  Immunology, inflammation, and allergy foundations 

   84   

  Fundamental immune mechanisms, hypersensitivity, primary immunodeficiency red flags, and vaccine imm...

         - Autoimmunity and immune dysregulation fundamentals  

    - Autoantibodies and immune tolerance concepts   3
    - Autoinflammatory syndromes (intro)   4
    - Cytokine storm/HLH conceptual bridge   3
    - Cytopenias and autoimmune disease links   3
    - Immune-mediated kidney and skin disease examples   3
- Hypersensitivity and allergic disease mechanisms  

    - Atopic disease spectrum   4
    - Drug allergy vs intolerance   3
    - Food allergy mechanisms and tolerance   4
    - Type I (IgE-mediated) reactions   4
    - Type II/III/IV hypersensitivity examples   4
- Innate and adaptive immune system basics  

    - Adaptive immunity components   4
    - Complement system basics   3
    - Inflammation resolution and chronic inflammation   3
    - Innate immunity components   4
    - Mucosal immunity and IgA   3
- Primary immunodeficiency (PID) overview and red flags  

    - Basic lab evaluation of immune function   3
    - Clinical warning signs and patterns   3
    - Immunization considerations in immunocompromise   3
    - Secondary immunodeficiency causes   3
    - T-cell vs B-cell vs phagocyte vs complement defects   4
- Vaccine immunology foundations  

    - Active vs passive immunity principles   3
    - Adjuvants and immunogenicity   3
    - Herd immunity and population impact (exam framing)   4
    - Live attenuated vs inactivated vaccines   3
    - Vaccine adverse events and safety systems   3

####  Maternal–Fetal Physiology, Placenta &amp; Parturition 

   55   

  Pregnancy adaptations, uteroplacental unit physiology, and labor physiology essential for safe obste...

         - Maternal cardiovascular and hemodynamic adaptations  

    - Blood pressure physiology across trimesters   3
    - Changes in blood volume, CO, SVR   3
    - Coagulation physiology (hypercoagulability)   2
    - Postpartum hemodynamic shifts   3
    - Uterine blood flow physiology   2
- Placental function, transport, and endocrine activity  

    - Amniotic fluid dynamics   3
    - Maternal–fetal immunology   2
    - Placental endocrine hormones   3
    - Placental transport mechanisms   3
    - Umbilical and fetal circulation physiology   3
- Respiratory, renal, and acid–base physiology in pregnancy  

    - GI/hepatic adaptations   3
    - Hematologic adaptations beyond coagulation   3
    - Renal changes and lab interpretation   3
    - Thermoregulation and skin changes   3
    - Ventilatory changes and ABG interpretation   2
- Uterine contractility and cervical remodeling  

    - Cervical ripening mechanisms   3
    - Lactation physiology   3
    - Myometrial excitation–contraction coupling   2
    - Postpartum uterine involution   2
    - Stages of labor physiology   4

####  Neurophysiology, autonomics, and thermoregulation 

   43   

         - Autonomic nervous system and reflexes  

    - Autonomic failure and dysautonomia   6
    - Key perioperative reflexes   5
    - Sympathetic vs parasympathetic physiology   5
- Cerebral blood flow and intracranial dynamics  

    - CBF regulation   5
    - CSF production and drainage   4
    - ICP physiology   4
- Thermoregulation and perioperative hypothermia  

    - Anesthesia effects on temperature   5
    - Complications of hypothermia   4
    - Normal thermoregulatory control   5

####  Nutrition, growth biology, and metabolic fundamentals 

   76   

  Core pediatric nutrition and metabolism including breastfeeding, micronutrients, malnutrition, obesi...

         - Energy metabolism and common IEM overview (intro)  

    - Acute metabolic decompensation first steps   2
    - Basic pathways (glycogen, FAO, urea cycle)   4
    - Hypoglycemia differential by age   3
    - Newborn screen concept and limitations   2
    - When to refer for metabolic/genetic evaluation   3
- Failure to thrive (FTT) and malnutrition  

    - Definitions and anthropometric assessment   3
    - Differential diagnosis framework   3
    - Initial evaluation and targeted testing   3
    - Multidisciplinary management and safeguarding interface   3
    - Nutritional rehabilitation   3
- Infant feeding (breastfeeding and formula)  

    - Breast milk composition and benefits (exam framing)   2
    - Complementary feeding and allergen introduction   4
    - Feeding difficulties and red flags   3
    - Formula types and indications   4
    - Lactation management basics   3
- Micronutrients and deficiency states  

    - Iodine and thyroid development   3
    - Iron deficiency and anemia prevention   2
    - Vitamin A, E, K deficiencies (board-relevant)   4
    - Vitamin D and calcium   4
    - Zinc and trace elements   3
- Pediatric obesity and metabolic risk  

    - BMI classification and staging   4
    - Lifestyle intervention fundamentals   2
    - Metabolic syndrome and NAFLD overview   3
    - Obesity pharmacotherapy and bariatric basics (board overview)   3
    - Weight stigma and counseling skills   3

####  Pathology &amp; General Pathophysiology 

   35   

  General injury, repair, vascular pathology, thrombosis, and systemic responses to illness.

         - Cell injury and adaptation  

    - Amyloidosis (overview)   3
    - Edema and effusions pathophysiology   3
    - Inflammation and repair   3
    - Reversible vs irreversible injury   3
- Fever, SIRS, and sepsis biology  

    - Biomarkers (concepts)   3
    - Cytokine-mediated shock   3
    - Organ dysfunction mechanisms   3
    - Stress response and endocrine changes   3
- Hemostasis and thrombosis (mechanisms)  

    - Atherosclerosis &amp; aneurysm pathophysiology   3
    - Coagulation cascade (clinical interpretation)   3
    - Platelet biology   2
    - Thrombosis and embolism   3

####  Pathology, Neoplasia, and Breast Pathology Foundations 

   73   

  Core gynecologic and obstetric pathology and tumor biology underpinning screening, diagnosis, and in...

         - Inflammation, infection, and tissue response basics  

    - Acute vs chronic inflammation patterns   2
    - Necrosis patterns relevant to OB-GYN   3
    - Pathology specimen handling basics   3
    - Thrombosis and embolism concepts   3
    - Wound healing and scar formation   3
- Breast pathology foundations for OB-GYN  

    - Benign breast disease   3
    - Breast cancer basics for generalists   3
    - Breast screening and pathology correlation   4
    - High-risk lesions overview   3
    - Lactation-related breast conditions   3
- Cervical pathology and HPV-mediated disease  

    - CIN/HSIL/LSIL pathologic correlates   3
    - Cytology and histology interpretation basics   3
    - HPV biology and carcinogenesis   3
    - Invasive cervical cancer—histology overview   3
    - Vaginal/vulvar intraepithelial lesions basics   3
- Endometrial pathology and AUB foundations  

    - Benign uterine pathology   3
    - Endometrial carcinoma basics (Type 1 vs Type 2)   3
    - Endometrial hyperplasia classification concepts   2
    - Gestational endometrium and retained products concepts   3
    - Uterine sarcomas overview   3
- Ovarian, tubal, and peritoneal tumors—foundations  

    - Borderline tumors concepts   2
    - Fallopian tube origin hypothesis for HGSC   3
    - GTD pathology overview   3
    - Ovarian tumor classification overview   3
    - Tumor markers basics   3

####  Pharmacology fundamentals (PK/PD and drug handling) 

   61   

         - Pharmacodynamics and receptor theory  

    - Dose–response relationships   4
    - Drug interactions   5
    - Pharmacogenomics (core testables)   5
    - Receptor types and signaling   5
- Pharmacokinetics core concepts  

    - Bioavailability and first-pass metabolism   5
    - Compartment models and parameters   6
    - Organ failure effects on PK   5
    - Redistribution and tissue uptake   4
    - Special populations   5
- Toxicology and adverse drug reactions  

    - Dose-related vs idiosyncratic reactions   4
    - Local anesthetic systemic toxicity (principles)   5
    - Methemoglobinemia and CO toxicity (periop)   4
    - Opioid toxicity and reversal   4

####  Pharmacology, Microbiology &amp; Diagnostic Science (Core) 

   83   

  High-yield medication classes, antimicrobial principles, vaccination and infection concepts, plus di...

         - Diagnostic test interpretation and screening science  

    - Bias and confounding in diagnostic studies   3
    - Critical values and escalation thresholds   3
    - Reference ranges and pregnancy-adjusted labs   3
    - Screening program principles   3
    - Test characteristics and Bayes theorem intuition   3
- Gynecologic pharmacology and contraception hormones  

    - Antibiotics/antifungals commonly used in GYN   4
    - Combined hormonal contraception (CHC) pharmacology   3
    - Emergency contraception   2
    - Menopause therapies   3
    - Progestin-only methods   4
- Medication safety in pregnancy and lactation  

    - Medication safety in breastfeeding   3
    - Peripartum anesthesia/analgesia pharmacology basics   4
    - Pharmacovigilance and counseling resources   4
    - Principles of prescribing in pregnancy   3
    - Teratogenic medication classes (core list)   4
- Microbiology, immunology and infection prevention  

    - Immunization principles for OB-GYN   3
    - Postoperative and postpartum infections   5
    - Pregnancy infections   3
    - STI microbiology essentials   3
    - Vaginal microbiome and common vaginitis   4
- Obstetric medication classes  

    - Diabetes medications in pregnancy   3
    - Hypertension medications in pregnancy   3
    - Thromboprophylaxis and anticoagulants   3
    - Tocolytics and preterm birth meds   4
    - Uterotonics and postpartum hemorrhage meds   3

####  Physics, measurement, mathematics, statistics (foundations) 

   56   

         - Radiation, MRI, and ultrasound physics (foundations)  

    - Ionizing radiation basics   3
    - MRI environment hazards   4
    - Ultrasound fundamentals   4
- Electrical safety and basic electronics  

    - Electrical hazards in OR   5
    - Ohm’s law and power   5
- Flow, pressure, and resistance  

    - Laminar vs turbulent flow   5
    - Poiseuille and Bernoulli principles   5
- Gas laws and vapors relevant to anesthesia  

    - Core gas laws   5
    - Humidity and airway gas conditioning   5
    - Vaporization concepts   5
- Mathematics, dosing, and basic statistics  

    - Data interpretation basics   5
    - Unit conversions and drug calculations   5

####  Physiology &amp; Homeostasis 

   50   

  System physiology emphasizing integration and mechanisms behind common clinical syndromes.

         - Cardiovascular physiology  

    - ECG electrophysiology basics   4
    - Exercise physiology   3
    - Hemodynamics and cardiac output   3
    - Vascular biology   3
- Endocrine physiology  

    - Calcium and bone metabolism   4
    - Glucose homeostasis   4
    - Hypothalamic–pituitary axes   3
    - Thyroid hormone action   3
- Renal physiology &amp; volume regulation  

    - Acid–base renal handling   3
    - Glomerular filtration and hemodynamics   3
    - Tubular handling of electrolytes   3
    - Water balance   3
- Respiratory physiology  

    - Acid–base and respiratory compensation   3
    - Hypoxic pulmonary vasoconstriction   2
    - Lung mechanics   3
    - Ventilation/perfusion and gas exchange   3

####  Reproductive Endocrinology &amp; Menstrual Cycle Physiology 

   45   

  Hormonal regulation across lifespan: puberty, cycle, pregnancy, lactation, menopause; core board phy...

         - Hypothalamic–pituitary–ovarian (HPO) axis regulation  

    - Endometrial cycle and histology   3
    - FSH/LH actions and ovarian steroidogenesis   3
    - GnRH pulsatility and feedback loops   4
    - Ovulation physiology and luteal phase   3
    - Puberty physiology and normal variants   3
- Menopause and perimenopause physiology  

    - Cardiometabolic changes around menopause   3
    - Hormone therapy physiologic rationale and risks   4
    - Ovarian aging and follicular depletion   3
    - Premature ovarian insufficiency (POI) physiology   2
    - Urogenital atrophy (GSM) pathophysiology   3
- Pregnancy endocrine physiology  

    - Calcium/vitamin D and bone metabolism   3
    - hCG, corpus luteum rescue, and placental takeover   2
    - Insulin resistance and metabolic adaptations   3
    - Postpartum endocrine changes   3
    - Thyroid physiology in pregnancy   3

####  Respiratory physiology and acid–base 

   73   

         - Acid–base and electrolytes (physiology foundations)  

    - Anion gap and lactate interpretation   4
    - Henderson–Hasselbalch and bicarbonate buffering   5
    - Key electrolytes for anesthesia   5
    - Stewart/strong ion approach (conceptual)   5
- Control of breathing and perioperative respiratory depression  

    - Central and peripheral chemoreceptors   5
    - Neuromuscular weakness and ventilation   4
    - Ventilatory responses to anesthesia and opioids   4
- Gas exchange: diffusion, V/Q, shunt  

    - Alveolar gas equation and A–a gradient   5
    - CO2 transport and elimination   5
    - Hypoxic pulmonary vasoconstriction (HPV)   4
    - V/Q mismatch vs shunt vs diffusion limitation   5
- Lung volumes, compliance, resistance, and work of breathing  

    - Airway resistance and flow   4
    - Closing capacity and FRC   4
    - PFT patterns for anesthesia   5
    - Static and dynamic compliance   6
    - Ventilation distribution and time constants   3

###  Diagnostic Evaluation 

   212 questions   

####  Clinical Reasoning and Diagnostic Strategy 

   48   

  Differential generation, test selection, and minimizing diagnostic error.

         - Problem representation and differential diagnosis  

    - Avoiding premature closure   5
    - Documentation of uncertainty   4
    - Illness scripts and pivot points   4
    - Syndromic patterns   6
    - Time course and trajectory   5
- Test characteristics and Bayesian application  

    - False positives/negatives and spectrum bias   5
    - Likelihood ratios and post-test probability   5
    - Pretest probability estimation   5
    - Sensitivity/specificity vs predictive values   4
    - Serial testing strategies   5

####  ECG and Cardiac Diagnostic Essentials 

   99   

  ECG interpretation and bedside cardiac risk evaluation.

         - Decision Rules and Diagnostic Pathways  

    - Abdominal pain and appendicitis tools (awareness)   5
    - Chest pain risk tools (conceptual)   5
    - Disposition decision support   5
    - Head injury and C-spine rules   6
    - PE assessment pathways   5
- ECG approach for emergency physicians  

    - Common pitfalls   5
    - Electrolyte and drug effects   5
    - Ischemia and infarction patterns   5
    - Life-threatening conduction abnormalities   5
    - Rate/rhythm/axis and intervals   5
- Imaging Strategy and Interpretation (ED-focused)  

    - Chest radiograph interpretation basics   5
    - CT abdomen/pelvis decision-making   5
    - CT angiography use cases   5
    - Head CT indications and limitations   4
    - MRI access and ED indications   5
- Point-of-Care Ultrasound (POCUS) Fundamentals  

    - Abdominal/vascular POCUS (intro)   5
    - Cardiac POCUS (intro)   5
    - Core POCUS principles and artifacts   5
    - eFAST and trauma applications   4
    - Lung POCUS (intro)   5

####  Laboratory and Bedside Testing 

   65   

  Ordering and interpreting common ED labs and bedside tests with pitfalls.

         - Cardiac biomarkers and chest pain labs  

    - BNP/NT-proBNP use pitfalls   3
    - Co-oximetry and special assays (awareness)   4
    - D-dimer: when not to order   4
    - Point-of-care glucose and ketones   4
    - Troponin interpretation strategy   5
- Core ED labs interpretation  

    - ABG/VBG and lactate   5
    - BMP/CMP patterns   5
    - CBC patterns   5
    - Coagulation studies   5
    - Urinalysis and pregnancy testing   5
- Microbiology and infectious testing  

    - CSF studies (intro)   4
    - Cultures and timing   4
    - Inflammatory markers pitfalls   4
    - Respiratory viral testing and implications   4
    - STI testing basics   4

###  Emergency Care Foundations 

   297 questions   

####  ED Workflow, Safety, and Core Task Domains 

   119   

  Core physician tasks: consultation, disposition, documentation, teamwork, and patient safety across...

         - Consultation, escalation, and interdepartmental coordination  

    - Consultant follow-up and contingency plans   4
    - Managing disagreement and delays   5
    - Structured communication (SBAR/I-PASS)   5
    - Transfer and accepting facility coordination   3
    - When to consult   5
- Diagnostic ordering and resource stewardship  

    - Follow-up of pending results   4
    - Pretest probability thinking   5
    - Radiation/contrast risk communication   4
    - Stepwise testing strategies   5
    - Time-critical testing   7
- Disposition planning and transitions of care  

    - Against-medical-advice (AMA) processes   5
    - Discharge readiness assessment   5
    - Handover within ED and to inpatient teams   6
    - Observation vs admission vs discharge   4
    - Return precautions and safety-netting   5
- Documentation and medicolegal defensibility (foundational)  

    - Communication documentation   6
    - Medical decision-making documentation   5
    - Privacy basics (ED-relevant)   4
    - Procedure documentation essentials   5
    - Results management   5
- Human factors, teamwork, and crisis resource management (CRM) basics  

    - Closed-loop communication   4
    - Debriefing fundamentals   5
    - Error types and mitigation   5
    - Handover safety in a busy ED   4
    - Team roles and leadership behaviors   4

####  Initial Assessment and Triage 

   67   

  Approach to undifferentiated presentations, acuity stratification, and immediate stabilization prior...

         - ED triage and acuity stratification  

    - Crowding-aware risk management   4
    - High-risk symptoms requiring immediate evaluation   5
    - Re-triage and dynamic acuity   3
    - Triage categories and time-critical flags   5
    - Vital signs interpretation and pitfalls   4
- Primary survey (ABCDE) and early stabilization  

    - Airway assessment and immediate maneuvers   6
    - Breathing assessment   6
    - Circulation assessment   4
    - Disability/neurologic quick checks   5
    - Exposure/environment control   3
- Secondary survey and focused evaluation  

    - Clinical monitoring and escalation   4
    - Focused history frameworks   4
    - Focused physical exam techniques   4
    - Pain assessment and reassessment   5
    - Red flags and risk modifiers   5

####  Symptom-Based Approaches (Foundational) 

   111   

  Structured initial differentials and first-pass workup for common undifferentiated complaints.

         - Fever and suspected infection approach  

    - Antipyretics and symptomatic care   3
    - Pitfalls   4
    - Sepsis recognition and early actions   5
    - Source identification strategy   4
    - Special populations considerations   5
- Syncope and near-syncope initial approach  

    - High-risk etiologies   5
    - History/exam essentials   5
    - Pitfalls   4
    - Risk stratification and disposition   4
    - Testing strategy   4
- Undifferentiated abdominal pain approach  

    - Analgesia, antiemetics, and reassessment   3
    - Disposition and return precautions   5
    - History and location-based differentials   5
    - Imaging and lab strategy (conceptual)   5
    - Surgical abdomen red flags   5
- Undifferentiated chest pain approach  

    - Initial testing and prioritization   5
    - Must-not-miss diagnoses   5
    - Non-cardiac etiologies overview   4
    - Pitfalls and cognitive errors   5
    - Risk stratification and disposition concepts   5
- Undifferentiated dyspnea approach  

    - Bedside assessment integration   4
    - Disposition decisions   4
    - Initial testing and treatment bundles   5
    - Life threats and immediate stabilization   5
    - Pitfalls   3

###  Organ System Emergencies 

   874 questions   

####  Allergy, Dermatology, Rheumatology, and Immune-Mediated Emergencies 

   105   

  Common allergic reactions, severe skin disease, and inflammatory joint/autoimmune presentations.

         - Rheumatologic emergencies and back pain red flags  

    - Acute gout/pseudogout management   5
    - Autoimmune flares (SLE/vasculitis) overview   5
    - Cauda equina/spinal epidural abscess awareness   4
    - Disposition and safety net   4
    - Temporal arteritis awareness   4
- Severe cutaneous adverse reactions (SCAR)  

    - Consultation and disposition   4
    - Differential diagnosis   5
    - Initial management   4
    - Pitfalls   4
    - SJS/TEN recognition   4
- Anaphylaxis and severe allergic reactions  

    - Adjuncts and limitations   4
    - Diagnosis and grading   5
    - Observation and discharge planning   4
    - Pitfalls   4
    - Treatment   4
- Angioedema (histaminergic vs bradykinin)  

    - Airway management strategy   4
    - Clinical differentiation   5
    - Disposition   3
    - Medication therapy   5
    - Pitfalls   3
- Septic arthritis and hot swollen joint  

    - Differential diagnosis   6
    - Disposition   3
    - Empiric antibiotics and consultation   4
    - Special populations   5
    - Workup strategy   3

####  Behavioral Health, Addiction, ENT/Ophthalmology 

   114   

  Psychiatric emergencies, intoxication/withdrawal syndromes, and common ENT/eye emergencies.

         - ENT emergencies (core)  

    - Dental emergencies   6
    - Epistaxis management   4
    - Foreign body in nose/ear   4
    - Otitis externa/media and mastoiditis awareness   6
    - Peritonsillar abscess and deep neck infection awareness   5
- Agitation, psychosis, and behavioral emergencies  

    - Chemical sedation strategies (core)   6
    - De-escalation and environment   4
    - Disposition   4
    - Medical causes of agitation   6
    - Restraints and monitoring   4
- Ophthalmologic emergencies (core)  

    - Acute vision loss   4
    - Corneal abrasion/foreign body   5
    - Disposition and ophthalmology consultation triggers   4
    - Eye exam essentials   4
    - Red eye differential (dangerous causes)   5
- Substance intoxication and withdrawal (core)  

    - Alcohol withdrawal   4
    - Disposition and counseling   4
    - Opioid intoxication and overdose   4
    - Sedative-hypnotic overdose/withdrawal   4
    - Stimulant intoxication   5
- Suicidal ideation and self-harm risk assessment  

    - Capacity and involuntary hold concepts   4
    - Disposition and safety planning   5
    - Immediate safety and medical stabilization   4
    - Pitfalls   4
    - Risk assessment components   5

####  Cardiovascular Emergencies 

   114   

  Time-critical cardiac and vascular syndromes and symptom-based evaluation.

         - Acute coronary syndrome (ACS) and ischemic chest pain  

    - Biomarkers and serial strategy   5
    - Clinical presentations and atypical ACS   3
    - Disposition and reperfusion pathways   6
    - ECG-based diagnosis and pitfalls   5
    - Initial ED management   5
- Acute heart failure and cardiomyopathy syndromes  

    - Bedside assessment and imaging   4
    - Cardiogenic shock recognition   4
    - Differential diagnosis of dyspnea   5
    - Disposition considerations   4
    - Treatment pathways   3
- Dysrhythmias and palpitations  

    - Approach to tachyarrhythmia   5
    - Atrial fibrillation/flutter   4
    - Bradyarrhythmias   6
    - SVT   5
    - Ventricular arrhythmias   5
- Hypertensive crisis and vascular catastrophes  

    - Acute limb ischemia   4
    - Aneurysm rupture recognition   4
    - Aortic syndromes   4
    - BP reduction principles by syndrome   4
    - Hypertensive emergency syndromes   4
- Syncope and presyncope  

    - Cardiac syncope red flags   7
    - Neurogenic and reflex syncope   3
    - Orthostatic and volume-related syncope   5
    - Pitfalls   5
    - Testing and disposition   5

####  Endocrine and Metabolic Emergencies 

   65   

  Diabetes emergencies, thyroid/adrenal crises, and metabolic derangements.

         - Thyroid and adrenal emergencies  

    - Adrenal crisis   4
    - Disposition   3
    - Myxedema coma   4
    - Pituitary apoplexy (awareness)   3
    - Thyroid storm   5
- Electrolyte disorders as primary ED problem  

    - Acid-base disorders presentation patterns   4
    - Calcium/magnesium disorders   5
    - Disposition and monitoring   5
    - Hyponatremia/hypernatremia management principles   3
    - Potassium disorders   5
- Hypoglycemia and severe hyperglycemia  

    - Counseling and follow-up   4
    - Diabetes devices and complications (awareness)   5
    - DKA/HHS overview (see resuscitation)   5
    - Hyperglycemia without DKA   5
    - Hypoglycemia recognition and treatment   5

####  Gastrointestinal, Hepatobiliary, and Surgical Emergencies 

   108   

  Abdominal pain syndromes, GI bleeding, hepatobiliary and pancreatitis, and bowel emergencies.

         - Acute abdominal pain and peritonitis  

    - Analgesia and antiemetics   5
    - Common surgical diagnoses (overview)   6
    - Disposition and consultation triggers   4
    - Surgical abdomen recognition   5
    - Workup strategy   3
- Bowel obstruction and ischemia  

    - Disposition and time-critical pitfalls   5
    - Ischemic colitis (overview)   4
    - Large bowel obstruction and volvulus (awareness)   5
    - Mesenteric ischemia   3
    - Small bowel obstruction (SBO)   4
- Gastrointestinal bleeding  

    - Pharmacotherapy   4
    - Pitfalls   4
    - Resuscitation priorities   4
    - Risk stratification and disposition   5
    - Upper vs lower GI bleed differentiation   3
- Hepatobiliary and pancreatic emergencies  

    - Acute liver failure and hepatic encephalopathy (overview)   5
    - Acute pancreatitis   4
    - Biliary colic vs cholecystitis   4
    - Cholangitis   3
    - Disposition and complications   5
- Nausea, vomiting, diarrhea, and dehydration  

    - Cannabinoid hyperemesis and cyclic vomiting (awareness)   4
    - Dangerous causes to exclude   4
    - Disposition   5
    - Infectious gastroenteritis and foodborne illness   5
    - Rehydration strategies   5

####  Hematologic/Oncologic and Infectious Syndromes 

   65   

  High-yield ED hematology, oncology emergencies, and key infectious syndromes.

         - Oncologic emergencies  

    - Cancer-associated thrombosis and PE risk   3
    - Hyperviscosity syndrome awareness   4
    - Neutropenic fever   4
    - Spinal cord compression and cauda equina (overlap)   4
    - Tumor lysis syndrome (TLS) awareness   4
- Anemia, thrombocytopenia, and bleeding disorders  

    - Coagulopathy and anticoagulant complications   5
    - Sickle cell disease emergencies   4
    - Symptomatic anemia management   5
    - Thrombocytopenia approach   5
    - Thrombotic microangiopathy awareness   3
- Sepsis syndromes and source-specific emergencies  

    - CNS infection   4
    - Endocarditis awareness   5
    - Pneumonia/UTI/abdominal sepsis   6
    - Skin/soft tissue sepsis and necrotizing infection   4
    - Special infectious threats (board-level)   5

####  Neurologic Emergencies 

   114   

  Stroke, headache, seizure, and other time-critical neurologic presentations.

         - Vertigo, dizziness, and ataxia  

    - Benign peripheral syndromes   5
    - Central vs peripheral differentiation   5
    - Disposition   5
    - Imaging decisions   5
    - Symptomatic treatment   3
- Acute ischemic stroke and TIA  

    - Initial ED workup   4
    - Pitfalls   4
    - Recognition and last-known-well   6
    - Reperfusion therapy pathways (conceptual)   5
    - TIA risk and disposition   4
- Headache emergencies  

    - Dangerous secondary headache red flags   5
    - Disposition and follow-up   4
    - Meningitis/encephalitis suspicion   4
    - Primary headache management   4
    - Subarachnoid hemorrhage evaluation strategy   4
- Intracranial hemorrhage and traumatic brain injury (medical overlap)  

    - Disposition   4
    - ICH/SAH presentations   7
    - ICP/herniation management (intro)   4
    - Imaging and consultation   6
    - Immediate management   5
- Seizures and status epilepticus  

    - Alcohol withdrawal seizures   4
    - Disposition   4
    - Eclampsia seizure awareness   4
    - First seizure evaluation   5
    - Status epilepticus algorithm (core)   4

####  Renal, Urologic, and Reproductive-Urologic Emergencies 

   83   

  Renal colic, infection, retention/obstruction, and acute scrotal pathology.

         - Acute scrotum and testicular emergencies  

    - Disposition   5
    - Epididymitis treatment basics   4
    - Initial management   3
    - Testicular torsion recognition   5
    - Ultrasound and differential   5
- Renal colic and ureteral obstruction  

    - Analgesia and antiemetics   5
    - Diagnosis and imaging strategy   3
    - Disposition   5
    - Infected obstructed system recognition   3
    - Medical expulsive therapy (awareness)   3
- Urinary retention and obstructive uropathy  

    - Bladder decompression   3
    - Complications   5
    - Disposition   4
    - Recognition and causes   4
    - When to image/consult   5
- Urinary tract infection and pyelonephritis  

    - Antibiotic selection principles   4
    - Catheter-associated infections   4
    - Cystitis vs pyelonephritis   4
    - Disposition   5
    - Sepsis and complications   4

####  Respiratory Emergencies 

   106   

  Common and life-threatening pulmonary presentations including obstructive, infectious, and vascular...

         - Upper airway infections and obstruction (ENT overlap)  

    - Angioedema/anaphylaxis airway issues   4
    - Croup/epiglottitis patterns (awareness across ages)   5
    - Disposition   4
    - Foreign body aspiration   2
    - Smoke inhalation and airway edema   4
- Asthma and COPD exacerbations  

    - Disposition and relapse prevention   5
    - ED treatment escalation   4
    - Pitfalls   4
    - Severity assessment and failure markers   4
    - Ventilation considerations (conceptual)   5
- Pneumonia, pleural disease, and respiratory infections  

    - Antibiotics and supportive care   4
    - CAP and atypical pneumonia presentations   6
    - Diagnostics and severity assessment   4
    - Disposition   4
    - Pleural effusion/empyema recognition   4
- Pneumothorax and acute pleural emergencies  

    - Complications and recurrence counseling   4
    - Diagnosis methods   4
    - Disposition   4
    - Management options   5
    - Recognition   4
- Pulmonary embolism and pulmonary vascular emergencies  

    - Anticoagulation and reperfusion (conceptual)   5
    - Disposition and follow-up   4
    - Imaging choices   4
    - Massive/submassive PE recognition   4
    - Risk assessment and pretest probability   5

###  Procedural Skills 

   380 questions   

####  Airway and Ventilation Procedures (Core) 

   92   

  Basic airway management skills expected of EM trainees.

         - Surgical airway (recognition and readiness)  

    - Anatomy and landmarks   4
    - Complications   4
    - Post-airway care   5
    - Technique overview (board-level)   4
    - When to perform   6
- Bag-valve-mask ventilation (BVM)  

    - Airway adjuncts   3
    - Complications and prevention   3
    - Indications and preparation   5
    - Technique and optimization   4
    - Troubleshooting   5
- Endotracheal intubation (fundamentals)  

    - Basic RSI sequence (conceptual)   6
    - Common complications management   5
    - Confirmation and securing   3
    - Equipment and setup   5
    - Indications and planning   7
- Supraglottic airway placement  

    - Complications   4
    - Contraindications/limitations   6
    - Indications and device selection   4
    - Insertion technique   5
    - Ventilation strategy and leak management   4

####  Orthopedic and Diagnostic Procedures (Core) 

   111   

  Splinting, reductions, LP, and other foundational ED procedures.

         - Lumbar puncture (LP)  

    - Complications   5
    - Contraindications and pre-imaging decisions   5
    - CSF interpretation basics   4
    - Indications   5
    - Technique basics   4
- Thoracic procedures (intro)  

    - Analgesia and sedation considerations   4
    - Chest tube thoracostomy (basic awareness)   4
    - Needle decompression (recognition and basics)   4
    - Post-procedure imaging and monitoring   4
    - Thoracentesis (basic awareness)   3
- Joint reductions (foundational)  

    - Ankle and patellar dislocations (awareness)   4
    - Complications   4
    - Finger dislocation reduction   4
    - Hip dislocation (recognition and urgency)   3
    - Shoulder dislocation reduction   5
- Procedural sedation (core practice)  

    - Airway rescue and adverse events   4
    - Medication choices (core)   5
    - Monitoring and staffing   5
    - Patient selection and risk assessment   5
    - Recovery and discharge criteria   6
- Splinting and immobilization  

    - Common splints   6
    - Discharge instructions   5
    - Indications and principles   4
    - Neurovascular checks   4
    - Splint complications   5

####  Vascular Access and Infusion Procedures 

   87   

  IV/IO access and foundational central/arterial concepts for emergency care.

         - Arterial puncture/line (awareness)  

    - Common sites and collateral flow   5
    - Complications   3
    - Documentation   5
    - Indications   4
    - Technique basics (conceptual)   5
- Central venous access (foundational)  

    - Complications   5
    - Indications   4
    - Post-procedure confirmation   4
    - Sites and anatomic considerations   4
    - Ultrasound guidance principles (intro)   4
- Intraosseous (IO) access  

    - Analgesia for awake IO   3
    - Common insertion sites   4
    - Complications   5
    - Indications and contraindications   4
    - Technique and confirmation   4
- Peripheral IV access and troubleshooting  

    - Aseptic technique and infection prevention   5
    - Complications   4
    - Difficult IV strategies   5
    - IV medication administration safety   5
    - Site selection and catheter choice   5

####  Wound, Skin, and Soft Tissue Procedures 

   90   

  Local anesthesia, wound repair, and abscess management.

         - Foreign body removal (soft tissue)  

    - Aftercare   5
    - Complications   4
    - Indications and imaging   4
    - Special locations   4
    - Technique principles   4
- Abscess incision and drainage (I&amp;D)  

    - Complications   5
    - Culture and antibiotics decisions   4
    - Differentiating cellulitis vs abscess   5
    - Disposition and follow-up   4
    - Technique   4
- Laceration evaluation and repair  

    - Aftercare   5
    - Closure techniques   5
    - Irrigation and debridement   4
    - Special wounds   6
    - Wound assessment   5
- Local and regional anesthesia (core)  

    - Digital block and end-artery considerations   4
    - Field block and infiltration technique   5
    - LAST recognition and initial management   4
    - Local anesthetic agents and dosing   5
    - Procedural documentation and consent   4

###  Professional Practice 

   276 questions   

####  Communication, Teamwork, and Patient-Centered Care 

   26   

  Core communication behaviors, empathy under pressure, and effective teamwork.

         - Patient-centered communication in the ED  

    - Agenda setting and expectation management   3
    - Communicating uncertainty and risk   3
    - Cross-cultural communication   3
    - Delivering difficult news (foundational)   2
    - Managing challenging interactions   3
- Teamwork and leadership basics  

    - Closed-loop communication   2
    - Conflict management basics   2
    - Debriefing and reflective practice (intro)   2
    - Handover and transitions   3
    - Situational awareness and workload management   3

####  Ethics, Consent, and Legal Interfaces 

   39   

  Foundational professional obligations, capacity, consent, and ED medicolegal responsibilities.

         - Consent and decision-making capacity  

    - Capacity assessment framework   2
    - Informed consent in the ED   3
    - Refusal of care and AMA discharge   2
    - Resuscitation status and goals-of-care basics   3
    - Surrogate decision-makers and minors   4
- Documentation Standards and Risk Management  

    - Avoiding biased/stigmatizing language   2
    - Handover documentation   3
    - Medical decision making (MDM) clarity   3
    - Procedure documentation   2
    - Results follow-up and callbacks   3
- Mandatory reporting and safeguarding duties  

    - Child abuse reporting   2
    - Death certification and coroner/ME interface (awareness)   2
    - Fitness to drive/duty to warn (contextual awareness)   2
    - Reportable infectious diseases (awareness)   2
    - Sexual assault and IPV documentation   4

####  Ethics, law, and professional responsibilities 

   90   

  Consent/assent, confidentiality, decision-making standards, safeguarding/reporting obligations, and...

         - Research literacy and statistics for clinicians  

    - Critical appraisal of medical literature   3
    - Data safety and privacy (overview)   3
    - Ethics in research and publication   3
    - Interpreting common statistical outputs   4
    - Practice improvement through audit (overview)   3
- Child protection duties and reporting (core professional practice)  

    - Communication with caregivers in suspected abuse   2
    - Mandatory reporting principles   3
    - Medical mimics and avoiding diagnostic error   4
    - Professional boundaries and self-care after difficult cases   3
    - Recognizing possible abuse and neglect (overview)   3
- Communication skills and professionalism  

    - Conflict resolution and teamwork   3
    - Cultural humility and cross-cultural communication   3
    - Delivering difficult news and serious illness communication   3
    - Documentation and medicolegal quality   3
    - Professionalism lapses and remediation awareness   3
- Confidentiality and privacy in adolescent care  

    - Creating confidential time in visits   3
    - Electronic communication professionalism   3
    - Information sharing with schools and agencies   2
    - Mandatory disclosure exceptions   2
    - Sensitive services (sexual health, mental health, substance use)   2
- Consent, assent, and capacity in pediatrics  

    - Mature minor and emancipated minor concepts (jurisdiction-dependent)   3
    - Parental permission vs child assent   4
    - Refusal of treatment and best interest standard   3
    - Research consent in minors (overview)   3
    - Shared decision-making and informed consent elements   4
- Quality, safety, and clinical governance  

    - Error disclosure and apology   3
    - Infection prevention and antimicrobial stewardship (professional practice)   3
    - Medication and diagnostic safety in pediatrics   3
    - Patient safety fundamentals   3
    - Quality improvement (QI) methods   3

####  Ethics, Law, Consent &amp; Safeguarding 

   75   

  Professional standards for consent, confidentiality, capacity, boundaries, documentation, reporting,...

         - Confidentiality, privacy, and mandated reporting concepts  

    - Adolescent confidentiality (principles)   2
    - Confidentiality principles in sexual and reproductive care   3
    - Human trafficking awareness   3
    - Mandatory reporting (conceptual, jurisdiction-dependent)   3
    - Safeguarding: IPV and sexual violence   3
- Evidence-Based Practice, Research Literacy &amp; Guideline Use  

    - Applying guidelines to individuals   3
    - Clinical ethics in evidence translation   2
    - Critical appraisal of clinical studies   3
    - Research integrity and publication ethics   3
    - Statistics commonly tested   3
- Informed consent and refusal of care  

    - Consent for learners and sensitive exams   4
    - Consent in emergencies   2
    - Elements of informed consent   4
    - Procedural consent specifics   4
    - Refusal of recommended treatment   4
- Patient Safety, Quality Improvement, and Risk Management  

    - Clinical governance and incident reporting   3
    - Medicolegal risk reduction   3
    - Obstetric safety bundles (conceptual)   2
    - Quality improvement methods   3
    - Safety culture and error science   3
- Professionalism, Teamwork, Education &amp; Wellbeing  

    - Clinician wellbeing and burnout prevention   3
    - Equity, diversity, and respectful care   4
    - Interprofessional teamwork and communication   3
    - Professional boundaries and social media   2
    - Teaching and supervision (clinical educator basics)   3

####  Quality, Safety, and Systems (Foundational) 

   46   

  Basics of patient safety, quality improvement, infection control, and ED operations awareness.

         - ED operations and flow (intro)  

    - Consultation pathways and transfer   3
    - Discharge processes and health system navigation   3
    - Equity and access in ED care   3
    - Handoffs and staffing considerations   3
    - Throughput basics   4
- Professionalism, wellness, and boundaries  

    - Ethical prescribing and controlled substances   3
    - Fatigue, burnout, and error risk   3
    - Professional boundaries and social media awareness   2
    - Professional conduct and accountability   4
    - Teaching and supervision basics   3
- Patient safety fundamentals  

    - Diagnostic error mitigation   3
    - High-risk medications and dosing safety   2
    - Incident reporting and learning systems   3
    - Infection prevention and PPE   3
    - Violence prevention and workplace safety   4

###  Resuscitation And Stabilization 

   388 questions   

####  Airway and Breathing Emergencies 

   110   

  Recognition and immediate management of respiratory failure and airway threats.

         - Acute asthma and COPD exacerbation stabilization  

    - Adjuncts and escalation   4
    - Disposition and relapse prevention   5
    - Initial ED therapy   5
    - Severity assessment   4
    - Ventilation strategy (intro)   6
- Oxygenation and ventilation fundamentals in resuscitation  

    - Monitoring in respiratory distress   4
    - Oxygen delivery escalation   5
    - Peri-intubation risk reduction (foundational)   4
    - Rapid reassessment and troubleshooting   5
    - Ventilation support escalation   4
- Pulmonary edema and acute heart failure stabilization  

    - Adjunct testing while stabilizing   4
    - Disposition and monitoring   4
    - Immediate management   4
    - Recognition and differential   5
    - Ventilatory failure escalation   5
- Upper airway obstruction and anaphylaxis/angioedema stabilization  

    - Adjunct medications and limitations   4
    - Airway planning and backup   4
    - Early recognition of impending obstruction   5
    - Immediate treatment   4
    - Observation and biphasic risk   4
- Ventilatory failure and post-intubation stabilization (core)  

    - Initial ventilator settings (intro)   4
    - Ongoing reassessment   5
    - Post-intubation confirmation and troubleshooting   4
    - Post-intubation hypotension management   3
    - Sedation/analgesia after intubation   5

####  Circulatory Collapse and Shock 

   117   

  Cardiac arrest, peri-arrest dysrhythmias, and shock state stabilization.

         - Hypertensive emergencies (stabilization)  

    - BP reduction principles   5
    - Common IV agents (conceptual)   4
    - Hypertensive urgency and outpatient follow-up   4
    - Recognizing end-organ injury   5
    - Secondary causes awareness   4
- Bradycardia and tachycardia with instability  

    - Atrial fibrillation/flutter with RVR   5
    - Bradycardia management   4
    - Narrow-complex tachycardia management   5
    - Recognition of unstable features   5
    - Wide-complex tachycardia management   4
- Cardiac arrest (BLS/ACLS principles)  

    - Airway and ventilation during arrest   4
    - Defibrillation and rhythm management   5
    - High-quality CPR   4
    - Post-ROSC care (initial)   4
    - Reversible causes (Hs &amp; Ts) approach   7
- Sepsis recognition and early ED management  

    - Antibiotics and fluids   5
    - Disposition and escalation   5
    - Sepsis screening and severity assessment   5
    - Source identification and initial diagnostics   5
    - Vasoactive support initiation   4
- Shock states: rapid classification and initial management  

    - Cardiogenic shock   5
    - Hypovolemic/hemorrhagic shock   5
    - Obstructive shock   5
    - Septic shock initial bundle   4
    - Undifferentiated shock approach   5

####  Neurologic and Metabolic Emergencies 

   118   

  Rapid stabilization of altered mental status, seizures, endocrine crises, and temperature-related in...

         - Altered mental status (AMS): immediate stabilization  

    - Agitation safety and de-escalation   5
    - Dangerous causes framework   6
    - Diagnostics while stabilizing   5
    - Disposition and reassessment   4
    - Immediate reversible checks   5
- DKA/HHS and severe dysglycemia stabilization  

    - Bicarbonate and phosphate (selective)   4
    - Disposition and complication monitoring   5
    - Fluid resuscitation principles   4
    - Insulin therapy and potassium management   4
    - Recognition and initial labs   4
- Electrolyte emergencies causing instability  

    - Hyperkalemia stabilization   6
    - Hypernatremia and dehydration   6
    - Hypocalcemia/hypercalcemia emergencies   4
    - Hypomagnesemia and torsades   5
    - Hyponatremia with neurologic symptoms   4
- Status epilepticus and seizure emergencies  

    - Febrile seizures and pediatric considerations   4
    - Initial stabilization and first-line therapy   4
    - Postictal management and evaluation   5
    - Second-line antiseizure therapy (core awareness)   4
    - Seizure differential and triggers   5
- Temperature emergencies stabilization  

    - Drowning and immersion injury (initial)   5
    - Frostbite and cold injury (initial)   5
    - Heat stroke and severe hyperthermia   5
    - Hypothermia and cardiac instability   5
    - Malignant hyperthermia/NMS/serotonin syndrome awareness   5

####  Trauma Resuscitation (Core) 

   43   

  Time-critical trauma stabilization principles and immediate hemorrhage control.

         - Massive hemorrhage and transfusion in trauma (core)  

    - Balanced resuscitation principles   4
    - Coagulopathy, hypothermia, acidosis triad   5
    - Disposition and definitive care coordination   4
    - Recognition of hemorrhagic shock   5
    - TXA and hemostatic adjuncts (awareness)   3
- Primary survey and trauma team leadership (ATLS principles)  

    - Airway with C-spine protection   5
    - Breathing and chest injury recognition   5
    - Circulation and hemorrhage control   5
    - Disability and rapid neuro assessment   3
    - Exposure and hypothermia prevention   4

###  Special Populations 

   396 questions   

####  Advanced Special Population Integration 

   14   

  Category placeholder to maintain structure; see 'Special Populations (Advanced)' domain set above.

         - Integrated advanced special populations review  

    - Critically ill neonate/child   3
    - Geriatric frailty and anticoagulation complications   3
    - High-risk pregnancy emergencies   3
    - Immunocompromised/oncology emergencies   3
    - Palliative and end-of-life care   2

####  Cultural, linguistic, and refugee mental health 

   17   

  Culturally safe care, interpreter use, trauma and displacement, and diagnostic adaptations.

         - Refugee trauma and complex needs  

    - Care coordination with social/legal supports   5
    - Pre-, peri-, post-migration stressors   4
- Cultural formulation and culturally bound expressions  

    - Eliciting explanatory models   5
    - Interpreter-mediated assessments   3

####  Geriatrics and Frailty (Core) 

   31   

  Atypical presentations, falls, delirium, polypharmacy, and disposition safety in older adults.

         - Atypical presentations and geriatric assessment  

    - Atypical infection/ACS presentations   3
    - Delirium recognition   3
    - Disposition safety   3
    - Frailty and functional assessment   4
    - Polypharmacy and adverse drug events   3
- Falls and trauma in older adults  

    - Disposition and safeguarding   3
    - Head injury on anticoagulants   3
    - Hip and pelvic fractures   4
    - Rib fractures and respiratory compromise   2
    - Syncope vs mechanical fall differentiation   3

####  High-Risk and Under-Served Groups (Advanced) 

   34   

  Clinical care tailored to specific physiologic and social contexts.

         - Care of patients with advanced cancer and comorbidities  

    - Complications of therapy affecting other organs   4
    - Decision-making under limited prognosis   2
    - Infection risk management   4
    - Transitions to hospice   3
- Patients with serious mental illness  

    - Capacity and adherence challenges   3
    - Delirium vs psychiatric symptom overlap   2
    - Metabolic monitoring for antipsychotics   2
    - Suicide risk in medical illness   3
- Patients with substance use disorders and complex illness  

    - Hospital-based addiction care   3
    - Infections related to injection drug use   3
    - Pain management with OUD   3
    - Trauma-informed care   2

####  Immunocompromised Patients (Core) 

   26   

  Oncology, transplant, HIV, and iatrogenic immunosuppression presentations and ED priorities.

         - Oncologic and therapy-related complications (intro)  

    - Disposition   2
    - Immunotherapy adverse events awareness   3
    - Spinal cord compression awareness   3
    - Thrombosis/PE risk in cancer   3
    - Tumor lysis syndrome awareness   2
- Fever in immunocompromised patients  

    - Disposition   2
    - HIV and opportunistic infection awareness   3
    - Neutropenic fever   2
    - Steroid/biologic immunosuppression   3
    - Transplant patient infection risk   3

####  Intellectual disability, autism, and communication differences 

   18   

  Adapting assessment and treatment for neurodevelopmental and cognitive differences across lifespan.

         - Challenging behavior and risk management  

    - Positive behavior support planning   4
    - Psychotropic use: target symptoms and monitoring   3
- Diagnostic overshadowing and medical contributors  

    - Communication-adapted interviewing   6
    - Pain, constipation, seizures, sleep problems   5

####  LGBTQ+ and gender-related mental health care 

   16   

  Affirming assessment, minority stress, gender dysphoria-related care principles, and psychiatric com...

         - Gender dysphoria care principles (within psychiatrist scope)  

    - Assessment and comorbidity evaluation   4
    - Collaborative care with gender-affirming services   5
- Minority stress and stigma-related mental health risks  

    - Assessment of discrimination, violence, and support   4
    - Suicide risk and protective interventions   3

####  Pediatrics 

   80   

  Age-specific assessment, stabilization, and high-risk pediatric presentations.

         - Febrile infant and pediatric sepsis (foundational)  

    - Disposition   4
    - Empiric antibiotics   5
    - Initial evaluation   4
    - Pitfalls   3
    - Risk stratification concepts by age   4
- Pediatric assessment and physiology essentials  

    - Age-adjusted vitals and shock recognition   4
    - Fever and serious bacterial infection risk   5
    - Pain assessment and analgesia   3
    - Pediatric airway differences   4
    - Safeguarding basics   5
- Pediatric dehydration and GI illness  

    - Assessment of dehydration   4
    - Disposition   3
    - Electrolyte derangements awareness   4
    - Oral rehydration therapy (ORT)   4
    - When to suspect surgical abdomen   5
- Pediatric respiratory distress syndromes  

    - Bronchiolitis   4
    - Croup   4
    - Disposition and family counseling   3
    - Foreign body aspiration   3
    - Pediatric asthma   5

####  Perinatal and reproductive psychiatry 

   16   

  Assessment and treatment planning around pregnancy, postpartum, lactation, and reproductive transiti...

         - PMDD and reproductive transitions  

    - Diagnosis and treatment overview   4
- Perinatal mood and anxiety disorders  

    - Medication risk-benefit counseling   4
    - Safety planning and mother-infant considerations   3
    - Screening and differential diagnosis   5

####  Pregnancy and Gynecologic Emergencies (Core) 

   86   

  Physiologic changes, early pregnancy complications, and common OB/GYN emergencies in the ED.

         - Second/third-trimester bleeding (overview)  

    - Disposition and transfer   4
    - Pitfalls   4
    - Placenta previa/abruption awareness   5
    - Postpartum hemorrhage awareness   5
    - Preterm labor awareness   6
- First-trimester bleeding and ectopic pregnancy  

    - Complications and pitfalls   5
    - Disposition   4
    - Initial evaluation   4
    - Management pathways   5
    - Ultrasound interpretation (conceptual)   4
- Hypertensive disorders of pregnancy (core)  

    - BP management principles   3
    - Disposition   3
    - HELLP syndrome awareness   3
    - Magnesium sulfate therapy   3
    - Preeclampsia/eclampsia recognition   5
- Pregnancy physiology and ED implications  

    - Cardiovascular/respiratory changes   5
    - Disposition and follow-up   4
    - Laboratory and imaging considerations   6
    - Resuscitation modifications   4
    - Trauma considerations   4

####  Safeguarding, Social Determinants, and Vulnerable Groups 

   42   

  Discharge planning and safety for patients with social vulnerability or safeguarding needs.

         - Homelessness, substance use, and high-utilization care  

    - Behavioral health comorbidity   4
    - Documentation and ethical considerations   2
    - Harm reduction in ED   2
    - Linkage to care and follow-up   3
    - Medical risks and barriers   3
- Patients with disabilities and communication barriers  

    - Capacity and consent considerations   2
    - Communication accommodations   2
    - Discharge planning   2
    - Pitfalls   3
    - Safeguarding and abuse risk   2
- Domestic violence and sexual assault (core)  

    - Forensic pathways awareness   3
    - Mandatory reporting (contextual)   3
    - Medical care essentials   4
    - Safety planning and resources   4
    - Trauma-informed care   3

####  Severe psychosocial vulnerability and marginalized contexts 

   16   

  Homelessness, incarceration, HIV, chronic pain, and other contexts requiring adapted and equitable c...

         - HIV and neuropsychiatric complications  

    - Depression, cognitive impairment, medication interactions   5
- Incarcerated individuals and reentry planning (overview)  

    - Continuity of care and medication access   3
- Chronic pain and opioid risk  

    - Integrated pain and mental health care   4
- Homelessness and serious mental illness  

    - Engagement and harm reduction   4

###  Toxicology And Environmental 

   198 questions   

####  High-Yield Pharmaceutical and Drug Exposures 

   131   

  Common ingestions and toxidromes frequently tested in EM boards.

         - Beta-blocker and calcium channel blocker toxicity  

    - Disposition   3
    - Initial management   5
    - Pitfalls   4
    - Recognition and ECG findings   4
    - Specific therapies (awareness)   5
- SSRIs, serotonin syndrome, and neuroleptic malignant syndrome  

    - Differential diagnosis   4
    - Disposition   5
    - NMS recognition   5
    - Serotonin syndrome recognition   4
    - Treatment   5
- Acetaminophen toxicity  

    - Disposition   5
    - Pitfalls   5
    - Risk assessment by timing and dose   5
    - Treatment   5
    - Workup   5
- Opioids and sedative-hypnotics  

    - Benzodiazepine overdose   5
    - Disposition   4
    - GHB and other club drugs (awareness)   3
    - Naloxone strategies   5
    - Opioid overdose recognition   4
- Salicylate poisoning  

    - Clinical pattern and mixed acid-base   5
    - Diagnostics   4
    - Dialysis indications awareness   4
    - Disposition   4
    - Treatment   4
- Tricyclic antidepressants (TCA) and sodium-channel blockers  

    - Clinical and ECG features   4
    - Disposition   3
    - Pitfalls   5
    - Refractory shock/arrhythmia rescue (awareness)   4
    - Treatment   4

####  Toxicology Approach and Antidotes 

   67   

  Toxidromes, decontamination, antidote principles, and coordination with poison centers.

         - Decontamination strategies  

    - Activated charcoal   3
    - Dermal/ocular decontamination   5
    - Enhanced elimination (awareness)   5
    - Gastric lavage (rare) awareness   3
    - Whole bowel irrigation (WBI) awareness   5
- Antidote principles and high-yield antidotes  

    - Antidote awareness set (board-level)   5
    - Fomepizole for toxic alcohols   4
    - N-acetylcysteine (NAC) for acetaminophen   5
    - Naloxone   4
    - Sodium bicarbonate for sodium-channel blockade   4
- Initial approach to the poisoned patient  

    - Consultation and disposition   5
    - History and exposure assessment   4
    - Key diagnostics   5
    - Stabilization (ABCDE) and glucose   5
    - Toxidrome recognition   5

###  Trauma And Injury 

   288 questions   

####  Orthopedic Injuries and Soft Tissue Trauma 

   103   

  Fractures, dislocations, compartment syndrome, wounds, and burns.

         - Burns and thermal injury  

    - Burn depth and TBSA estimation   4
    - Fluid resuscitation (conceptual)   4
    - Inhalation injury recognition   5
    - Initial burn management   4
    - Transfer to burn center criteria   4
- Compartment syndrome and crush injury  

    - Crush syndrome and rhabdomyolysis   5
    - Disposition   3
    - Fasciotomy timing and outcomes (conceptual)   4
    - Measurement and consultation   4
    - Recognition and exam pitfalls   4
- Dislocations and reduction complications  

    - Ankle and subtalar dislocation   5
    - Elbow and knee dislocations (high-risk)   4
    - Hip dislocation (time-critical)   3
    - Post-reduction care   4
    - Shoulder dislocation   5
- Fracture evaluation and immobilization principles  

    - Closed reduction indications (intro)   5
    - Disposition and follow-up   3
    - Imaging strategy   4
    - Neurovascular assessment   4
    - Open fractures   3
- Soft tissue injuries, bites, and infection risk  

    - Animal and human bites   5
    - Disposition and follow-up   4
    - Lacerations and tendon injuries   4
    - Necrotizing soft tissue infection red flags   4
    - Puncture wounds and foreign bodies   5

####  Safeguarding and Injury Prevention 

   65   

  Non-accidental trauma, interpersonal violence, and safeguarding responsibilities.

         - Elder abuse and neglect awareness  

    - Disposition   4
    - Medical evaluation   5
    - Pitfalls   4
    - Red flags   5
    - Reporting and safeguarding   3
- Intimate partner violence (IPV) and sexual violence (initial approach)  

    - Disposition and resources   4
    - Forensic considerations (awareness)   5
    - Mandatory reporting and legal interface (contextual)   3
    - Medical evaluation and treatment basics   5
    - Trauma-informed screening and response   4
- Non-accidental injury (NAI) and child abuse recognition  

    - Differential diagnosis pitfalls   4
    - Disposition   3
    - Mandatory reporting and safety planning   5
    - Red flags in history and exam   6
    - Workup and documentation   5

####  Trauma Systems and Initial Management 

   120   

  Assessment, imaging choices, stabilization priorities, and early trauma decision-making.

         - Abdominal and pelvic trauma  

    - Blunt abdominal trauma   6
    - Disposition   5
    - Genitourinary trauma awareness   5
    - Pelvic fracture and hemorrhage   4
    - Penetrating abdominal trauma (overview)   4
- Cervical spine and spinal cord injury  

    - Pain control and safe mobilization   4
    - Pitfalls   5
    - Spinal cord injury syndromes   5
    - Spinal immobilization and clearance   5
    - Thoracolumbar injury and cauda equina   5
- Thoracic trauma  

    - Imaging and disposition   4
    - Life-threatening chest injuries   4
    - Penetrating chest trauma   5
    - Pulmonary contusion and flail chest   5
    - Rib fractures and pain control   4
- Trauma primary survey and resuscitation priorities  

    - ABCDE with hemorrhage control   5
    - Analgesia, sedation, and hemodynamics   5
    - Disposition/transfer to trauma center   5
    - Mechanism of injury and occult injury risk   5
    - Trauma imaging strategy (conceptual)   5
- Traumatic brain injury (TBI) and head trauma  

    - Concussion and mild TBI   5
    - Disposition and observation   5
    - Intracranial hemorrhage patterns   6
    - Moderate/severe TBI stabilization   5
    - Skull and facial fractures   4

  Emergency Medicine Advanced Pathway

###  Clinical Decision Making 

   68 questions   

####  Advanced Diagnostic Reasoning and Risk Stratification 

   68   

  High-order decision-making, dynamic reassessment, and defensible disposition in complex and uncertai...

         - Disposition under uncertainty and safety-netting (advanced)  

    - End-of-life decisions in ED context   3
    - Managing “bounce-back” risk   2
    - Observation medicine design   3
    - Shared decision-making for discharge of borderline risk   3
    - Transfer decisions and risk balancing   2
- Dynamic differential diagnosis and reassessment  

    - Diagnostic time-outs and cognitive forcing strategies   3
    - Documentation of evolving reasoning   3
    - Managing conflicting data   3
    - Serial exams as a diagnostic tool   3
    - Trajectory-based reasoning   2
- Evidence-informed decision tools (advanced use and limitations)  

    - Balancing sensitivity with downstream harms   3
    - Bayesian framing at bedside   3
    - Defensible documentation   2
    - Integrating patient values   3
    - When decision rules apply vs do not apply   4
- High-risk complaint pathways (advanced application)  

    - Abdominal pain with diagnostic uncertainty   3
    - Chest pain with nondiagnostic testing   2
    - Dyspnea with mixed etiologies   2
    - Headache with negative initial imaging   2
    - Syncope risk and disposition (advanced)   3
- Managing multiple simultaneous patients and ED prioritization  

    - Documentation strategy in high-volume settings   3
    - Interruptions and task switching   3
    - Queue management and prioritization heuristics   2
    - Situational awareness in evolving events   3
    - Team utilization and delegation   3

###  Clinical Subspecialties 

   391 questions   

####  Communication and Collaboration 

   41   

  Advanced communication performance in conflict, uncertainty, and interprofessional teamwork.

         - Communicating uncertainty and shared decision-making (advanced)  

    - Challenging behaviors and de-escalation   3
    - Culturally safe and equitable communication   4
    - Discharge communication excellence   3
    - Informed refusal and capacity under stress   2
    - Risk communication techniques   3
- Delivering bad news and death notification  

    - After-death care and support   2
    - Conflict and blame prevention   2
    - Family presence and cultural considerations   4
    - Personal resilience and support   3
    - Structured approach and empathy   3
- Managing conflict with consultants and teams  

    - Documenting disagreements   2
    - Escalation frameworks   3
    - High-stakes handoffs   3
    - Negotiating shared plans   2
    - Team dynamics in resuscitation   2

####  Medical Toxicology (Advanced) 

   83   

  Complex overdose management, uncommon tox syndromes, and antidote escalation decisions.

         - Envenomation and exotic exposures  

    - Marine envenomation and toxin fish (awareness)   4
    - Plant and chemical exposures (awareness)   3
    - Public health and consultation   2
    - Snakebite management   3
    - Spider/scorpion and arthropod syndromes (awareness)   3
- Sports Medicine and Environmental/Undersea Medicine (Advanced)  

    - Altitude illness awareness   3
    - Concussion and return-to-play/return-to-learn   4
    - Diving and decompression illness awareness   2
    - Exertional heat illness in athletes   3
    - Hyperbaric indications and transfer coordination   2
- Complex mixed overdoses and tox consultation  

    - Advanced diagnostics and monitoring   3
    - Disposition planning   3
    - Documentation and poison center collaboration   2
    - Escalation therapies awareness   4
    - Pattern recognition in mixed toxidromes   3
- Neurocritical Care and Stroke Systems (Advanced)  

    - Intracerebral hemorrhage management details   2
    - Large vessel occlusion (LVO) identification and pathway   3
    - Refractory status epilepticus (advanced awareness)   2
    - Sedation and neuro exam balance   2
    - Subarachnoid hemorrhage and vasospasm awareness   3
- Pain Medicine and Substance Use Care (Advanced)  

    - Chronic pain, frequent visitors, and care plans   3
    - Complex pain and opioid-tolerant patients   3
    - Ethical prescribing and safety   2
    - Opioid use disorder (OUD) ED initiation pathways   2
    - Regional anesthesia expansion   2
- Pediatric Emergency Medicine (Advanced)  

    - Congenital heart disease emergencies (awareness)   3
    - Critically ill child approach   3
    - Pediatric respiratory failure and ventilation   3
    - Pediatric sepsis and meningitis   3
    - Pediatric trauma and safeguarding   3

####  Prehospital and Disaster 

   46   

  EMS medical direction, transfer medicine, and major incident management.

         - EMS medical direction and protocol oversight  

    - Documentation and medico-legal interface   3
    - Field triage and destination decisions   4
    - Online medical control communication   3
    - Protocol development principles   2
    - Safety and scene considerations   3
- Interfacility transfer and retrieval medicine  

    - Choosing transport modality and team   3
    - Special transfers   4
    - Stabilization before transfer   3
    - Transfer documentation and handoff   3
    - Transport risks and mitigation   2
- Mass casualty incidents (MCI) and disaster triage  

    - CBRN and hazmat response basics   3
    - Incident command principles   4
    - MCI triage systems awareness   3
    - Public health emergencies and outbreaks   3
    - Surge capacity and ED operations in disasters   3

####  Professionalism and Ethics 

   50   

  High-stakes professional practice: law interfaces, privacy, restraint, reporting, and ethical resour...

         - Ethics of resource scarcity and triage  

    - Bias mitigation in triage decisions   2
    - Communication with patients/families   2
    - Crisis standards of care awareness   2
    - ED boarding and competing priorities   2
    - MCI ethical dilemmas   2
- Privacy, confidentiality, and information sharing  

    - Digital documentation and imaging   3
    - ED confidentiality principles   3
    - Ethical pitfalls   3
    - Law enforcement interface   3
    - Mandatory disclosures (exceptions) awareness   3
- Capacity, consent, and refusal in complex cases  

    - Capacity in intoxication and delirium   3
    - Documentation for legal scrutiny   2
    - Minors and confidential care   2
    - Refusal of lifesaving care   3
    - Surrogate conflict and family disputes   2
- Restraint, agitation, and mental health law interfaces  

    - Disposition and continuity   2
    - Least-restrictive intervention framework   3
    - Legal holds and documentation (contextual)   2
    - Medical evaluation of agitation   3
    - Monitoring and complications   3

####  Scholarship and Education 

   58   

  Evidence-based practice, research literacy, teaching, assessment, and lifelong learning/CPD.

         - Scholarship, research methods, and ethics  

    - Academic professionalism   3
    - CPD and lifelong learning   4
    - Knowledge translation and dissemination   4
    - Protocol and project design basics   2
    - Research ethics and consent   3
- Guideline implementation and quality improvement (QI)  

    - Equity-focused QI   2
    - Patient safety event analysis   3
    - QI methods and measurement   2
    - Sustaining change   3
    - Translating guidelines into pathways   3
- Teaching and feedback in Emergency Medicine  

    - Assessment literacy (boards/orals/OSCE)   3
    - Bedside teaching models   3
    - Feedback and coaching skills   3
    - Procedural teaching and supervision   3
    - Simulation-based education   4
- Critical appraisal and clinical epidemiology (advanced)  

    - Applying evidence at bedside   2
    - Diagnostic studies and prediction rules   3
    - Interpreting RCTs and pragmatic trials   3
    - Observational studies and causal inference   2
    - Systematic reviews/meta-analysis interpretation   3

####  Special Populations (Advanced) 

   70   

  High-complexity scenarios in pregnancy, pediatrics, geriatrics, immunocompromised, and palliative ca...

         - Palliative care and end-of-life emergencies  

    - Communication skills   3
    - Disposition planning   2
    - Ethical dilemmas and conflict   2
    - Rapid goals-of-care conversations   3
    - Symptom control in ED   3
- Critically ill neonate/child (advanced)  

    - Complex safeguarding cases   3
    - Family communication under crisis   3
    - Neonatal resuscitation crossover essentials   2
    - Pediatric airway failure and RSI nuances   3
    - Pediatric shock and sepsis escalation   2
- Geriatric critical illness and anticoagulation complications  

    - Delirium and agitation in elderly (advanced)   3
    - DOAC/warfarin bleeding and reversal decisions   3
    - Elder abuse and neglect complex cases   3
    - End-of-life in older adults   3
    - Falls with occult injury and frailty   3
- High-risk pregnancy resuscitation and emergencies  

    - Disposition and medico-legal communication   4
    - Eclampsia and severe preeclampsia crisis   3
    - Obstetric hemorrhage initial management   3
    - Perimortem cesarean delivery awareness   2
    - Pregnancy airway and ventilation challenges   3
- Immunocompromised/oncology/transplant emergencies (advanced)  

    - Advanced hematologic emergencies   3
    - Disposition and infection control   3
    - Neutropenic sepsis escalation   3
    - Oncologic airway/SVC syndrome awareness   2
    - Transplant complications awareness   3

####  Systems Leadership 

   43   

  ED flow, governance, quality improvement, and leading multidisciplinary teams during routine and sur...

         - Leading teams and managing performance  

    - Conflict resolution and professionalism enforcement   2
    - Equity and inclusion leadership   3
    - Surge events leadership   3
    - Teaching and supervision in a busy ED   4
    - Team leadership behaviors   2
- Clinical governance and risk management  

    - Credentialing, supervision, and scope management   3
    - Guideline implementation and standardization   3
    - Incident review and root cause analysis (RCA) concepts   2
    - Managing complaints and adverse events   3
    - Medicolegal risk mitigation   3
- ED flow and crowding mitigation  

    - Communication during surge   3
    - Input-throughput-output framework   3
    - Metrics and performance dashboards (awareness)   3
    - Operational prioritization and resource allocation   3
    - Safety in crowding   3

###  Communication And Collaboration 

   13 questions   

####  Advanced Communication Skills 

   13   

  Category placeholder to maintain structure; see 'Communication and Collaboration' above for detailed...

         - Advanced communication comprehensive review  

    - Agitation and de-escalation communication   2
    - Bad news and death notification   2
    - Communicating uncertainty and shared decisions   3
    - Conflict and negotiation with teams/consultants   3
    - Equity-centered communication   3

###  Prehospital And Disaster 

   18 questions   

####  Prehospital Systems and Disaster Operations 

   18   

  Category placeholder to maintain structure; see 'Prehospital and Disaster' above for detailed topics...

         - Prehospital and disaster comprehensive review  

    - CBRN/hazmat/public health emergencies   4
    - EMS medical direction   3
    - Interfacility transfer/retrieval   3
    - MCI/disaster triage and command   4
    - Systems integration   4

###  Procedures And Ultrasound 

   145 questions   

####  Advanced Procedures Under Time Pressure 

   82   

  Procedural performance expected in oral/OSCE-style assessments, including complication handling.

         - Regional anesthesia and nerve blocks (ED)  

    - Complications   2
    - Documentation and aftercare   3
    - Indications and block selection   3
    - Local anesthetic dosing and LAST   3
    - Technique and ultrasound guidance awareness   2
- Advanced procedural sedation and analgesia  

    - Documentation and discharge criteria   2
    - Medication strategy by procedure   3
    - Monitoring and adverse event management   3
    - Risk stratification and airway planning   3
    - Special populations considerations   3
- Advanced vascular access and monitoring  

    - Arterial line placement (advanced awareness)   3
    - Central venous access with ultrasound   3
    - Intraosseous access troubleshooting   3
    - Medication infusion safety   3
    - Ultrasound-guided peripheral IV mastery   3
- Cricothyrotomy and rescue airway skills  

    - Complication management   3
    - Indications in failed airway   2
    - Post-procedure care   3
    - Team leadership during airway crisis   2
    - Technique performance   2
- Orthopedic procedures (advanced)  

    - Arthrocentesis and septic joint management   3
    - Compartment syndrome serial exams   3
    - Complex reductions and immobilization   3
    - Post-procedure care and disposition planning   3
    - Traction splinting and temporary stabilization   2
- Thoracic procedures (advanced)  

    - Complication recognition and rescue   3
    - Needle decompression technique optimization   2
    - Pericardiocentesis (awareness to performance)   2
    - Thoracentesis (diagnostic/therapeutic)   3
    - Tube thoracostomy and pigtail placement   4

####  Point-of-Care Ultrasound (Advanced Integration) 

   63   

  Acquisition, interpretation, and management integration of core POCUS applications and ultrasound-gu...

         - Early pregnancy and pelvic POCUS  

    - Documentation and QA   3
    - Ectopic suspicion signs   2
    - Gynecologic emergencies awareness   3
    - IUP identification and limitations   3
    - Pregnancy of unknown location (PUL) management integration   2
- Cardiac POCUS and shock integration (RUSH)  

    - Clinical integration and documentation   2
    - IVC and volume assessment limitations   3
    - LV/RV function gross assessment   2
    - Pericardial effusion/tamponade assessment   2
    - Views and image acquisition   2
- eFAST and abdominal vascular ultrasound  

    - AAA ultrasound   3
    - Biliary ultrasound   3
    - DVT ultrasound (compression)   3
    - eFAST performance and pitfalls   3
    - Hydronephrosis and renal ultrasound   2
- Lung ultrasound and respiratory failure  

    - Diaphragm and work of breathing awareness (low)   3
    - Documentation and workflow integration   2
    - Interstitial syndrome and pulmonary edema   3
    - Pleural effusion and consolidation   2
    - Pneumothorax detection   2
- Ultrasound-guided procedures  

    - Documentation and safety   3
    - Soft tissue ultrasound for abscess   3
    - US-guided nerve blocks awareness   2
    - US-guided thoracentesis/paracentesis awareness   3
    - US-guided vascular access   2

###  Professionalism And Ethics 

   37 questions   

####  Advanced Ethics in Complex Internal Medicine 

   23   

  Difficult cases, interprofessional tensions, and high-risk legal/ethical scenarios.

         - Ethics consultation triggers and frameworks  

    - Documentation and communication   4
    - Ethics in resource limitation   2
    - Identifying ethical dilemmas   2
    - Structured analysis   3
- Professionalism in difficult interactions  

    - Conflicts of interest in leadership roles   3
    - Equity and bias in professionalism   3
    - Interprofessional conflict resolution   3
    - Managing disruptive behavior   3

####  High-Stakes Professional Practice 

   14   

  Category placeholder to maintain structure; see 'Professionalism and Ethics' above for detailed topi...

         - Professionalism and ethics comprehensive review  

    - Capacity/consent/refusal complex cases   3
    - Confidentiality and law enforcement interface   3
    - Ethics of resource scarcity and triage   3
    - Professional documentation under scrutiny   2
    - Restraint and mental health law interfaces   3

###  Resuscitation And Critical Care 

   163 questions   

####  Advanced Airway Management 

   41   

  RSI optimization, difficult airway algorithms, and peri-intubation risk reduction.

         - Difficult airway prediction and planning  

    - Airway assessment frameworks   3
    - Airway plan A/B/C/D   3
    - Failed airway and rescue sequence   3
    - Peri-intubation hemodynamic optimization   3
    - Preoxygenation optimization   4
- Rapid sequence intubation (RSI) pharmacology and strategy  

    - Airway complications management   2
    - Induction agent selection   3
    - Neuromuscular blockade selection   2
    - Peri-intubation hypoxemia management   2
    - Post-intubation analgesia/sedation bundles   2
- Surgical airway (advanced performance)  

    - Complications and troubleshooting   3
    - Indications and timing   2
    - Pediatric considerations (awareness)   3
    - Team and CRM during CICO   3
    - Technique mastery (scalpel-bougie-tube)   3

####  Hemodynamics, Shock, and ED Critical Care 

   53   

  Advanced shock management, monitoring, vasopressor infusions, and ED-based critical care workflows.

         - Advanced shock differentiation and monitoring  

    - Dynamic fluid responsiveness concepts   3
    - ED-ICU workflow and reassessment cadence   2
    - Hemodynamic targets by shock type   2
    - Invasive monitoring awareness   3
    - RUSH/POCUS-guided shock evaluation   3
- Cardiac arrest and post-arrest critical care  

    - Advanced ACLS leadership   3
    - Neuroprognostication timing awareness   2
    - ROSC stabilization   3
    - Special arrest scenarios   3
    - Targeted temperature management (TTM) awareness   3
- Sepsis and septic shock (advanced)  

    - Antibiotic strategy under uncertainty   3
    - Early recognition in atypical patients   3
    - Fluids and de-resuscitation awareness   2
    - Sepsis documentation and quality measures pitfalls   2
    - Source control coordination   3
- Vasoactive infusions and pressor selection  

    - Adjuncts and second-line agents   3
    - First-line pressors by syndrome   3
    - Peripheral pressor administration safety   3
    - Refractory shock escalation   2
    - Titration and monitoring   2

####  Neurocritical emergencies 

   29   

  Advanced stabilization for elevated ICP, status epilepticus, and neurovascular catastrophes.

         - Elevated intracranial pressure and herniation syndromes  

    - Airway/ventilation strategy   2
    - Clinical recognition   4
    - Imaging and definitive management coordination   3
    - Immediate temporizing measures   3
    - Pitfalls   3
- Status epilepticus refractory management (advanced awareness)  

    - Airway and sedation strategy   2
    - Complication management   3
    - Disposition   3
    - Escalation beyond second-line agents   3
    - Identifying underlying cause quickly   3

####  Ventilation and Respiratory Failure Management 

   40   

  Mechanical ventilation/NIV strategies, ARDS principles, and ventilator troubleshooting.

         - Mechanical ventilation initial settings and physiology  

    - Lung-protective ventilation principles   2
    - PEEP titration and hemodynamics   2
    - Post-intubation care bundle   3
    - Ventilation in ARDS/pneumonia   2
    - Ventilation in obstructive disease   3
- Non-invasive ventilation (NIV) advanced application  

    - Contraindications and failure recognition   4
    - Escalation to intubation   3
    - Selecting CPAP vs BiPAP   3
    - Special scenarios   3
    - Titration and monitoring   2
- Ventilator troubleshooting and emergencies  

    - Approach to sudden deterioration on vent   3
    - Auto-PEEP and breath stacking   3
    - High pressure alarms   2
    - Low pressure alarms   3
    - Post-intubation hypotension and arrest prevention   2

###  Scholarship And Education 

   37 questions   

####  Advanced Educator and Scholar Competencies 

   22   

  Programmatic assessment, learning science, and scholarship dissemination.

         - Learning science and curriculum design (overview)  

    - Cognitive load and instructional design   2
    - Competency-based medical education (CBME)   3
    - Faculty development and coaching   3
    - Simulation-based education   3
- Scholarly writing and dissemination  

    - Academic career development   3
    - Educational scholarship   3
    - Presentation skills   3
    - Writing for publication   2

####  Scholarship, EBM, Teaching 

   15   

  Category placeholder to maintain structure; see 'Scholarship and Education' above for detailed topic...

         - Scholarship and education comprehensive review  

    - Assessment literacy for orals/OSCE   3
    - CPD and lifelong learning   3
    - Critical appraisal and EBM application   4
    - QI and guideline implementation   2
    - Teaching and feedback skills   3

###  Special Populations 

   396 questions   

####  Advanced Special Population Integration 

   14   

  Category placeholder to maintain structure; see 'Special Populations (Advanced)' domain set above.

         - Integrated advanced special populations review  

    - Critically ill neonate/child   3
    - Geriatric frailty and anticoagulation complications   3
    - High-risk pregnancy emergencies   3
    - Immunocompromised/oncology emergencies   3
    - Palliative and end-of-life care   2

####  Cultural, linguistic, and refugee mental health 

   17   

  Culturally safe care, interpreter use, trauma and displacement, and diagnostic adaptations.

         - Refugee trauma and complex needs  

    - Care coordination with social/legal supports   5
    - Pre-, peri-, post-migration stressors   4
- Cultural formulation and culturally bound expressions  

    - Eliciting explanatory models   5
    - Interpreter-mediated assessments   3

####  Geriatrics and Frailty (Core) 

   31   

  Atypical presentations, falls, delirium, polypharmacy, and disposition safety in older adults.

         - Atypical presentations and geriatric assessment  

    - Atypical infection/ACS presentations   3
    - Delirium recognition   3
    - Disposition safety   3
    - Frailty and functional assessment   4
    - Polypharmacy and adverse drug events   3
- Falls and trauma in older adults  

    - Disposition and safeguarding   3
    - Head injury on anticoagulants   3
    - Hip and pelvic fractures   4
    - Rib fractures and respiratory compromise   2
    - Syncope vs mechanical fall differentiation   3

####  High-Risk and Under-Served Groups (Advanced) 

   34   

  Clinical care tailored to specific physiologic and social contexts.

         - Care of patients with advanced cancer and comorbidities  

    - Complications of therapy affecting other organs   4
    - Decision-making under limited prognosis   2
    - Infection risk management   4
    - Transitions to hospice   3
- Patients with serious mental illness  

    - Capacity and adherence challenges   3
    - Delirium vs psychiatric symptom overlap   2
    - Metabolic monitoring for antipsychotics   2
    - Suicide risk in medical illness   3
- Patients with substance use disorders and complex illness  

    - Hospital-based addiction care   3
    - Infections related to injection drug use   3
    - Pain management with OUD   3
    - Trauma-informed care   2

####  Immunocompromised Patients (Core) 

   26   

  Oncology, transplant, HIV, and iatrogenic immunosuppression presentations and ED priorities.

         - Oncologic and therapy-related complications (intro)  

    - Disposition   2
    - Immunotherapy adverse events awareness   3
    - Spinal cord compression awareness   3
    - Thrombosis/PE risk in cancer   3
    - Tumor lysis syndrome awareness   2
- Fever in immunocompromised patients  

    - Disposition   2
    - HIV and opportunistic infection awareness   3
    - Neutropenic fever   2
    - Steroid/biologic immunosuppression   3
    - Transplant patient infection risk   3

####  Intellectual disability, autism, and communication differences 

   18   

  Adapting assessment and treatment for neurodevelopmental and cognitive differences across lifespan.

         - Challenging behavior and risk management  

    - Positive behavior support planning   4
    - Psychotropic use: target symptoms and monitoring   3
- Diagnostic overshadowing and medical contributors  

    - Communication-adapted interviewing   6
    - Pain, constipation, seizures, sleep problems   5

####  LGBTQ+ and gender-related mental health care 

   16   

  Affirming assessment, minority stress, gender dysphoria-related care principles, and psychiatric com...

         - Gender dysphoria care principles (within psychiatrist scope)  

    - Assessment and comorbidity evaluation   4
    - Collaborative care with gender-affirming services   5
- Minority stress and stigma-related mental health risks  

    - Assessment of discrimination, violence, and support   4
    - Suicide risk and protective interventions   3

####  Pediatrics 

   80   

  Age-specific assessment, stabilization, and high-risk pediatric presentations.

         - Febrile infant and pediatric sepsis (foundational)  

    - Disposition   4
    - Empiric antibiotics   5
    - Initial evaluation   4
    - Pitfalls   3
    - Risk stratification concepts by age   4
- Pediatric assessment and physiology essentials  

    - Age-adjusted vitals and shock recognition   4
    - Fever and serious bacterial infection risk   5
    - Pain assessment and analgesia   3
    - Pediatric airway differences   4
    - Safeguarding basics   5
- Pediatric dehydration and GI illness  

    - Assessment of dehydration   4
    - Disposition   3
    - Electrolyte derangements awareness   4
    - Oral rehydration therapy (ORT)   4
    - When to suspect surgical abdomen   5
- Pediatric respiratory distress syndromes  

    - Bronchiolitis   4
    - Croup   4
    - Disposition and family counseling   3
    - Foreign body aspiration   3
    - Pediatric asthma   5

####  Perinatal and reproductive psychiatry 

   16   

  Assessment and treatment planning around pregnancy, postpartum, lactation, and reproductive transiti...

         - PMDD and reproductive transitions  

    - Diagnosis and treatment overview   4
- Perinatal mood and anxiety disorders  

    - Medication risk-benefit counseling   4
    - Safety planning and mother-infant considerations   3
    - Screening and differential diagnosis   5

####  Pregnancy and Gynecologic Emergencies (Core) 

   86   

  Physiologic changes, early pregnancy complications, and common OB/GYN emergencies in the ED.

         - Second/third-trimester bleeding (overview)  

    - Disposition and transfer   4
    - Pitfalls   4
    - Placenta previa/abruption awareness   5
    - Postpartum hemorrhage awareness   5
    - Preterm labor awareness   6
- First-trimester bleeding and ectopic pregnancy  

    - Complications and pitfalls   5
    - Disposition   4
    - Initial evaluation   4
    - Management pathways   5
    - Ultrasound interpretation (conceptual)   4
- Hypertensive disorders of pregnancy (core)  

    - BP management principles   3
    - Disposition   3
    - HELLP syndrome awareness   3
    - Magnesium sulfate therapy   3
    - Preeclampsia/eclampsia recognition   5
- Pregnancy physiology and ED implications  

    - Cardiovascular/respiratory changes   5
    - Disposition and follow-up   4
    - Laboratory and imaging considerations   6
    - Resuscitation modifications   4
    - Trauma considerations   4

####  Safeguarding, Social Determinants, and Vulnerable Groups 

   42   

  Discharge planning and safety for patients with social vulnerability or safeguarding needs.

         - Homelessness, substance use, and high-utilization care  

    - Behavioral health comorbidity   4
    - Documentation and ethical considerations   2
    - Harm reduction in ED   2
    - Linkage to care and follow-up   3
    - Medical risks and barriers   3
- Patients with disabilities and communication barriers  

    - Capacity and consent considerations   2
    - Communication accommodations   2
    - Discharge planning   2
    - Pitfalls   3
    - Safeguarding and abuse risk   2
- Domestic violence and sexual assault (core)  

    - Forensic pathways awareness   3
    - Mandatory reporting (contextual)   3
    - Medical care essentials   4
    - Safety planning and resources   4
    - Trauma-informed care   3

####  Severe psychosocial vulnerability and marginalized contexts 

   16   

  Homelessness, incarceration, HIV, chronic pain, and other contexts requiring adapted and equitable c...

         - HIV and neuropsychiatric complications  

    - Depression, cognitive impairment, medication interactions   5
- Incarcerated individuals and reentry planning (overview)  

    - Continuity of care and medication access   3
- Chronic pain and opioid risk  

    - Integrated pain and mental health care   4
- Homelessness and serious mental illness  

    - Engagement and harm reduction   4

###  Systems Leadership 

   16 questions   

####  ED Leadership and Governance 

   16   

  Category placeholder to maintain structure; see 'Systems Leadership' above for detailed topics.

         - Systems leadership comprehensive review  

    - Clinical governance and risk management   4
    - ED flow and crowding   2
    - Metrics and quality balancing   3
    - Operations during disasters/surge   4
    - Team leadership and performance management   3

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