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3. Pediatrics

  Pediatrics curriculum 
=======================

 Conquer Pediatrics Boards with Calm, Clear Confidence

      Core   Advanced   

    Pediatrics Core Pathway

###  Acute And Emergency Care 

   247 questions   

####  Initial assessment, triage, and stabilization 

   66   

  Recognition of critical illness, ABCDE approach, resuscitation priorities, and safe disposition deci...

         - Airway management fundamentals  

    - Airway positioning and basic adjuncts   3
    - Bag-mask ventilation technique   4
    - Difficult airway and rescue strategies   3
    - Oxygen delivery methods   4
    - Rapid sequence intubation (RSI) overview   4
- Pediatric assessment triangle and triage frameworks  

    - ABCDE primary survey   4
    - Appearance, work of breathing, circulation to skin (PAT)   4
    - Disposition and escalation decisions   4
    - Secondary survey and history (SAMPLE/OPQRST)   4
    - Triage acuity and red flags   3
- Shock, dehydration, and sepsis  

    - Adrenal crisis recognition (safety-critical)   3
    - Anaphylaxis emergency management   3
    - Dehydration and gastroenteritis emergency management   3
    - Sepsis recognition and initial bundle concepts   3
    - Shock recognition and classification   3
- Vascular access and resuscitation procedures  

    - Blood product resuscitation (trauma and hemorrhage)   4
    - Fluid resuscitation principles   2
    - Intraosseous (IO) access   2
    - Peripheral IV and ultrasound-guided access (concept)   3
    - Point-of-care testing and bedside tools   3

####  Neurologic and toxicologic emergencies 

   61   

  Seizures, altered mental status, increased ICP, headaches, ingestions, and poisoning management prin...

         - Headache emergencies and increased intracranial pressure  

    - Idiopathic intracranial hypertension (IIH) overview   3
    - Intracranial hypertension initial management   4
    - Meningitis/encephalitis headache patterns   3
    - Migraine acute treatment basics   3
    - Red flags in pediatric headache   3
- Altered mental status (AMS) differential and approach  

    - Immediate reversible causes   3
    - Infection and CNS inflammation   3
    - Metabolic and endocrine causes   4
    - Toxicologic causes and toxidromes   4
    - Trauma and intracranial hemorrhage   3
- Poisoning and ingestion emergencies  

    - Button battery and magnet ingestion emergencies   3
    - Common high-risk ingestions   3
    - Household and environmental toxins   3
    - Initial stabilization and decontamination principles   2
    - Toxidrome-based management   3
- Seizure and status epilepticus management  

    - Acute benzodiazepine therapy   2
    - Febrile seizure approach   3
    - Immediate stabilization and glucose check   3
    - Nonconvulsive status and postictal states   3
    - Second-line anti-seizure medications (conceptual)   3

####  Respiratory emergencies and common ED presentations 

   60   

  Acute respiratory distress syndromes and high-frequency ED respiratory problems including asthma, br...

         - Acute asthma exacerbation management  

    - Discharge planning and controller initiation   3
    - Escalation therapies   4
    - First-line therapies   3
    - Severity assessment and monitoring   3
    - Ventilation risk and intubation pitfalls   3
- Bronchiolitis and infant respiratory distress  

    - Admission criteria and monitoring   2
    - Diagnosis and severity assessment   2
    - Differential diagnosis of wheezing infant   4
    - Supportive care and oxygen thresholds (conceptual)   3
    - Therapies generally not recommended (board framing)   3
- Croup and upper airway obstruction  

    - Airway emergencies differential   4
    - Assessment of severity and stridor   3
    - Corticosteroid therapy   2
    - Discharge vs admission criteria   2
    - Nebulized epinephrine use   3
- Pneumonia and severe respiratory infection in ED  

    - Antibiotic choices (community) concept   4
    - Clinical diagnosis and severity cues   3
    - Complications and escalation   3
    - Discharge instructions and follow-up   3
    - Viral vs bacterial differentiation limitations   3

####  Trauma, surgical, and procedural emergencies 

   60   

  Pediatric trauma principles, fractures, burns, abdominal emergencies, and procedural care including...

         - Burns and environmental injury  

    - Burn depth/extent estimation and initial care   3
    - Electrical injury and lightning   2
    - Fluid resuscitation in major burns (conceptual)   2
    - Heat illness and hypothermia   4
    - Inhalation injury recognition   3
- Common orthopedic emergencies  

    - Compartment syndrome and neurovascular emergencies   3
    - Fracture recognition and initial management   3
    - Limping child emergency differential   4
    - Septic arthritis vs transient synovitis   2
    - Supracondylar humerus fracture   2
- Pediatric procedural pain control and sedation (ED)  

    - Foreign body removal procedures   3
    - Laceration repair and wound care basics   3
    - Local anesthesia and nerve blocks (overview)   3
    - Pain assessment and multimodal analgesia   4
    - Procedural sedation safety   4
- Pediatric trauma primary survey and stabilization  

    - Abdominal trauma and FAST exam concept   3
    - Head trauma assessment and imaging decisions   4
    - Non-accidental trauma considerations   3
    - Shock in trauma and hemorrhage control   3
    - Spine precautions and airway considerations   2

###  Basic Sciences 

   2,168 questions   

####  Anatomy for anesthesia (airway, neuraxial, vascular, regional) 

   50   

         - Neuraxial anatomy and dermatomes  

    - Dermatome and block height assessment   4
    - Meninges and CSF spaces   4
    - Vertebral column and ligamentous structures   4
- Peripheral nerve anatomy (regional anesthesia essentials)  

    - Brachial plexus overview   5
    - Lower limb plexuses   5
    - Truncal blocks anatomy   5
- Upper airway anatomy and airway assessment landmarks  

    - Airway examination correlates   5
    - Nasal and oral cavity anatomy   4
    - Pharynx and larynx anatomy   5
- Vascular access anatomy  

    - Arterial access anatomy   4
    - Central venous anatomy   5

####  Anatomy, Surgical Anatomy &amp; Pelvic Support 

   70   

  Gross and applied anatomy relevant to obstetrics, gynecology, pelvic surgery, continence/prolapse, a...

         - Adnexa and tubo-ovarian anatomy  

    - Broad ligament spaces and adnexal torsion anatomy   2
    - Fallopian tube segments and function   3
    - Ovary—blood supply and surgical implications   2
    - Parametrium and ureteric course   2
    - Pelvic sidewall landmarks   3
- Bony pelvis, pelvic diameters, and obstetric biomechanics  

    - Anatomy relevant to operative vaginal birth   3
    - Maternal pelvis shapes and relevance   3
    - Mechanisms of labor and fetal head molding   3
    - Pelvic floor interaction with birth   3
    - Pelvimetry concepts and clinical utility   2
- Breast anatomy and lactation-relevant structures  

    - Breast ducts, lobules, and lymphatics   3
    - Breast imaging anatomy correlation   2
    - Nipple–areolar complex anatomy   3
    - Physiology-anatomy interface in lactation   3
    - Surgical anatomy (duct excision, abscess drainage) basics   3
- Pelvic floor, continence mechanisms and anorectal anatomy  

    - Anal sphincter complex   4
    - Levator ani and fascial supports   3
    - Lower urinary tract anatomy   2
    - Neurovascular anatomy relevant to pelvic pain   3
    - Perineum and episiotomy landmarks   3
- Uterus, cervix, vagina and vulva—applied anatomy  

    - Cervical anatomy and transformation zone   2
    - Lymphatic drainage of lower genital tract   3
    - Uterine layers and supporting ligaments   3
    - Vaginal anatomy and fornices   3
    - Vulvar anatomy   4

####  Applied Anatomy for Emergency Care 

   117   

  Regional anatomy relevant to resuscitation, procedures, and time-critical diagnosis.

         - Abdominal and pelvic anatomy for acute abdomen  

    - Appendix, bowel, mesentery   5
    - Genitourinary anatomy   5
    - Hepatobiliary and pancreatic anatomy   5
    - Pelvic anatomy and hemorrhage   3
    - Peritoneal spaces and referred pain   5
- Airway, neck, and upper aerodigestive anatomy  

    - Airway edema/obstruction implications   5
    - Larynx and trachea   4
    - Neck vascular/nerve structures   4
    - Surgical airway anatomy (foundational)   4
    - Upper airway landmarks   5
- Musculoskeletal compartments and vascular anatomy  

    - Compartment syndrome anatomy   4
    - Fracture patterns and growth plates (intro)   5
    - Major joints: stability and reduction basics   5
    - Ultrasound-relevant vascular anatomy   5
    - Vascular anatomy for hemorrhage control   5
- Neuroanatomy and spinal anatomy for EM  

    - Cerebral vascular territories (exam-relevant)   5
    - Intracranial compartments and herniation   4
    - Ocular and orbital anatomy   5
    - Peripheral nerve anatomy for injuries/blocks   5
    - Spinal cord/nerve root anatomy   5
- Thoracic anatomy and pleura  

    - Chest wall, ribs, diaphragm   5
    - Mediastinum and great vessels   6
    - Pericardium and cardiac anatomy basics   5
    - Pleural spaces and lung lobes   5
    - Procedural anatomy (thoracic)   3

####  Biochemistry, Metabolism &amp; Nutrition 

   37   

  Core metabolic pathways, organ metabolism, and clinically important deficiencies/excesses.

         - Carbohydrate and lipid metabolism (clinically applied)  

    - Glycolysis/gluconeogenesis concepts   3
    - Inborn errors (overview)   4
    - Lipid metabolism   3
    - Obesity and insulin resistance   2
- Micronutrients and deficiency syndromes  

    - Fat-soluble vitamins   3
    - Refeeding syndrome   3
    - Trace elements   3
    - Water-soluble vitamins   3
- Protein metabolism and liver synthetic function  

    - Albumin and oncotic pressure   4
    - Amino acid metabolism   4
    - Bilirubin metabolism   3
    - Coagulation factors synthesis   2

####  Cardiovascular physiology and measurement 

   71   

         - Cardiac electrophysiology and ECG basics  

    - Arrhythmia mechanisms (exam core)   5
    - Cardiac action potentials   4
    - Conduction system anatomy/physiology   5
    - Defibrillation/cardioversion principles   5
    - ECG interpretation for anesthesia   5
- Cardiac pump function and determinants of CO  

    - Autonomic control of circulation   5
    - Determinants of SVR and MAP   4
    - Frank–Starling physiology   5
    - Myocardial oxygen supply/demand   5
    - Pressure–volume concepts   6
    - Shock physiology (core principles)   5
- Oxygen transport and hemodynamic oxygenation metrics  

    - Hemoglobin–oxygen dissociation curve   4
    - Microcirculation basics   5
    - Oxygen consumption and extraction   4
    - Oxygen content and delivery   4

####  Cellular &amp; Molecular Biology 

   43   

  Core cellular structure/function and signaling relevant to disease mechanisms and therapeutics.

         - Cell structure, organelles, and trafficking  

    - Cell cycle, apoptosis, necrosis   3
    - Cell–cell junctions and extracellular matrix   4
    - Membrane structure &amp; transport   4
    - Organelles and key functions   4
- Oncogenesis fundamentals  

    - Cancer immunology (intro)   3
    - Carcinogenesis &amp; exposures   3
    - Hallmarks of cancer (board-level)   3
    - Tumor suppressors and oncogenes   4
- Signal transduction &amp; second messengers  

    - Inflammation signaling   4
    - Pharmacologic implications   3
    - Receptor classes   4
    - Second messengers   4

####  Clinical epidemiology, biostatistics, and evidence-based practice 

   55   

  Board-relevant study design, diagnostic testing performance, screening, clinical decision-making, an...

         - Basic statistics interpretation (board level)  

    - Confidence intervals   3
    - Hypothesis testing and p-values   3
    - Inter-rater reliability and kappa   2
    - Measures of central tendency and spread   3
    - Regression basics (conceptual)   3
- Diagnostic test characteristics  

    - Decision rules (e.g., PECARN concept)   3
    - Interpreting lab reference ranges in pediatrics   3
    - Likelihood ratios and post-test probability   2
    - ROC curves and thresholds (conceptual)   2
    - Sensitivity, specificity, predictive values   3
- Screening principles and prevention evidence  

    - Clinical practice guidelines (CPGs)   3
    - Criteria for screening programs   4
    - Ethics in evidence application   3
    - Number needed to treat/harm   3
    - Public health measures and outbreak basics   2
- Study designs and hierarchy of evidence  

    - Diagnostic test studies   3
    - Interventional studies (RCTs)   3
    - Observational studies (cohort, case-control, cross-sectional)   2
    - Quality improvement vs research (distinction)   3
    - Systematic reviews and meta-analyses   2

####  Clinical pharmacology and therapeutics (core) 

   76   

  Weight-based dosing, pediatric pharmacokinetics/dynamics, antimicrobial fundamentals, common drug cl...

         - Analgesia, sedation, and peri-procedural medications  

    - Common agents and adverse effects   4
    - Local anesthetics and toxicity   4
    - Non-opioid analgesics   3
    - Opioids and respiratory depression risk   3
    - Procedural sedation core concepts   4
- Antimicrobial classes and selection (foundational)  

    - Aminoglycosides and nephro/ototoxicity   2
    - Antiviral/antifungal overview (core)   3
    - Beta-lactams and cephalosporins   4
    - Macrolides and atypical coverage   3
    - MRSA agents (clindamycin, TMP-SMX, vancomycin, linezolid)   2
- Common pediatric chronic medication classes (core board level)  

    - Antiepileptic drugs overview   3
    - Asthma/allergy pharmacotherapy basics   4
    - Cardiac medications basics   3
    - Endocrine medications basics   3
    - Psychotropic basics (overview)   3
- Pediatric dosing principles and medication safety  

    - Adverse drug reaction types   3
    - Medication reconciliation and error prevention   3
    - Routes of administration and bioavailability   3
    - Therapeutic drug monitoring (TDM) basics   3
    - Weight-based dosing and dose limits   2
- Pediatric pharmacokinetics and pharmacodynamics  

    - Absorption differences by age   3
    - Distribution (body water/fat, protein binding)   3
    - Elimination (renal maturation)   3
    - Metabolism (hepatic enzymes)   2
    - Pharmacogenomics basics (board overview)   3

####  Core anesthesia pharmacology (drug classes) 

   95   

         - Cardiovascular drugs commonly used in anesthesia  

    - Antiarrhythmics (core familiarity)   4
    - Antihypertensives and antianginals   5
    - Vasopressors and inotropes   6
- Inhalational anesthetics  

    - MAC and factors affecting MAC   6
    - Organ effects and toxicity   6
    - Special phenomena   5
    - Uptake and distribution   4
- Intravenous induction agents and sedatives  

    - Benzodiazepines   4
    - Dexmedetomidine and alpha-2 agonists   4
    - Etomidate   4
    - Ketamine   5
    - Propofol   5
- Neuromuscular blockers and reversal agents  

    - Depolarizing blockade (succinylcholine)   4
    - Monitoring and reversal   4
    - NMJ physiology relevant to blockade   5
    - Nondepolarizing blockade   4
- Opioids and adjunct analgesics  

    - Adjuvant analgesics (exam-relevant)   4
    - Common IV opioids in anesthesia   5
    - Non-opioid analgesics (core)   5
    - Opioid receptor pharmacology   6

####  Core Physiology and Pathophysiology 

   147   

  High-yield physiologic principles that underpin ED presentation patterns and first-line therapy.

         - Acid–base physiology and interpretation  

    - Metabolic acidosis   4
    - Metabolic alkalosis   5
    - Osmolar gap and toxin clues   4
    - Respiratory acidosis/alkalosis   5
    - Systematic interpretation approach   5
- Inflammation, immunity, and sepsis pathobiology  

    - Anaphylaxis physiology   5
    - Coagulation-inflammation interface   5
    - Fever physiology   4
    - Host response to infection   6
    - Vaccines, immunization status, and ED relevance   5
- Neurophysiology of consciousness, seizure, and delirium  

    - Delirium and encephalopathy mechanisms   3
    - Raised ICP physiology   4
    - Reticular activating system and coma basics   6
    - Seizure generation and termination (conceptual)   4
    - Temperature and CNS function   5
- Oxygen delivery, shock physiology, and perfusion  

    - Determinants of oxygen delivery   4
    - Fluid responsiveness and endpoints   5
    - Reperfusion and resuscitation complications   5
    - Shock classification and physiology   6
    - Vasopressors/inotropes physiology   6
- Renal physiology and electrolyte homeostasis  

    - Acute kidney injury pathophysiology   6
    - Calcium, magnesium, phosphate physiology   6
    - Diuretics and renal pharmacodynamics (intro)   5
    - Potassium physiology and membrane excitability   6
    - Sodium and water balance   5
- Respiratory mechanics and gas exchange  

    - Acid-base interplay in respiratory disease   4
    - Hypoxemia mechanisms   5
    - Ventilation strategy principles (intro)   5
    - Ventilation vs oxygenation concepts   5
    - Work of breathing and fatigue   4

####  Developmental physiology and anatomy 

   103   

  Age-dependent structure and function across fetal, neonatal, infant, child, and adolescent stages re...

         - GI, hepatic, and pancreatic developmental physiology  

    - Bilirubin metabolism   2
    - Feeding physiology and gastric emptying   4
    - Gut microbiome concepts (board-relevant)   3
    - Liver synthetic function and vitamin K   3
    - Pancreatic function maturation   2
- Neurodevelopmental physiology (foundation)  

    - Brain development timing and vulnerability   3
    - Intracranial pressure basics   3
    - Pain pathways and developmental differences   3
    - Seizure physiology overview   3
    - Sleep physiology across development   3
- Fetal-to-neonatal transition physiology  

    - Cardiovascular transition and shunts   3
    - Neonatal glucose homeostasis   3
    - Placental to pulmonary gas exchange transition   3
    - Respiratory adaptation   3
    - Thermoregulation at birth   3
- Hematopoiesis and pediatric hemostasis basics  

    - Age-based CBC norms   3
    - Coagulation and bleeding evaluation foundations   3
    - Hemoglobin switching and oxygen affinity   3
    - Iron metabolism and erythropoiesis   3
    - Transfusion medicine basics   4
- Pediatric cardiovascular physiology basics  

    - Blood pressure norms and perfusion   3
    - Cardiac output determinants by age   2
    - Congenital heart physiology patterns   3
    - Oxygen delivery and consumption   2
    - Shock physiology overview   3
- Pediatric respiratory mechanics basics  

    - Age-dependent airway anatomy   3
    - Basic blood gas interpretation   4
    - Pulmonary defense mechanisms   3
    - Ventilation-perfusion relationships   3
    - Work of breathing and fatigue   2
- Renal maturation and fluid homeostasis  

    - Acid handling and bicarbonate physiology   3
    - Neonatal electrolyte vulnerabilities   3
    - Neonatal renal function and GFR maturation   3
    - Urine output norms and interpretation   3
    - Water balance regulation   3

####  Embryology, Fetal Development &amp; Congenital Anomalies 

   42   

  Embryology and developmental physiology underpinning congenital anomalies and reproductive tract dis...

         - Gametogenesis, fertilization, implantation and early placentation  

    - Amniotic fluid development and regulation   3
    - Fertilization and early embryo development   2
    - Implantation physiology and abnormal implantation   3
    - Oogenesis and spermatogenesis essentials   3
    - Placental development and cord formation   3
- Müllerian development and reproductive tract anomalies  

    - Cervical insufficiency developmental considerations   2
    - Congenital anomalies—screening principles   3
    - Müllerian duct fusion and canalization   3
    - Ovarian and testicular differentiation   3
    - Urogenital sinus development   2
- Organogenesis and teratology timing  

    - Common teratogens and patterns   5
    - Congenital infection pathogenesis (TORCH concept)   3
    - Critical periods of development   2
    - Fetal growth regulation   2
    - Placental transfer and fetal drug exposure   3

####  Emergency Pharmacology and Therapeutics 

   117   

  PK/PD and emergency drug classes frequently tested and used in ED resuscitation and symptom control.

         - Analgesia in emergency medicine  

    - Ketamine for analgesia   3
    - Non-opioid analgesics   5
    - Opioid pharmacology and safe prescribing   6
    - Pain syndromes and multimodal strategy   4
    - Regional anesthesia principles (intro)   5
- Antimicrobials and stewardship essentials  

    - Allergy, anaphylaxis, and cross-reactivity   5
    - Antibiotic adverse effects   5
    - Antiviral/antifungal (board-level)   5
    - Empiric antibiotic selection principles   4
    - High-yield ED syndromes (empiric)   4
- Cardiovascular and vasoactive medications  

    - Antiarrhythmics and rate control   5
    - Antihypertensives in emergencies   5
    - Antithrombotics and reperfusion adjuncts   6
    - Reversal agents (core overview)   5
    - Vasopressors/inotropes   5
- Pharmacokinetics/pharmacodynamics in the ED  

    - Absorption, distribution, metabolism, elimination   4
    - Drug interactions and adverse drug events   5
    - Medication safety principles   5
    - Onset/offset and context-sensitive half-time   5
    - Pharmacogenomics and variability (board-level)   3
- Sedation, induction agents, and anxiolysis  

    - Benzodiazepines   5
    - Dexmedetomidine (board-level overview)   4
    - Ketamine dissociation   4
    - Procedural sedation safety   5
    - Propofol and etomidate basics   5

####  Epidemiology, Biostatistics &amp; Evidence-Based Medicine 

   45   

  Study design, bias, test performance, causality, and applying evidence to patient care.

         - Clinical guidelines and evidence synthesis  

    - Ethics in research   3
    - GRADE and strength of recommendation   3
    - Implementation and de-implementation   3
    - Systematic reviews/meta-analyses   3
- Diagnostic test interpretation  

    - Bayesian reasoning   2
    - Core measures   3
    - ROC curves and thresholds   2
    - Screening principles   3
- Study design and validity  

    - Bias and confounding   3
    - Causality and inference   3
    - Interventional trials   3
    - Observational designs   4
- Treatment effects and risk  

    - Decision analysis basics   3
    - Effect size measures   2
    - Heterogeneity and subgroup analyses   3
    - Time-to-event analysis   2

####  Fluids, electrolytes, and acid–base 

   83   

  Core calculations and physiologic reasoning for pediatric fluid management, electrolyte abnormalitie...

         - Calcium, magnesium, and phosphate disorders  

    - Hypercalcemia differential and initial workup   2
    - Hypomagnesemia and refractory hypokalemia/hypocalcemia   2
    - Neonatal hypocalcemia (early/late)   3
    - Phosphate abnormalities (refeeding, DKA)   3
    - QT prolongation and electrolyte-related arrhythmias   3
- Acid–base disorders and interpretation  

    - Bicarbonate therapy: indications and risks   4
    - Metabolic acidosis differential (high vs normal anion gap)   4
    - Metabolic alkalosis differential   3
    - Respiratory acidosis/alkalosis scenarios   3
    - Stepwise blood gas interpretation   3
- Hypernatremia in children  

    - Central diabetes insipidus management   3
    - Correction strategy and monitoring   3
    - Etiologies and diagnostic approach   3
    - Nephrogenic diabetes insipidus basics   2
    - Neurologic complications of dysnatremias   2
- Hyponatremia in children  

    - Acute symptomatic hyponatremia management   3
    - Classification by volume status   3
    - Osmotic demyelination risk   2
    - Pseudohyponatremia and lab pitfalls   3
    - SIADH approach   3
- Maintenance fluids and dehydration management  

    - Assessment of dehydration severity   3
    - Hypernatremic dehydration   2
    - IV fluid bolus and deficit replacement   3
    - Maintenance fluid calculation and composition   3
    - Oral rehydration therapy (ORT)   2
- Potassium disorders (hypo/hyperkalemia)  

    - Hyperkalemia emergency management   3
    - Hyperkalemia recognition and ECG changes   3
    - Hypokalemia causes and evaluation   2
    - Renal tubular disorders related to potassium   3
    - Replacement strategies and safety   2

####  Genetics &amp; Genomics 

   31   

  Mendelian and complex genetics, genomic medicine, and clinically actionable variants.

         - Complex traits and gene–environment interaction  

    - Epigenetics   3
    - Microbiome (board-level concepts)   2
    - Polygenic risk concepts   3
    - Somatic mosaicism &amp; clonal hematopoiesis   2
- Genomic testing in clinical practice  

    - Ethical issues   2
    - Pharmacogenomics   3
    - Testing modalities   2
    - Variant interpretation   3
- Mendelian inheritance and risk  

    - Autosomal dominant patterns   3
    - Autosomal recessive patterns   3
    - Mitochondrial inheritance   2
    - X-linked inheritance   3

####  Genetics and metabolism (introductory) 

   57   

  Foundations of inheritance, genetic testing, dysmorphology approach, and introductory inborn error r...

         - Dysmorphology and congenital anomaly approach  

    - Approach to a dysmorphic child   3
    - Common genetic syndromes (core list)   3
    - Referral and multidisciplinary care   2
    - Syndromic vs sequence vs association concepts   3
    - Teratology basics   4
- Inborn errors: pattern recognition (intro)  

    - Hypoglycemia patterns and ketones   3
    - Lactic acidosis and mitochondrial disease overview   2
    - Metabolic acidosis and hyperammonemia patterns   3
    - Newborn with lethargy/vomiting after feeds   3
    - Recurrent rhabdomyolysis and exercise intolerance   2
- Genetic testing modalities and indications  

    - Ethical considerations in pediatric genetics   2
    - Karyotype, microarray, and targeted panels   3
    - Newborn screening follow-up basics   3
    - Prenatal testing concepts (board-level)   2
    - Single-gene sequencing and exome/genome sequencing   3
- Patterns of inheritance and pedigree interpretation  

    - Autosomal dominant/recessive patterns   3
    - Chromosomal abnormalities overview   4
    - De novo variants and recurrence risk   3
    - Multifactorial inheritance and risk   3
    - X-linked and mitochondrial inheritance   3

####  Genetics, Immunology, Hematology &amp; Teratology 

   65   

  Genetic principles, prenatal screening/diagnosis frameworks, immunohematology (Rh), and teratology r...

         - Genetic inheritance and counseling fundamentals  

    - Carrier screening concepts   4
    - Chromosomal abnormalities and mechanisms   4
    - Consanguinity and risk quantification basics   2
    - Genetic test ethics and informed consent   3
    - Patterns of inheritance   4
- Immunohematology and alloimmunization  

    - Fetal anemia assessment principles   2
    - Non-D antibodies and clinical relevance   3
    - RhD immunization prevention   3
    - Thrombophilia concepts   3
    - Transfusion medicine basics in OB   4
- Prenatal screening and diagnostic testing  

    - Aneuploidy screening modalities   3
    - Diagnostic procedures principles   3
    - Neural tube defect screening and diagnosis   4
    - Non-immune hydrops framework   3
    - Screening test performance interpretation   3
- Teratology and environmental exposures  

    - Infections as teratogens (TORCH)   4
    - Medication risk frameworks   3
    - Occupational/environmental hazards   4
    - Radiation exposure in pregnancy   3
    - Substance use and fetal effects   3

####  Hematology, Transfusion, and Evidence-Based Medicine 

   94   

  Coagulation, transfusion science, and biostatistics/EBM essentials commonly assessed in EM training...

         - EBM in practice: guidelines, pathways, and stewardship  

    - Antimicrobial and imaging stewardship   4
    - Applying guidelines safely   3
    - Critical incident literature appraisal (M&amp;M style)   4
    - Quality metrics vs patient-centered outcomes   4
    - Screening and prevention in ED context   5
- Biostatistics and clinical epidemiology for EM  

    - Bias, confounding, and validity   4
    - Clinical prediction rules and implementation   6
    - Diagnostic test performance   5
    - Measures of effect and uncertainty   4
    - Study designs and hierarchy of evidence   5
- Hemostasis and coagulation fundamentals  

    - Bleeding risk stratification (conceptual)   4
    - Coagulopathies in the ED   6
    - Heparin/DOAC physiology and lab interpretation   5
    - Primary vs secondary hemostasis   6
    - Thrombosis physiology   5
- Transfusion medicine and massive hemorrhage basics  

    - Blood products and indications   5
    - Hemolysis and anemia emergencies   5
    - Massive transfusion principles   5
    - Rh/alloimmunization principles (ED-relevant)   4
    - Transfusion reactions   5

####  Immunology &amp; Inflammation 

   36   

  Innate/adaptive immunity, hypersensitivity, autoimmunity, immunodeficiency, and transplant fundament...

         - Adaptive immunity  

    - B cell biology and antibodies   4
    - Hypersensitivity reactions   3
    - T cell biology   3
    - Vaccinology principles   2
- Autoimmunity and tolerance  

    - Central and peripheral tolerance   3
    - Immunodeficiency overview   3
    - Systemic autoimmune disease mechanisms   3
    - Transplant immunology (intro)   3
- Innate immunity and inflammation  

    - Complement system   3
    - Inflammation resolution   3
    - Pattern recognition and cytokines   3
    - Phagocytes and granulomatous inflammation   3

####  Immunology, inflammation, and allergy foundations 

   84   

  Fundamental immune mechanisms, hypersensitivity, primary immunodeficiency red flags, and vaccine imm...

         - Autoimmunity and immune dysregulation fundamentals  

    - Autoantibodies and immune tolerance concepts   3
    - Autoinflammatory syndromes (intro)   4
    - Cytokine storm/HLH conceptual bridge   3
    - Cytopenias and autoimmune disease links   3
    - Immune-mediated kidney and skin disease examples   3
- Hypersensitivity and allergic disease mechanisms  

    - Atopic disease spectrum   4
    - Drug allergy vs intolerance   3
    - Food allergy mechanisms and tolerance   4
    - Type I (IgE-mediated) reactions   4
    - Type II/III/IV hypersensitivity examples   4
- Innate and adaptive immune system basics  

    - Adaptive immunity components   4
    - Complement system basics   3
    - Inflammation resolution and chronic inflammation   3
    - Innate immunity components   4
    - Mucosal immunity and IgA   3
- Primary immunodeficiency (PID) overview and red flags  

    - Basic lab evaluation of immune function   3
    - Clinical warning signs and patterns   3
    - Immunization considerations in immunocompromise   3
    - Secondary immunodeficiency causes   3
    - T-cell vs B-cell vs phagocyte vs complement defects   4
- Vaccine immunology foundations  

    - Active vs passive immunity principles   3
    - Adjuvants and immunogenicity   3
    - Herd immunity and population impact (exam framing)   4
    - Live attenuated vs inactivated vaccines   3
    - Vaccine adverse events and safety systems   3

####  Maternal–Fetal Physiology, Placenta &amp; Parturition 

   55   

  Pregnancy adaptations, uteroplacental unit physiology, and labor physiology essential for safe obste...

         - Maternal cardiovascular and hemodynamic adaptations  

    - Blood pressure physiology across trimesters   3
    - Changes in blood volume, CO, SVR   3
    - Coagulation physiology (hypercoagulability)   2
    - Postpartum hemodynamic shifts   3
    - Uterine blood flow physiology   2
- Placental function, transport, and endocrine activity  

    - Amniotic fluid dynamics   3
    - Maternal–fetal immunology   2
    - Placental endocrine hormones   3
    - Placental transport mechanisms   3
    - Umbilical and fetal circulation physiology   3
- Respiratory, renal, and acid–base physiology in pregnancy  

    - GI/hepatic adaptations   3
    - Hematologic adaptations beyond coagulation   3
    - Renal changes and lab interpretation   3
    - Thermoregulation and skin changes   3
    - Ventilatory changes and ABG interpretation   2
- Uterine contractility and cervical remodeling  

    - Cervical ripening mechanisms   3
    - Lactation physiology   3
    - Myometrial excitation–contraction coupling   2
    - Postpartum uterine involution   2
    - Stages of labor physiology   4

####  Neurophysiology, autonomics, and thermoregulation 

   43   

         - Autonomic nervous system and reflexes  

    - Autonomic failure and dysautonomia   6
    - Key perioperative reflexes   5
    - Sympathetic vs parasympathetic physiology   5
- Cerebral blood flow and intracranial dynamics  

    - CBF regulation   5
    - CSF production and drainage   4
    - ICP physiology   4
- Thermoregulation and perioperative hypothermia  

    - Anesthesia effects on temperature   5
    - Complications of hypothermia   4
    - Normal thermoregulatory control   5

####  Nutrition, growth biology, and metabolic fundamentals 

   76   

  Core pediatric nutrition and metabolism including breastfeeding, micronutrients, malnutrition, obesi...

         - Energy metabolism and common IEM overview (intro)  

    - Acute metabolic decompensation first steps   2
    - Basic pathways (glycogen, FAO, urea cycle)   4
    - Hypoglycemia differential by age   3
    - Newborn screen concept and limitations   2
    - When to refer for metabolic/genetic evaluation   3
- Failure to thrive (FTT) and malnutrition  

    - Definitions and anthropometric assessment   3
    - Differential diagnosis framework   3
    - Initial evaluation and targeted testing   3
    - Multidisciplinary management and safeguarding interface   3
    - Nutritional rehabilitation   3
- Infant feeding (breastfeeding and formula)  

    - Breast milk composition and benefits (exam framing)   2
    - Complementary feeding and allergen introduction   4
    - Feeding difficulties and red flags   3
    - Formula types and indications   4
    - Lactation management basics   3
- Micronutrients and deficiency states  

    - Iodine and thyroid development   3
    - Iron deficiency and anemia prevention   2
    - Vitamin A, E, K deficiencies (board-relevant)   4
    - Vitamin D and calcium   4
    - Zinc and trace elements   3
- Pediatric obesity and metabolic risk  

    - BMI classification and staging   4
    - Lifestyle intervention fundamentals   2
    - Metabolic syndrome and NAFLD overview   3
    - Obesity pharmacotherapy and bariatric basics (board overview)   3
    - Weight stigma and counseling skills   3

####  Pathology &amp; General Pathophysiology 

   35   

  General injury, repair, vascular pathology, thrombosis, and systemic responses to illness.

         - Cell injury and adaptation  

    - Amyloidosis (overview)   3
    - Edema and effusions pathophysiology   3
    - Inflammation and repair   3
    - Reversible vs irreversible injury   3
- Fever, SIRS, and sepsis biology  

    - Biomarkers (concepts)   3
    - Cytokine-mediated shock   3
    - Organ dysfunction mechanisms   3
    - Stress response and endocrine changes   3
- Hemostasis and thrombosis (mechanisms)  

    - Atherosclerosis &amp; aneurysm pathophysiology   3
    - Coagulation cascade (clinical interpretation)   3
    - Platelet biology   2
    - Thrombosis and embolism   3

####  Pathology, Neoplasia, and Breast Pathology Foundations 

   73   

  Core gynecologic and obstetric pathology and tumor biology underpinning screening, diagnosis, and in...

         - Inflammation, infection, and tissue response basics  

    - Acute vs chronic inflammation patterns   2
    - Necrosis patterns relevant to OB-GYN   3
    - Pathology specimen handling basics   3
    - Thrombosis and embolism concepts   3
    - Wound healing and scar formation   3
- Breast pathology foundations for OB-GYN  

    - Benign breast disease   3
    - Breast cancer basics for generalists   3
    - Breast screening and pathology correlation   4
    - High-risk lesions overview   3
    - Lactation-related breast conditions   3
- Cervical pathology and HPV-mediated disease  

    - CIN/HSIL/LSIL pathologic correlates   3
    - Cytology and histology interpretation basics   3
    - HPV biology and carcinogenesis   3
    - Invasive cervical cancer—histology overview   3
    - Vaginal/vulvar intraepithelial lesions basics   3
- Endometrial pathology and AUB foundations  

    - Benign uterine pathology   3
    - Endometrial carcinoma basics (Type 1 vs Type 2)   3
    - Endometrial hyperplasia classification concepts   2
    - Gestational endometrium and retained products concepts   3
    - Uterine sarcomas overview   3
- Ovarian, tubal, and peritoneal tumors—foundations  

    - Borderline tumors concepts   2
    - Fallopian tube origin hypothesis for HGSC   3
    - GTD pathology overview   3
    - Ovarian tumor classification overview   3
    - Tumor markers basics   3

####  Pharmacology fundamentals (PK/PD and drug handling) 

   61   

         - Pharmacodynamics and receptor theory  

    - Dose–response relationships   4
    - Drug interactions   5
    - Pharmacogenomics (core testables)   5
    - Receptor types and signaling   5
- Pharmacokinetics core concepts  

    - Bioavailability and first-pass metabolism   5
    - Compartment models and parameters   6
    - Organ failure effects on PK   5
    - Redistribution and tissue uptake   4
    - Special populations   5
- Toxicology and adverse drug reactions  

    - Dose-related vs idiosyncratic reactions   4
    - Local anesthetic systemic toxicity (principles)   5
    - Methemoglobinemia and CO toxicity (periop)   4
    - Opioid toxicity and reversal   4

####  Pharmacology, Microbiology &amp; Diagnostic Science (Core) 

   83   

  High-yield medication classes, antimicrobial principles, vaccination and infection concepts, plus di...

         - Diagnostic test interpretation and screening science  

    - Bias and confounding in diagnostic studies   3
    - Critical values and escalation thresholds   3
    - Reference ranges and pregnancy-adjusted labs   3
    - Screening program principles   3
    - Test characteristics and Bayes theorem intuition   3
- Gynecologic pharmacology and contraception hormones  

    - Antibiotics/antifungals commonly used in GYN   4
    - Combined hormonal contraception (CHC) pharmacology   3
    - Emergency contraception   2
    - Menopause therapies   3
    - Progestin-only methods   4
- Medication safety in pregnancy and lactation  

    - Medication safety in breastfeeding   3
    - Peripartum anesthesia/analgesia pharmacology basics   4
    - Pharmacovigilance and counseling resources   4
    - Principles of prescribing in pregnancy   3
    - Teratogenic medication classes (core list)   4
- Microbiology, immunology and infection prevention  

    - Immunization principles for OB-GYN   3
    - Postoperative and postpartum infections   5
    - Pregnancy infections   3
    - STI microbiology essentials   3
    - Vaginal microbiome and common vaginitis   4
- Obstetric medication classes  

    - Diabetes medications in pregnancy   3
    - Hypertension medications in pregnancy   3
    - Thromboprophylaxis and anticoagulants   3
    - Tocolytics and preterm birth meds   4
    - Uterotonics and postpartum hemorrhage meds   3

####  Physics, measurement, mathematics, statistics (foundations) 

   56   

         - Radiation, MRI, and ultrasound physics (foundations)  

    - Ionizing radiation basics   3
    - MRI environment hazards   4
    - Ultrasound fundamentals   4
- Electrical safety and basic electronics  

    - Electrical hazards in OR   5
    - Ohm’s law and power   5
- Flow, pressure, and resistance  

    - Laminar vs turbulent flow   5
    - Poiseuille and Bernoulli principles   5
- Gas laws and vapors relevant to anesthesia  

    - Core gas laws   5
    - Humidity and airway gas conditioning   5
    - Vaporization concepts   5
- Mathematics, dosing, and basic statistics  

    - Data interpretation basics   5
    - Unit conversions and drug calculations   5

####  Physiology &amp; Homeostasis 

   50   

  System physiology emphasizing integration and mechanisms behind common clinical syndromes.

         - Cardiovascular physiology  

    - ECG electrophysiology basics   4
    - Exercise physiology   3
    - Hemodynamics and cardiac output   3
    - Vascular biology   3
- Endocrine physiology  

    - Calcium and bone metabolism   4
    - Glucose homeostasis   4
    - Hypothalamic–pituitary axes   3
    - Thyroid hormone action   3
- Renal physiology &amp; volume regulation  

    - Acid–base renal handling   3
    - Glomerular filtration and hemodynamics   3
    - Tubular handling of electrolytes   3
    - Water balance   3
- Respiratory physiology  

    - Acid–base and respiratory compensation   3
    - Hypoxic pulmonary vasoconstriction   2
    - Lung mechanics   3
    - Ventilation/perfusion and gas exchange   3

####  Reproductive Endocrinology &amp; Menstrual Cycle Physiology 

   45   

  Hormonal regulation across lifespan: puberty, cycle, pregnancy, lactation, menopause; core board phy...

         - Hypothalamic–pituitary–ovarian (HPO) axis regulation  

    - Endometrial cycle and histology   3
    - FSH/LH actions and ovarian steroidogenesis   3
    - GnRH pulsatility and feedback loops   4
    - Ovulation physiology and luteal phase   3
    - Puberty physiology and normal variants   3
- Menopause and perimenopause physiology  

    - Cardiometabolic changes around menopause   3
    - Hormone therapy physiologic rationale and risks   4
    - Ovarian aging and follicular depletion   3
    - Premature ovarian insufficiency (POI) physiology   2
    - Urogenital atrophy (GSM) pathophysiology   3
- Pregnancy endocrine physiology  

    - Calcium/vitamin D and bone metabolism   3
    - hCG, corpus luteum rescue, and placental takeover   2
    - Insulin resistance and metabolic adaptations   3
    - Postpartum endocrine changes   3
    - Thyroid physiology in pregnancy   3

####  Respiratory physiology and acid–base 

   73   

         - Acid–base and electrolytes (physiology foundations)  

    - Anion gap and lactate interpretation   4
    - Henderson–Hasselbalch and bicarbonate buffering   5
    - Key electrolytes for anesthesia   5
    - Stewart/strong ion approach (conceptual)   5
- Control of breathing and perioperative respiratory depression  

    - Central and peripheral chemoreceptors   5
    - Neuromuscular weakness and ventilation   4
    - Ventilatory responses to anesthesia and opioids   4
- Gas exchange: diffusion, V/Q, shunt  

    - Alveolar gas equation and A–a gradient   5
    - CO2 transport and elimination   5
    - Hypoxic pulmonary vasoconstriction (HPV)   4
    - V/Q mismatch vs shunt vs diffusion limitation   5
- Lung volumes, compliance, resistance, and work of breathing  

    - Airway resistance and flow   4
    - Closing capacity and FRC   4
    - PFT patterns for anesthesia   5
    - Static and dynamic compliance   6
    - Ventilation distribution and time constants   3

###  Behavioral And Psychosocial Health 

   132 questions   

####  Common pediatric behavioral and mental health disorders 

   75   

  Core outpatient behavioral health presentations: ADHD, anxiety, depression, ASD, behavior problems,...

         - ADHD evaluation and management  

    - Behavioral interventions and school supports   3
    - Comorbidity screening   3
    - Diagnostic criteria and differential   3
    - Medication management (stimulants and non-stimulants)   3
    - Monitoring and follow-up   4
- Anxiety disorders in children and adolescents  

    - Common anxiety presentations by age   2
    - First-line treatments   4
    - Panic attacks and acute anxiety management   3
    - Screening and assessment   3
    - SSRI use basics and safety   4
- Autism spectrum disorder (ASD) and neurodiversity-affirming care  

    - Behavioral supports and therapies (overview)   3
    - Common comorbidities   3
    - Core features and early signs   4
    - Counseling families and resources   3
    - Screening and referral pathways   2
- Behavior problems, ODD/conduct concerns, and aggression  

    - Behavioral interventions and parent management training   3
    - Crisis management and safety   2
    - Medication role (overview)   3
    - Normal vs concerning behavior by age   3
    - Oppositional defiant disorder and conduct disorder overview   3
- Depression, self-harm, and suicide risk  

    - Depressive symptoms recognition   2
    - Grief reactions and adjustment disorders   3
    - Non-suicidal self-injury (NSSI)   3
    - Suicide risk assessment and safety planning   3
    - Treatment basics (therapy and SSRIs)   3

####  Psychosocial pediatrics and systems of care 

   57   

  Family systems, trauma, social stressors, cultural considerations, school collaboration, and integra...

         - Family systems and parenting support  

    - Caregiver burnout and support services   2
    - Divorce, custody, and blended families (overview)   3
    - Family assessment in pediatrics   3
    - Parenting styles and counseling   3
    - Siblings and chronic illness impact   2
- Substance use and risk behaviors (intro)  

    - Internet safety and digital wellbeing   3
    - Opioid exposure and overdose prevention (overview)   3
    - Sexual risk behaviors and consent (overview)   3
    - Substance use screening in adolescents   3
    - Vaping, cannabis, and alcohol counseling   4
- School collaboration and educational systems interface  

    - Behavior plans and communication with educators   4
    - Bullying, cyberbullying, and peer conflict   3
    - IEP/504 and clinician role (overview)   2
    - Learning disorders and neuropsych testing referral   3
    - School avoidance and refusal   2
- Trauma-informed care and adverse childhood experiences (ACEs)  

    - Recognizing trauma exposure and symptoms   3
    - Resilience-building and protective factors   3
    - Screening and referral to mental health resources   2
    - Special populations (foster care, refugees)   4
    - Trauma-informed communication principles   2

###  Growth And Development 

   169 questions   

####  Behavioral development and parenting counseling 

   55   

  Developmentally appropriate counseling, temperament, attachment, sleep/feeding norms, and behavior m...

         - Temperament and attachment  

    - Attachment development and disruption   3
    - Counseling in diverse family structures   3
    - Parent–child interaction assessment   3
    - Postpartum mental health effects on child development   2
    - Temperament traits and goodness-of-fit   3
- Toilet training and elimination development  

    - Encopresis and constipation linkage   3
    - Enuresis basics (developmental context)   3
    - Normal urinary frequency patterns   3
    - Red flags in elimination   3
    - Toilet training readiness and approaches   3
- Discipline strategies and behavioral management counseling  

    - Bullying and peer conflict counseling   2
    - Positive parenting and reinforcement   3
    - Screen time and media counseling   2
    - Temper tantrums and normal opposition   3
    - Time-out and limit setting   2
- Sleep development and sleep hygiene counseling  

    - Behavioral insomnia of childhood   3
    - Night terrors and parasomnias   3
    - Normal sleep needs by age   3
    - Safe sleep counseling   3
    - Sleep-disordered breathing red flags   2

####  Developmental milestones and neurodevelopment 

   70   

  Age-appropriate milestone acquisition, screening, and early identification of developmental disorder...

         - Developmental screening and surveillance  

    - Common screening tools (conceptual familiarity)   3
    - Cultural and socioeconomic considerations   3
    - Early intervention pathways   3
    - Hearing and vision contributions to delay   3
    - Surveillance vs screening (concept)   3
- Global developmental delay and intellectual disability evaluation  

    - Comorbidity screening and management   3
    - Etiology categories and prognosis counseling   3
    - History and exam approach   3
    - Initial investigations (evidence-based)   2
    - Neuroimaging indications   2
- Milestones across domains (gross motor, fine motor, language, social)  

    - Developmental red flags and urgent referral triggers   3
    - Fine motor and vision-dependent skills   2
    - Gross motor milestones   3
    - Language milestones (receptive and expressive)   3
    - Social-emotional and play development   3
- Motor development and neuromotor disorders (intro)  

    - Cerebral palsy (CP) basics   3
    - Developmental coordination disorder (overview)   3
    - Gross motor delay evaluation   3
    - Hypotonia approach   4
    - Toe walking differential   2
- Speech/language and learning issues  

    - Counseling families and coordinating supports   2
    - Executive function development   3
    - Language delay differential diagnosis   3
    - Learning disorders and school performance   2
    - Stuttering and speech sound disorders   3

####  Normal growth and physical maturation 

   44   

  Principles of normal somatic growth, puberty, and interpretation of pediatric anthropometrics.

         - Anthropometrics and growth chart interpretation  

    - BMI and weight-for-length in pediatrics   4
    - Bone age fundamentals   4
    - Growth velocity and pattern recognition   2
    - Mid-parental height and familial short stature   2
    - Weight, length/height, head circumference standards   3
- Normal physical exam findings by age  

    - Adolescent normal variants   3
    - Infant and toddler exam nuances   3
    - Newborn normal variants   3
    - Normal neurologic exam development   3
    - Red flags requiring urgent evaluation   3
- Puberty and sexual maturation (Tanner staging)  

    - Delayed puberty evaluation   2
    - Disorders of sex development (DSD) overview   3
    - Menstrual physiology and normal variation   2
    - Normal puberty timing and sequence   3
    - Precocious puberty evaluation   4

###  Infectious And Immune Disorders 

   180 questions   

####  Antimicrobial stewardship and infection control 

   45   

  Choosing antibiotics appropriately, preventing resistance, and applying infection prevention practic...

         - Primary immunodeficiency and allergy/anaphylaxis (clinical)  

    - Anaphylaxis diagnosis and management   3
    - Evaluation of suspected immunodeficiency   3
    - Food allergy evaluation and counseling (core)   2
    - Recurrent infections: common mimics and pitfalls   3
    - Urticaria and angioedema approach   3
- Principles of antimicrobial stewardship  

    - Antibiotic allergy evaluation and delabeling (conceptual)   2
    - Antibiotic-associated adverse events   3
    - Diagnostic stewardship   2
    - Duration of therapy concepts   3
    - Narrowing therapy based on cultures   4
- Standard and transmission-based precautions  

    - Contact, droplet, airborne isolation   4
    - Hand hygiene and PPE   3
    - Healthcare-associated infections (HAI) overview   3
    - Outbreak management in clinics and schools   4
    - Post-exposure prophylaxis for select infections   3

####  Approach to fever and serious bacterial infection 

   44   

  Risk stratification and management of febrile infants/children, sepsis evaluation, and core inpatien...

         - Bacterial meningitis and encephalitis (core)  

    - Clinical presentation by age and red flags   3
    - Complications and follow-up   3
    - CSF interpretation basics   3
    - Empiric therapy principles (conceptual)   3
    - Lumbar puncture indications and contraindications   2
- Fever in neonates and young infants (0–60/90 days)  

    - Empiric antimicrobial therapy (conceptual)   4
    - Evaluation components   4
    - Follow-up and culture monitoring systems   2
    - Risk stratification principles (conceptual)   2
    - Special scenarios   3
- Fever without source in older infants/children  

    - Fever in special hosts   3
    - Occult bacteremia era concepts   2
    - Prolonged fever and fever of unknown origin (FUO) overview   3
    - Sepsis recognition and management   3
    - UTI as common source   4

####  Common pediatric infections by syndrome 

   91   

  Board-relevant infectious syndromes across systems: respiratory, GI, urinary, skin, bone/joint, CNS,...

         - Bone and joint infections  

    - Differential diagnoses (malignancy, inflammatory)   3
    - Kingella kingae considerations   3
    - Lyme arthritis (regional)   2
    - Osteomyelitis   3
    - Septic arthritis   3
- Gastrointestinal infections and dehydration  

    - Acute viral gastroenteritis   4
    - Bacterial enteritis and dysentery   3
    - C. difficile infection (overview)   3
    - Parasitic diarrhea (Giardia)   3
    - Viral hepatitis overview in children   4
- Lower respiratory infections (pneumonia, pertussis, TB overview)  

    - Aspiration pneumonia and chronic lung disease infection considerations   3
    - Community-acquired pneumonia management   3
    - Influenza and antiviral use   4
    - Pertussis   3
    - Tuberculosis (TB) basics   2
- Skin and soft tissue infections  

    - Abscess and community-associated MRSA   3
    - Bite wounds and prophylaxis   3
    - Impetigo and cellulitis   3
    - Lymphangitis and systemic infection clues   2
    - Varicella and HSV skin manifestations   3
- Upper respiratory infections and pharyngitis  

    - Acute otitis media and otitis externa   5
    - Cervical lymphadenitis and deep neck space infections   2
    - Infectious mononucleosis   3
    - Streptococcal pharyngitis   3
    - Viral URI vs bacterial features   3
- Urinary tract infections  

    - Diagnosis and urine collection methods   3
    - Imaging after first febrile UTI (conceptual)   3
    - Recurrent UTI prevention   2
    - Treatment strategies and duration concepts   4
    - UTI in neonates and special hosts   3

###  Neonatal And Perinatal Care 

   143 questions   

####  Common neonatal problems and early infancy presentations 

   86   

  High-frequency neonatal conditions: jaundice, feeding issues, infections, respiratory problems, cong...

         - Common neonatal respiratory presentations  

    - Apnea in the newborn period   2
    - Meconium aspiration syndrome (MAS)   2
    - Neonatal pneumonia and sepsis overlap   2
    - Persistent pulmonary hypertension of the newborn (PPHN) overview   3
    - Transient tachypnea of the newborn (TTN)   3
- Congenital anomalies recognized at birth (core)  

    - Cardiac anomalies suspicion and initial steps   2
    - Congenital diaphragmatic hernia (CDH) overview   3
    - GI obstruction presentations   3
    - Neural tube defects and sacral anomalies   3
    - Orofacial clefts and feeding/airway issues   2
- Early-onset and late-onset neonatal sepsis (principles)  

    - Clinical presentation and evaluation   2
    - Empiric antibiotic choices (conceptual)   3
    - HSV infection recognition in neonate   2
    - Prevention strategies (GBS prophylaxis, hygiene)   4
    - Risk factors and typical organisms   2
- Neonatal feeding issues and weight loss  

    - Breastfeeding jaundice and breast milk jaundice   3
    - Cow’s milk protein allergy in infancy (overview)   3
    - Expected newborn weight loss and regain   3
    - Oral thrush and diaper dermatitis   4
    - Vomiting in the neonate (differential)   3
- Neonatal jaundice and hyperbilirubinemia management  

    - Exchange transfusion (overview)   4
    - Kernicterus and neurotoxicity risk   3
    - Phototherapy principles   3
    - Physiologic vs pathologic jaundice   3
    - Workup for hemolysis and cholestasis   3
- Safe discharge planning and early follow-up  

    - Discharge readiness criteria   3
    - Early outpatient follow-up planning   3
    - Maternal mental health and social supports (discharge context)   3
    - Parental counseling essentials   4
    - Special discharge for late preterm/SGA   3

####  Delivery room and immediate newborn care 

   57   

  Transition support, stabilization, and first hours of life care including resuscitation principles a...

         - Initial stabilization and neonatal resuscitation principles  

    - Chest compressions and epinephrine basics   2
    - Initial steps: warmth, airway positioning, stimulation   4
    - Positive pressure ventilation (PPV) fundamentals   3
    - Post-resuscitation care and disposition   2
    - Preparation and team roles   4
- Newborn physical exam and common normal variants  

    - Cardiac and respiratory exam findings   3
    - Genital exam and ambiguous genitalia first steps   2
    - Hip exam and musculoskeletal screening   2
    - Skin findings and birth trauma recognition   3
    - Vital signs and gestational age assessment   3
- Routine newborn prophylaxis and screening  

    - Critical congenital heart disease (CCHD) screen   2
    - Hyperbilirubinemia screening approach   2
    - Newborn hearing screening   3
    - Newborn metabolic screen follow-up   3
    - Vitamin K, eye prophylaxis, and hepatitis B vaccine   3
- Thermoregulation and glucose management in newborns  

    - Hyperglycemia in preterm/ill neonate (overview)   2
    - Hypothermia prevention and treatment   5
    - Monitoring and discharge safety checks   3
    - Neonatal hypoglycemia screening and thresholds (conceptual)   3
    - Polycythemia and hyperviscosity (overview)   3

###  Organ System Pediatrics 

   628 questions   

####  Cardiology 

   74   

  Common pediatric cardiac presentations, congenital and acquired heart disease, murmurs, cyanosis, ar...

         - Approach to heart murmur  

    - Associated symptoms and exam clues   3
    - Common congenital lesions (overview)   3
    - Endocarditis prophylaxis concepts   3
    - Innocent vs pathologic murmurs   3
    - Murmur timing and radiation interpretation   3
- Arrhythmias and syncope  

    - Bradycardia and heart block overview   4
    - Chest pain in pediatrics approach   3
    - Long QT and channelopathies (board overview)   4
    - SVT recognition and acute management   3
    - Syncope evaluation   3
- Cyanosis and congenital heart disease  

    - Central vs peripheral cyanosis evaluation   3
    - Cyanotic spells (TOF) management   3
    - Ductal-dependent lesions   3
    - Mixing lesions and parallel circulation   3
    - Pulmonary hypertension in pediatrics (overview)   2
- Heart failure and cardiomyopathy  

    - Arrhythmias causing cardiomyopathy (tachycardia-induced)   3
    - Clinical recognition in infants and children   3
    - Etiologies by age   3
    - Initial management principles   2
    - Myocarditis and pericarditis basics   2
- Hypertension and hyperlipidemia (core)  

    - Accurate BP measurement and interpretation   3
    - Dyslipidemia screening and management overview   4
    - Initial evaluation and management   3
    - Kawasaki disease coronary follow-up linkage   2
    - Secondary hypertension causes by age   3

####  Endocrinology 

   70   

  Diabetes, thyroid disease, adrenal disorders, growth disorders, puberty disorders, calcium/vitamin D...

         - Calcium/vitamin D and bone metabolism  

    - Bone health in chronic disease   3
    - Disorders of phosphate handling (overview)   3
    - Hypercalcemia differential (peds)   3
    - Hypocalcemia emergencies   3
    - Rickets and vitamin D deficiency   3
- Adrenal and pituitary disorders  

    - Adrenal insufficiency and adrenal crisis   2
    - Congenital adrenal hyperplasia (CAH) basics   2
    - Cushing syndrome overview   3
    - Diabetes insipidus vs SIADH (endocrine perspective)   2
    - Pituitary tumors and hypopituitarism overview   3
- Diabetes mellitus (type 1 and type 2)  

    - Diabetes technology (overview)   3
    - Diabetic ketoacidosis (DKA) basics   4
    - Hypoglycemia recognition and treatment   3
    - Type 1 diabetes presentation and diagnosis   3
    - Type 2 diabetes in youth overview   3
- Growth disorders and short/tall stature  

    - Growth hormone deficiency overview   3
    - Growth hormone therapy indications (overview)   3
    - Precocious and delayed puberty linkages   2
    - Short stature evaluation framework   3
    - Tall stature differential   3
- Thyroid disorders  

    - Acquired hypothyroidism (Hashimoto)   2
    - Congenital hypothyroidism   4
    - Hyperthyroidism (Graves) overview   3
    - Sick euthyroid syndrome pitfalls   2
    - Thyroid nodules and cancer risk (overview)   2

####  Gastroenterology and Hepatology 

   85   

  Abdominal pain, vomiting, diarrhea, constipation, GI bleeding, IBD overview, liver disease patterns,...

         - GI bleeding and anemia-related GI issues  

    - Intussusception and ischemic bleeding   3
    - Lower GI bleeding (hematochezia) approach   3
    - Occult blood and iron deficiency evaluation   2
    - Upper GI bleeding (hematemesis, melena) approach   4
    - Variceal bleeding and portal hypertension (overview)   3
- Hepatobiliary disease patterns  

    - Acute hepatitis and elevated transaminases   3
    - Cholestasis in infants   3
    - Gallstones and biliary colic (pediatrics)   2
    - Liver synthetic dysfunction and coagulopathy   3
    - Nonalcoholic fatty liver disease (NAFLD) overview   3
- Approach to abdominal pain  

    - Biliary and pancreatic pain (overview)   2
    - Constipation-related pain   3
    - Functional abdominal pain disorders (FAPD)   3
    - Inflammatory causes (IBD) suspicion   3
    - Red flags and urgent surgical causes   3
- Constipation and encopresis  

    - Disimpaction strategies   2
    - Encopresis and psychosocial impact   2
    - Functional constipation diagnosis and red flags   3
    - Maintenance therapy and relapse prevention   2
    - Secondary causes (Hirschsprung, hypothyroid, celiac)   3
- Diarrhea and malabsorption  

    - Acute diarrhea evaluation and ORT   4
    - Celiac disease   2
    - Lactose intolerance and carbohydrate malabsorption   4
    - Persistent/chronic diarrhea differential   3
    - Protein-losing enteropathy (overview)   2
- Vomiting and GERD  

    - Antiemetics and dehydration management   3
    - Gastroesophageal reflux (GER) vs GERD   2
    - Increased ICP and systemic causes of vomiting   3
    - Rumination and eating disorder-related vomiting (overview)   3
    - Vomiting differential by age (non-bilious vs bilious)   4

####  Hematology and Oncology 

   62   

  Anemias, hemoglobinopathies, bleeding disorders, thrombosis, leukemias/lymphomas (recognition), and...

         - Approach to anemia in children  

    - Hemolytic anemia overview   3
    - Iron deficiency anemia management   3
    - MCV-based differential diagnosis   4
    - Reticulocyte count interpretation   3
    - Transfusion decisions (anemia)   4
- Bleeding and clotting disorders  

    - Approach to bruising and bleeding   4
    - Coagulation test interpretation   3
    - Hemophilia and von Willebrand disease   3
    - ITP and thrombocytopenia evaluation   3
    - Thrombosis and anticoagulation basics (overview)   4
- Hemoglobinopathies and sickle cell disease  

    - Acute chest syndrome and vaso-occlusive crises   3
    - Newborn screening and counseling   3
    - Sickle cell disease baseline management   4
    - Splenic sequestration and aplastic crisis   2
    - Thalassemia overview   3
- Leukemia/lymphoma recognition and oncologic emergencies  

    - CBC abnormalities suggesting leukemia   2
    - Febrile neutropenia principles   2
    - Mediastinal mass syndrome   2
    - Red flags for malignancy in children   3
    - Tumor lysis syndrome (TLS)   4

####  Nephrology and Urology 

   74   

  Hematuria/proteinuria, nephrotic/nephritic syndromes, AKI, electrolytes, UTI imaging, congenital ano...

         - Acute kidney injury (AKI) and chronic kidney disease (CKD) overview  

    - AKI definitions and staging (conceptual)   3
    - AKI initial management   3
    - CKD complications (overview)   3
    - Dialysis and transplant basics (board overview)   3
    - Postrenal obstruction recognition   3
- Congenital anomalies of kidney and urinary tract (CAKUT) and voiding disorders  

    - Antenatal hydronephrosis and postnatal evaluation   3
    - Enuresis and bladder/bowel dysfunction   3
    - Posterior urethral valves (PUV)   3
    - UTI prevention counseling and hygiene   3
    - Vesicoureteral reflux (VUR) overview   3
- Hematuria evaluation  

    - Common glomerular causes   3
    - Glomerular vs non-glomerular sources   2
    - Microscopic vs gross hematuria   3
    - Referral criteria to nephrology/urology   3
    - Stones and hypercalciuria (overview)   3
- Nephritic syndromes and glomerulonephritis  

    - Acute post-streptococcal GN   3
    - Hypertensive urgency in nephritic syndrome   2
    - IgA nephropathy / IgA vasculitis nephritis   3
    - Membranoproliferative GN and complement disorders (overview)   3
    - Rapidly progressive GN (RPGN) overview   3
- Proteinuria and nephrotic syndrome  

    - Complications and prophylaxis   3
    - Nephrotic syndrome (minimal change) presentation   3
    - Screening and quantification   3
    - Steroid therapy principles and response monitoring   4
    - When to biopsy and refer   3

####  Neurology 

   60   

  Headache, seizures, developmental neurology, neuromuscular disorders, and common neurologic emergenc...

         - Neurodevelopmental and movement disorders (core overview)  

    - Ataxia differential   3
    - Cerebral palsy recognition and classification   3
    - Dystonia and chorea (overview)   3
    - Neurocutaneous syndromes (overview)   3
    - Tics and Tourette syndrome   3
- Headache and migraine  

    - Acute migraine management   2
    - Idiopathic intracranial hypertension overview   3
    - Preventive therapy overview   3
    - Primary headache types in children   4
    - Secondary headache red flags   4
- Neuromuscular weakness and hypotonia  

    - Central vs peripheral hypotonia differentiation   2
    - Guillain–Barré syndrome (GBS) basics   3
    - Muscular dystrophy and Gowers sign   3
    - Myasthenia gravis and botulism overview   4
    - Spinal muscular atrophy (overview)   3
- Seizure disorders and epilepsy (outpatient framework)  

    - Antiseizure medications: common adverse effects   4
    - Common epilepsy syndromes (board overview)   3
    - Febrile seizures counseling   2
    - Initial evaluation after first unprovoked seizure   3
    - Seizure classification basics   2

####  Pulmonology and Sleep 

   74   

  Wheezing disorders, asthma, chronic cough, pneumonia, CF overview, sleep-disordered breathing, and p...

         - Sleep-disordered breathing and pediatric sleep disorders (core)  

    - Evaluation and polysomnography concepts   3
    - Management pathways   3
    - Obstructive sleep apnea (OSA) recognition   2
    - Parasomnias and restless sleep   3
    - Sleep hygiene counseling in pediatrics   4
- Asthma diagnosis and long-term management  

    - Asthma diagnosis criteria and differential   4
    - Asthma education and inhaler technique   4
    - Severe asthma and referral indications   2
    - Stepwise controller therapy (conceptual)   3
    - Trigger management and comorbidities   4
- Bronchiolitis, recurrent wheeze, and early childhood wheezing phenotypes  

    - Bronchiolitis supportive care and complications   4
    - Chronic lung disease of prematurity (overview)   2
    - Episodic viral wheeze vs early asthma   3
    - Foreign body aspiration   2
    - Stridor and upper airway disorders   4
- Chronic cough and recurrent respiratory infections  

    - Aspiration and swallowing dysfunction   3
    - Cough duration approach (acute/subacute/chronic)   3
    - Cystic fibrosis overview and screening linkage   2
    - Immunodeficiency linkage and evaluation triggers   2
    - Primary ciliary dyskinesia (overview)   3
- Pneumonia, pleural effusion, and empyema  

    - Atypical and aspiration pneumonia   3
    - CAP diagnosis and outpatient/inpatient decisions   3
    - Complicated pneumonia (effusion/empyema)   3
    - Necrotizing pneumonia and lung abscess (overview)   2
    - Recurrent pneumonia evaluation   3

####  Rheumatology 

   129   

  Common inflammatory disorders, vasculitis, arthritis, periodic fever syndromes overview, and managem...

         - SLE and systemic autoimmune disease (overview)  

    - Autoantibody testing and interpretation   3
    - Lupus nephritis overview   3
    - Medication adverse effects and monitoring   4
    - Pediatric SLE presentation patterns   4
    - Vasculitis and connective tissue diseases (board overview)   3
- Dermatology  

    - Acne and adolescent dermatology basics   3
    - Atopic dermatitis and eczema management   3
    - Common pediatric rashes and exanthems   4
    - Hemangiomas and vascular lesions (overview)   4
    - Neonatal skin conditions   3
    - Skin findings suggesting systemic disease   3
    - Urticaria, angioedema, and drug rashes   3
- ENT and Ophthalmology  

    - Conjunctivitis and eye emergencies   3
    - Dizziness/vertigo in children (overview)   4
    - Epistaxis and nasal obstruction   3
    - Hearing loss evaluation basics   3
    - Otitis media with effusion and recurrent AOM   4
    - Pharyngitis and peritonsillar/retropharyngeal abscess   4
    - Vision screening abnormalities and amblyopia prevention   3
- IgA vasculitis (Henoch–Schönlein purpura)  

    - Clinical features and diagnosis   3
    - Complications   2
    - Differential diagnosis of purpura   3
    - Renal involvement monitoring   3
    - Treatment and indications for steroids   2
- Juvenile idiopathic arthritis (JIA)  

    - Initial treatment principles   3
    - JIA subtypes and presentation patterns   3
    - Rehabilitation and functional outcomes   3
    - Systemic JIA and MAS (overview)   3
    - Uveitis screening   2
- Kawasaki disease  

    - Coronary artery aneurysm follow-up   4
    - Diagnostic criteria and incomplete Kawasaki   4
    - Kawasaki shock syndrome (overview)   3
    - MIS-C vs Kawasaki differentiation (overview)   2
    - Treatment (IVIG and aspirin)   3
- Musculoskeletal and Orthopedics  

    - Bone metabolism and fracture risk (overview)   3
    - Developmental dysplasia of the hip (DDH)   4
    - Limping child evaluation   3
    - SCFE and adolescent hip pain   3
    - Scoliosis and back pain red flags   3
    - Septic arthritis and osteomyelitis   3
    - Sports injuries and overuse (overview)   3

###  Preventive And Community Care 

   141 questions   

####  Community pediatrics and population health 

   61   

  Social determinants of health, health equity, school health, community resources, public health prin...

         - Child advocacy and public health policy (board overview)  

    - Disaster preparedness and emergency planning for families   3
    - Global child health (core concepts)   4
    - Immigrant/refugee child health basics   5
    - Public insurance and access to care concepts   3
    - Screening programs and population interventions   3
- Care delivery systems in ambulatory pediatrics  

    - Chronic disease management in the community   3
    - Medical home and care coordination   2
    - Population health metrics and quality measures (overview)   3
    - Telehealth and remote monitoring (overview)   4
    - Vaccination storage and clinic operations safety   2
- School health and learning environment  

    - Attendance, chronic absenteeism, and health   3
    - Behavioral health integration with schools   3
    - Infectious disease control in schools   3
    - School physicals and participation forms   3
    - Special education supports (overview)   3
- Social determinants of health (SDOH) screening and intervention  

    - Food insecurity and nutrition access   3
    - Housing instability and environmental risk   3
    - Language access and health literacy   3
    - Racism, bias, and equity in child health   3
    - Transportation and access barriers   2

####  Health supervision and preventive counseling 

   80   

  Well-child care schedules, anticipatory guidance, screening, injury prevention, and age-based counse...

         - Adolescent preventive care and risk reduction  

    - Confidentiality and consent in adolescent care (preventive framing)   3
    - Eating disorders and body image screening   3
    - Sexual and reproductive health screening and counseling   4
    - Substance use prevention and intervention   4
    - Violence, bullying, and relationship safety   3
- Immunizations (routine and special situations)  

    - Catch-up immunization strategies   3
    - Post-exposure prophylaxis and outbreak vaccination   3
    - Routine childhood immunization principles   2
    - Special populations (immunocompromised, pregnancy exposure, asplenia)   4
    - Vaccine hesitancy counseling   2
- Injury prevention and safety counseling  

    - Drowning prevention   5
    - Firearm injury prevention   3
    - Motor vehicle safety   4
    - Poisoning prevention   3
    - Sports and recreation safety   3
- Screening in primary care (age-appropriate)  

    - Anemia/lead and other lab screening   3
    - Hearing screening   4
    - Mental health and substance use screening   3
    - Newborn screening and early infancy preventive care   3
    - Vision screening   3
- Well-child visit structure and age-based priorities  

    - Anticipatory guidance frameworks   3
    - Care coordination and follow-up planning   3
    - Developmental/behavioral surveillance integration   3
    - Periodic health supervision timing (conceptual schedule)   3
    - Vital signs and growth monitoring   3

###  Professional Practice 

   276 questions   

####  Communication, Teamwork, and Patient-Centered Care 

   26   

  Core communication behaviors, empathy under pressure, and effective teamwork.

         - Patient-centered communication in the ED  

    - Agenda setting and expectation management   3
    - Communicating uncertainty and risk   3
    - Cross-cultural communication   3
    - Delivering difficult news (foundational)   2
    - Managing challenging interactions   3
- Teamwork and leadership basics  

    - Closed-loop communication   2
    - Conflict management basics   2
    - Debriefing and reflective practice (intro)   2
    - Handover and transitions   3
    - Situational awareness and workload management   3

####  Ethics, Consent, and Legal Interfaces 

   39   

  Foundational professional obligations, capacity, consent, and ED medicolegal responsibilities.

         - Consent and decision-making capacity  

    - Capacity assessment framework   2
    - Informed consent in the ED   3
    - Refusal of care and AMA discharge   2
    - Resuscitation status and goals-of-care basics   3
    - Surrogate decision-makers and minors   4
- Documentation Standards and Risk Management  

    - Avoiding biased/stigmatizing language   2
    - Handover documentation   3
    - Medical decision making (MDM) clarity   3
    - Procedure documentation   2
    - Results follow-up and callbacks   3
- Mandatory reporting and safeguarding duties  

    - Child abuse reporting   2
    - Death certification and coroner/ME interface (awareness)   2
    - Fitness to drive/duty to warn (contextual awareness)   2
    - Reportable infectious diseases (awareness)   2
    - Sexual assault and IPV documentation   4

####  Ethics, law, and professional responsibilities 

   90   

  Consent/assent, confidentiality, decision-making standards, safeguarding/reporting obligations, and...

         - Research literacy and statistics for clinicians  

    - Critical appraisal of medical literature   3
    - Data safety and privacy (overview)   3
    - Ethics in research and publication   3
    - Interpreting common statistical outputs   4
    - Practice improvement through audit (overview)   3
- Child protection duties and reporting (core professional practice)  

    - Communication with caregivers in suspected abuse   2
    - Mandatory reporting principles   3
    - Medical mimics and avoiding diagnostic error   4
    - Professional boundaries and self-care after difficult cases   3
    - Recognizing possible abuse and neglect (overview)   3
- Communication skills and professionalism  

    - Conflict resolution and teamwork   3
    - Cultural humility and cross-cultural communication   3
    - Delivering difficult news and serious illness communication   3
    - Documentation and medicolegal quality   3
    - Professionalism lapses and remediation awareness   3
- Confidentiality and privacy in adolescent care  

    - Creating confidential time in visits   3
    - Electronic communication professionalism   3
    - Information sharing with schools and agencies   2
    - Mandatory disclosure exceptions   2
    - Sensitive services (sexual health, mental health, substance use)   2
- Consent, assent, and capacity in pediatrics  

    - Mature minor and emancipated minor concepts (jurisdiction-dependent)   3
    - Parental permission vs child assent   4
    - Refusal of treatment and best interest standard   3
    - Research consent in minors (overview)   3
    - Shared decision-making and informed consent elements   4
- Quality, safety, and clinical governance  

    - Error disclosure and apology   3
    - Infection prevention and antimicrobial stewardship (professional practice)   3
    - Medication and diagnostic safety in pediatrics   3
    - Patient safety fundamentals   3
    - Quality improvement (QI) methods   3

####  Ethics, Law, Consent &amp; Safeguarding 

   75   

  Professional standards for consent, confidentiality, capacity, boundaries, documentation, reporting,...

         - Confidentiality, privacy, and mandated reporting concepts  

    - Adolescent confidentiality (principles)   2
    - Confidentiality principles in sexual and reproductive care   3
    - Human trafficking awareness   3
    - Mandatory reporting (conceptual, jurisdiction-dependent)   3
    - Safeguarding: IPV and sexual violence   3
- Evidence-Based Practice, Research Literacy &amp; Guideline Use  

    - Applying guidelines to individuals   3
    - Clinical ethics in evidence translation   2
    - Critical appraisal of clinical studies   3
    - Research integrity and publication ethics   3
    - Statistics commonly tested   3
- Informed consent and refusal of care  

    - Consent for learners and sensitive exams   4
    - Consent in emergencies   2
    - Elements of informed consent   4
    - Procedural consent specifics   4
    - Refusal of recommended treatment   4
- Patient Safety, Quality Improvement, and Risk Management  

    - Clinical governance and incident reporting   3
    - Medicolegal risk reduction   3
    - Obstetric safety bundles (conceptual)   2
    - Quality improvement methods   3
    - Safety culture and error science   3
- Professionalism, Teamwork, Education &amp; Wellbeing  

    - Clinician wellbeing and burnout prevention   3
    - Equity, diversity, and respectful care   4
    - Interprofessional teamwork and communication   3
    - Professional boundaries and social media   2
    - Teaching and supervision (clinical educator basics)   3

####  Quality, Safety, and Systems (Foundational) 

   46   

  Basics of patient safety, quality improvement, infection control, and ED operations awareness.

         - ED operations and flow (intro)  

    - Consultation pathways and transfer   3
    - Discharge processes and health system navigation   3
    - Equity and access in ED care   3
    - Handoffs and staffing considerations   3
    - Throughput basics   4
- Professionalism, wellness, and boundaries  

    - Ethical prescribing and controlled substances   3
    - Fatigue, burnout, and error risk   3
    - Professional boundaries and social media awareness   2
    - Professional conduct and accountability   4
    - Teaching and supervision basics   3
- Patient safety fundamentals  

    - Diagnostic error mitigation   3
    - High-risk medications and dosing safety   2
    - Incident reporting and learning systems   3
    - Infection prevention and PPE   3
    - Violence prevention and workplace safety   4

  Pediatrics Advanced Pathway

###  Adolescent And Transition Care 

   121 questions   

####  Adolescent medicine and confidential care 

   83   

  Comprehensive adolescent health: confidentiality, sexual/reproductive health, substance use, mental...

         - Gender, identity, and adolescent psychosocial development (principles)  

    - Depression, anxiety, and suicide risk in adolescents   3
    - Gender diversity affirming care principles   3
    - Normal identity development and psychosocial tasks   3
    - Online safety and exploitation risks   2
    - Sexual orientation and minority stress (overview)   3
- Sports participation and adolescent health maintenance  

    - Concussion management and return-to-play/learn   3
    - Heat illness and hydration strategies   3
    - Injury prevention and overuse in adolescents   3
    - Preparticipation evaluation (PPE) and cardiac screening concepts   2
    - Substance use in sports (supplements, steroids)   3
- Confidentiality, consent, and communication in adolescent care  

    - Assessing decision-making capacity and risk   3
    - Cultural humility and inclusive care   3
    - Mandatory reporting and safety exceptions   2
    - Structuring the visit with private time   3
    - Transitioning responsibility from parents to youth   3
- Eating disorders and adolescent nutrition  

    - Anorexia nervosa and restrictive eating disorders   3
    - ARFID in adolescents (overview)   2
    - Athlete triad / RED-S (overview)   2
    - Body image, weight stigma, and counseling   3
    - Bulimia nervosa and purging behaviors   3
- Sexual and reproductive health  

    - Contraception counseling and provision (overview)   3
    - Menstrual disorders in adolescents (advanced overview)   3
    - Pregnancy testing and options counseling (overview)   2
    - Pubertal development and normal sexual health counseling   3
    - STI screening, diagnosis, and prevention   2
- Substance use and risk behaviors  

    - Alcohol use and poisoning risk   3
    - Nicotine/vaping and cannabis   3
    - Opioids and overdose prevention   3
    - Risky driving, violence, and legal risks   3
    - Screening and brief intervention   3

####  Transition to adult care for chronic disease 

   38   

  Structured transition planning, adherence, self-management skills, and handover for common pediatric...

         - Adherence, risk reduction, and psychosocial supports  

    - Emergency preparedness and self-advocacy   2
    - Medication adherence strategies   3
    - Mental health comorbidity screening   2
    - Reproductive health counseling in chronic disease   3
    - Social determinants and transition success   2
- Disease-specific transition considerations (selected)  

    - Congenital heart disease transition   3
    - Cystic fibrosis transition   3
    - Inflammatory bowel disease transition   3
    - Sickle cell disease transition   2
    - Type 1 diabetes transition   3
- Transition planning frameworks  

    - Handover communication and summaries   2
    - Health literacy and developmental considerations   4
    - Legal changes at age of majority   2
    - Quality metrics and barriers in transition (overview)   2
    - Readiness assessment and milestones   2

###  Advanced Basic Sciences 

   92 questions   

####  Advanced cardiopulmonary physiology and monitoring 

   38   

  Deeper physiologic reasoning for high-acuity scenarios: ventilation/perfusion, mechanics, hemodynami...

         - Advanced fluids, electrolytes, and acid–base  

    - Complex acid–base analysis   3
    - DKA electrolyte and osmolality management nuances   3
    - Hyponatremia management in CNS disease and SIADH   2
    - Massive transfusion and coagulopathy physiology   2
    - Renal replacement therapy effects on electrolytes/drugs (overview)   3
- Advanced respiratory mechanics and ventilation strategies  

    - Compliance, resistance, and time constants   3
    - Gas exchange and oxygenation indices   2
    - Noninvasive respiratory support escalation   2
    - Permissive hypercapnia and lung-protective ventilation   2
    - Ventilator modes and settings (conceptual mastery)   3
- Hemodynamics, shock physiology, and vasoactive pharmacology  

    - Fluid responsiveness and overload harm   3
    - Hemodynamic profiles and bedside assessment   2
    - Microcirculation and lactate kinetics   2
    - Post-cardiac arrest physiology overview   3
    - Vasoactive agents selection principles   3

####  Advanced clinical pharmacology and therapeutics 

   54   

  Complex dosing, drug interactions, organ dysfunction dosing, sedation/analgesia strategies, and anti...

         - Evidence appraisal and diagnostic reasoning (advanced)  

    - Advanced diagnostic test interpretation   3
    - Clinical prediction models and calibration   2
    - Critical care research literacy (overview)   2
    - Diagnostic error and cognitive debiasing   3
    - Guideline appraisal and applying to complex patients   3
- Antimicrobial optimization and complex infections (advanced principles)  

    - Antibiotic resistance mechanisms (board-relevant)   3
    - Antifungal and antiviral therapeutics (advanced overview)   4
    - Broad-spectrum selection and de-escalation   3
    - Pharmacodynamics and dosing strategies   2
    - Source control and ID consultation triggers   3
- Drug dosing in organ dysfunction (renal/hepatic)  

    - Drug–drug interactions in pediatrics   3
    - Hepatic dysfunction dosing considerations   2
    - Obesity dosing strategies   2
    - Renal dosing adjustments   3
    - Therapeutic drug monitoring (advanced)   3
- Sedation, analgesia, and delirium in critically ill children  

    - Analgesia-first sedation concept   2
    - Neuromuscular blockade (NMB) overview   3
    - Pediatric delirium recognition and management   3
    - Sedative agents selection and adverse effects   3
    - Withdrawal and weaning   2

###  Child Protection And Safeguarding 

   69 questions   

####  Recognition and medical evaluation of maltreatment 

   69   

  Physical, sexual, emotional abuse and neglect recognition, differential diagnosis, documentation, re...

         - Maltreatment mimics and special considerations  

    - Accidental injury patterns and developmental plausibility   3
    - Bleeding disorders workup in concerning bruising   2
    - Bone disease mimics   3
    - Dermatologic mimics of injury   3
    - Safeguarding in children with disability and communication barriers   2
- Documentation, reporting, and legal processes  

    - Bias, equity, and avoiding disparities in reporting   3
    - Court testimony basics (overview)   3
    - High-quality medical documentation for safeguarding cases   3
    - Mandatory reporting workflow and collaboration   2
    - Trauma-informed care for child and family   3
- Neglect, medical neglect, and emotional abuse  

    - Emotional abuse and exposure to domestic violence   3
    - Failure to thrive and neglect interface   2
    - Medical neglect   2
    - Physical neglect and unsafe environments   3
    - Substance-exposed caregiving and safeguarding   3
- Physical abuse recognition and injury pattern analysis  

    - Abusive head trauma (AHT) recognition   3
    - Bruising patterns and sentinel injuries   3
    - Burns and scald injuries   3
    - Differential diagnosis and medical mimics   4
    - Fractures suspicious for abuse   2
- Sexual abuse evaluation (medical aspects)  

    - History-taking principles and forensic interface   3
    - Mandatory reporting and multidisciplinary coordination   3
    - Physical exam principles and limitations   2
    - Sex trafficking and exploitation recognition (overview)   3
    - STI testing and prophylaxis concepts   3

###  Complex And Palliative Care 

   117 questions   

####  Children with medical complexity and technology dependence 

   60   

  Longitudinal management of medically complex children, coordination across settings, and safe care o...

         - Care coordination and the medical home for complexity  

    - Complex care planning and shared goals   3
    - Health equity and caregiver burden   3
    - Medication and equipment reconciliation   2
    - Preventive care adaptations in complex children   3
    - Transitions across settings (hospital-home-school)   4
- Enteral feeding tubes and nutrition support  

    - Aspiration risk and feeding regimens   3
    - Ethical issues in long-term tube feeding   2
    - Gastrostomy and jejunostomy tube care   2
    - Nutrition monitoring and complications   3
    - Short bowel and intestinal failure (overview)   3
- Neurologic complexity (severe epilepsy, neuromuscular disease)  

    - Caregiver support and respite   4
    - Communication impairment supports   4
    - Neuromuscular respiratory failure planning   3
    - Refractory epilepsy care planning   3
    - Spasticity, dystonia, and pain management   3
- Tracheostomy and chronic respiratory support  

    - Airway clearance and secretion management   2
    - Chronic ventilation (invasive and noninvasive)   4
    - Family training, emergency plans, and community integration   4
    - Respiratory infections and antibiotic decisions in trach patients   2
    - Routine tracheostomy care and complications   3

####  Pediatric palliative care and symptom management 

   57   

  Symptom control, communication, ethical decision making, and end-of-life care including bereavement...

         - Core principles of pediatric palliative care  

    - Assessing goals, values, and quality of life   3
    - Communication in serious illness   3
    - Cultural and spiritual considerations   4
    - Ethics: withholding/withdrawing life-sustaining treatment   3
    - Palliative care vs hospice distinctions   3
- End-of-life care and bereavement  

    - After-death care and legal documentation (overview)   2
    - Bereavement support   3
    - Clinician wellbeing and debriefing   2
    - Location of death planning (home/hospital/hospice)   4
    - Recognizing dying trajectory and preparing families   3
- Non-pain symptom management  

    - Agitation and delirium in palliative settings   3
    - Dyspnea management   2
    - Nausea/vomiting and constipation   3
    - Secretion management   2
    - Seizures at end of life   2
- Pain management in palliative care  

    - Adjuvant analgesics   3
    - Opioid stewardship and risk mitigation   3
    - Opioid therapy principles   3
    - Pain assessment in nonverbal children   2
    - Procedural and acute pain episodes   4

###  Critical And Emergency Care 

   93 questions   

####  High-acuity resuscitation and ICU syndromes 

   93   

  Advanced management of shock, respiratory failure, severe neurologic emergencies, DKA, toxicology, t...

         - Advanced airway and mechanical ventilation in ICU/ED  

    - ARDS and severe hypoxemia strategies   3
    - Difficult airway rescue and failed airway algorithms   2
    - Post-intubation management   3
    - Rapid sequence intubation (RSI) planning   3
    - Status asthmaticus ventilation pitfalls   3
- Crisis resource management (CRM) and systems skills  

    - Ethics in critical care decisions (overview)   2
    - Handoffs, transport, and escalation   3
    - Human factors and error prevention in ICU/ED   3
    - Procedural competence and complication management   3
    - Team leadership and communication in resuscitation   3
- DKA, HHS, and endocrine emergencies in critical care  

    - Adrenal crisis and severe hypoglycemia   2
    - Cerebral edema recognition and treatment   3
    - DKA protocol nuances (advanced)   3
    - Hyperosmolar hyperglycemic state (HHS) in youth (overview)   2
    - Thyroid storm and myxedema (rare)   2
- Neurologic critical care: status epilepticus, ICP, coma  

    - Coma evaluation in ICU   2
    - Increased intracranial pressure and herniation management   2
    - Post-cardiac arrest care (overview)   3
    - Refractory status epilepticus management   2
    - Sedation confounders and brain death basics (overview)   4
- Septic shock advanced management  

    - Adjunctive therapies and source control   3
    - Complications (DIC, AKI, ARDS)   3
    - Early recognition and time-sensitive interventions   3
    - Monitoring and endpoints of resuscitation   3
    - Vasoactive choice tailoring   2
- Toxicology and environmental emergencies (advanced)  

    - Envenomation and toxic exposures (overview)   3
    - High-risk cardiovascular toxin ingestions   3
    - Serotonin syndrome vs NMS   2
    - Severe acetaminophen and salicylate poisoning   3
    - Toxic alcohols and metabolic acidosis   3
- Trauma critical care and hemorrhage control  

    - Abdominal trauma and solid organ injury management   2
    - Massive hemorrhage and transfusion strategy (conceptual)   2
    - Severe traumatic brain injury (TBI) principles   2
    - Spinal cord injury and neurogenic shock   3
    - Thoracic trauma and tension pneumothorax   3

###  Developmental And Behavioral Pediatrics 

   65 questions   

####  Neurodisability and complex developmental medicine 

   65   

  Cerebral palsy, intellectual disability, complex ASD/ADHD, sleep/feeding disorders, multidisciplinar...

         - Feeding disorders and ARFID (advanced overview)  

    - Aspiration and oropharyngeal dysphagia management   3
    - Avoidant/restrictive food intake disorder (ARFID)   3
    - Family-centered counseling and caregiver stress   2
    - Pediatric feeding disorder framework   2
    - Tube feeding and weaning principles   3
- Autism and neurodevelopmental differences (advanced)  

    - Behavioral challenges (irritability, aggression)   3
    - Comprehensive evaluation in complex ASD   3
    - Family counseling and neurodiversity-affirming practice   3
    - School supports and transition planning   2
    - Sensory processing and OT interventions (overview)   2
- Cerebral palsy (CP) comprehensive management  

    - Classification and functional assessment   3
    - Feeding, nutrition, and aspiration management   3
    - Hip surveillance and orthopedic complications   3
    - Pain, sleep, and quality of life   2
    - Tone management strategies   4
- Complex ADHD and comorbidity management  

    - ADHD with anxiety/depression   2
    - ADHD with autism and developmental delay   3
    - ADHD with learning disorders and executive dysfunction   2
    - Substance use risk and diversion prevention   2
    - Tics and ADHD   3
- Sleep disorders in neurodevelopmental conditions  

    - Insomnia and circadian rhythm disorders   3
    - Medication contributors to sleep problems   2
    - Parasomnias vs nocturnal seizures   3
    - Restless sleep and iron deficiency   2
    - Sleep-disordered breathing in special populations   2

###  Genetics And Metabolism 

   98 questions   

####  Genetic testing, counseling, and dysmorphology (advanced) 

   29   

  Rational test selection, interpretation of results, genotype–phenotype reasoning, and ethical counse...

         - Dysmorphology and syndrome recognition (advanced set)  

    - Approach to multiple congenital anomalies   3
    - Common microdeletion/duplication syndromes (overview)   3
    - Connective tissue disorders (Marfan/EDS) overview   3
    - Genetic short stature syndromes (overview)   4
    - RASopathies overview   3
- Advanced test selection and interpretation  

    - Ethical issues: testing minors, carrier testing, and privacy   3
    - Microarray vs exome/genome vs targeted testing   2
    - Prenatal genetics interface (advanced overview)   4
    - Secondary findings and incidental results   2
    - Variant interpretation and counseling (VUS)   2

####  Inborn errors of metabolism (IEM) and metabolic emergencies 

   69   

  Recognition and immediate management of metabolic decompensation, plus core IEM categories and board...

         - Mitochondrial and lysosomal/peroxisomal disorders (overview)  

    - Lysosomal storage disorders overview   3
    - Mitochondrial disease red flags   3
    - Peroxisomal disorders overview   3
    - Porphyria awareness (rare but testable)   3
    - Supportive care and palliative considerations   3
- Organic acidemias  

    - Acute management concepts   3
    - Long-term management overview   4
    - Maple syrup urine disease (MSUD)   3
    - Methylmalonic acidemia specifics (overview)   3
    - Presentation and lab patterns   2
- Approach to acute metabolic decompensation  

    - Avoiding iatrogenic harm   2
    - Counseling and emergency plans for families   2
    - Hyperammonemia management   3
    - Initial stabilization and stopping catabolism   2
    - Key diagnostic labs (critical sample)   2
- Fatty acid oxidation disorders (FAOD)  

    - Acute management   2
    - Chronic management and prevention   3
    - Clinical presentation and hypoketotic hypoglycemia   2
    - Diagnostic testing and newborn screening   3
    - MCAD deficiency core board details   2
- Urea cycle disorders  

    - Acute management   3
    - Chronic management overview   4
    - Clinical presentation patterns   3
    - Diagnostic approach   3
    - Medication contraindications and perioperative planning   3

###  Leadership And Scholarship 

   131 questions   

####  Advocacy, policy, and professional identity 

   14   

  Advocacy for patients and populations, policy literacy, and maintaining professional wellbeing and s...

         - Mental health policy literacy (overview)  

    - Financing, parity, and service design concepts   3
- Advocacy for mental health equity  

    - Social determinants and structural stigma   3
- Professional wellbeing and sustaining a career  

    - Burnout prevention and boundaries   4
    - Ethics in leadership roles   4

####  Clinical leadership and service management 

   20   

  Leadership competencies for psychiatrists, including team management, change leadership, and resourc...

         - Change management and implementation  

    - Implementation science basics   3
- Leadership styles and team dynamics  

    - Interdisciplinary teamwork and delegation   5
    - Situational leadership and psychological safety   3
- Quality, safety, and governance in mental health services  

    - Clinical governance and incident review   5
    - Risk management at service level   4

####  Education, supervision, and assessment 

   17   

  Teaching skills, curriculum design, supervision, and assessment aligned with competency frameworks.

         - Curriculum and exam blueprint literacy  

    - Learning objectives and alignment   3
- Clinical teaching and feedback  

    - Bedside/clinic teaching models   4
    - Feedback and remediation   3
- Supervision and trainee assessment  

    - Entrustment and graded responsibility   3
    - Workplace-based assessments (overview)   4

####  Quality improvement, safety, and systems-based practice 

   60   

  QI methodology, patient safety event analysis, guideline implementation, stewardship, and leading te...

         - Research methods, teaching, and leadership  

    - Ethics, IRB, and dissemination   3
    - Feedback, coaching, and assessment   3
    - Leadership in clinical teams   4
    - Research design and statistics (advanced overview)   4
    - Teaching skills and curriculum design   3
- Resource stewardship and guideline implementation  

    - Antimicrobial stewardship programs (systems level)   2
    - Choosing tests and treatments wisely (value-based care)   3
    - Clinical pathways and standardization   2
    - Health informatics and clinical decision support (overview)   4
    - Implementation science basics (overview)   2
- Patient safety science and event analysis  

    - High reliability organization principles   3
    - Human factors and systems thinking   3
    - Medication safety and diagnostic safety initiatives   5
    - Root cause analysis (RCA) and action planning   3
    - Safety event reporting and just culture   3
- Quality improvement (QI) methods and measurement  

    - Building an aim statement and driver diagram   3
    - Equity in QI   2
    - Measurement for improvement   3
    - PDSA cycles and iterative testing   3
    - Sustainability and reliability   2

####  Scholarship, research methods, and critical appraisal (advanced) 

   20   

  Designing, appraising, and translating research; research governance and ethics.

         - Knowledge translation and guideline development (overview)  

    - From evidence to practice   3
- Advanced critical appraisal and statistics (applied)  

    - Causal inference and confounding control (overview)   5
    - Interpreting complex trial designs   4
- Research ethics and integrity  

    - Human subjects protections   4
    - Open science and reproducibility (overview)   4

###  Neonatal Intensive Care 

   85 questions   

####  Extreme prematurity and NICU stabilization 

   85   

  Advanced management of very preterm infants, stabilization, thermoregulation, respiratory support, h...

         - Delivery room care for extremely preterm infants  

    - Delayed cord clamping and placental transfusion   2
    - Family communication and shared decision-making   2
    - Initial vascular access and labs   3
    - Respiratory support at birth   2
    - Thermoregulation and prevention of heat loss   3
- Hemodynamics, PDA, and cardiovascular issues  

    - Anemia and transfusion thresholds in preterm infants (overview)   3
    - Congenital heart disease stabilization in NICU   3
    - Hypotension in preterm infants   3
    - Patent ductus arteriosus (PDA) management controversies (overview)   3
    - Persistent pulmonary hypertension of the newborn (PPHN) in NICU   3
- Neonatal infection, antimicrobial use, and transport  

    - Antibiotic stewardship in NICU   2
    - Congenital infections (TORCH) advanced overview   3
    - Ethics in extreme prematurity and limitation of support   3
    - Late-onset sepsis and central line infections   2
    - Neonatal transport and stabilization for transfer   2
- Neurologic complications and neuroprotection  

    - Hypoxic-ischemic encephalopathy (HIE) and therapeutic hypothermia   3
    - Intraventricular hemorrhage (IVH) and PVL   4
    - Neonatal seizures in NICU   3
    - Neonatal stroke and thrombosis (overview)   3
    - Pain/stress and developmental care in NICU   3
- Nutrition and GI complications in NICU  

    - Enteral feeding advancement and human milk use   3
    - GER and feeding intolerance in preterm infants (overview)   3
    - Necrotizing enterocolitis (NEC)   3
    - Parenteral nutrition (TPN) principles and complications   3
    - Spontaneous intestinal perforation (SIP) vs NEC   2
- Respiratory distress syndrome and chronic lung disease  

    - Apnea of prematurity   3
    - Bronchopulmonary dysplasia (BPD)   4
    - Oxygen toxicity and retinopathy of prematurity linkage   3
    - Surfactant biology and RDS management   3
    - Ventilation modes in NICU (conceptual)   3

###  Subspecialty Pediatrics 

   253 questions   

####  Advanced Cardiology 

   41   

  Complex congenital heart disease physiology, advanced arrhythmia management, cardiomyopathy, pulmona...

         - Advanced arrhythmia management  

    - Atrial flutter/fibrillation in children (overview)   3
    - Channelopathies and sudden cardiac death prevention   3
    - Pacemakers and ICDs (overview)   3
    - Wide complex tachycardia differential   2
    - WPW syndrome and pre-excitation   3
- Cardiomyopathy and myocarditis (advanced)  

    - Cardiac diagnostics interpretation (advanced)   3
    - Dilated cardiomyopathy evaluation   3
    - Hypertrophic cardiomyopathy (HCM) in youth   3
    - Myocarditis acute management and ECMO consideration   2
    - Pulmonary hypertension advanced overview   3
- Complex congenital heart disease physiology  

    - Coarctation and arch obstruction nuances   3
    - Endocarditis in congenital heart disease   2
    - Single ventricle palliation stages (conceptual)   3
    - Tetralogy of Fallot variants and spells   2
    - Transposition and mixing lesions management principles   3

####  Advanced Gastroenterology/Hepatology 

   139   

  IBD, chronic liver disease, complex abdominal pain, feeding disorders, pancreatic disease, and advan...

         - Chronic liver disease and portal hypertension  

    - Acute liver failure (advanced recognition)   3
    - Autoimmune hepatitis and PSC overview   4
    - Cholestatic disease (biliary atresia post-Kasai, PFIC overview)   4
    - Cirrhosis complications   4
    - Hepatitis B/C chronic infection management concepts   3
- Dermatology (advanced)  

    - Dermatologic manifestations of systemic disease   3
    - Genodermatoses and neurocutaneous disorders (selected)   4
    - Serious skin infections and toxin-mediated disease   3
    - Severe eczema and systemic therapies (overview)   3
    - Vascular tumors and malformations (advanced overview)   3
- Pancreatitis and biliary disorders  

    - Acute pancreatitis diagnosis and causes   4
    - Biliary dyskinesia and RUQ pain (overview)   3
    - Chronic pancreatitis (overview)   2
    - Management principles   3
    - Short bowel syndrome and intestinal failure (overview)   3
- Advanced Endocrinology  

    - Complex DKA and cerebral edema management   3
    - Disorders of puberty and DSD (advanced principles)   3
    - Endocrine hypertension and metabolic syndromes (overview)   3
    - Hypoglycemia workup with critical sample interpretation   2
    - Thyroid storm and adrenal crisis (advanced emergencies)   4
- Advanced Hematology/Oncology  

    - Complicated bleeding/thrombosis scenarios   3
    - Hemophagocytic lymphohistiocytosis (HLH) overview   3
    - Oncologic emergencies beyond TLS   3
    - Sickle cell complex management   3
    - Survivorship and late effects (overview)   4
- Advanced Nephrology/Urology  

    - CKD progression and complications management   4
    - Complex CAKUT and recurrent UTI management   2
    - Dialysis and transplant complications (overview)   4
    - Glomerular disease beyond basics (nephritic/nephrotic spectrum)   3
    - Hypertension with renal disease (advanced)   3
- Advanced Neurology  

    - Demyelinating disease in pediatrics (overview)   3
    - Epileptic encephalopathies and urgent syndromes   3
    - Headache complex cases and secondary causes (advanced)   3
    - Neuromuscular respiratory failure management (overview)   2
    - Status epilepticus refractory management (overview)   2
- Allergy/Immunology and Rheumatology (advanced)  

    - Complex JIA and biologic therapy monitoring   2
    - MIS-C and hyperinflammation (advanced overview)   4
    - Primary immunodeficiency detailed patterns (selected)   3
    - Severe drug reactions and allergy delabeling   4
    - Systemic vasculitides and connective tissue diseases (advanced overview)   3
- Inflammatory bowel disease (IBD) comprehensive overview  

    - Complications and emergencies   3
    - Crohn vs ulcerative colitis phenotypes   3
    - Initial evaluation and biomarkers   2
    - Nutrition and bone health in IBD   3
    - Therapy principles   3

####  Advanced Pulmonology/Sleep 

   59   

  Chronic lung disease, complex asthma, CF management, bronchiectasis, pulmonary hypertension, sleep m...

         - Bronchiectasis and chronic suppurative lung disease  

    - Aspiration and airway abnormalities   3
    - Complications and long-term follow-up   4
    - Etiologies and evaluation   3
    - Management strategies   3
    - Primary ciliary dyskinesia diagnostics (overview)   3
- Cystic fibrosis (CF) advanced management overview  

    - Airway clearance and chronic infection suppression   3
    - CF complications   3
    - CFTR modulators concept   3
    - Infection control and cross-infection prevention   2
    - Nutrition and pancreatic insufficiency management   3
- Severe asthma phenotypes and biologics (overview)  

    - Biologic therapies concept   3
    - Exercise-induced bronchoconstriction and differential   3
    - Phenotyping and modifiable risk factors   3
    - Severe exacerbation prevention strategies   3
    - Spirometry and bronchodilator response interpretation   3
- Sleep medicine (advanced)  

    - Behavioral sleep interventions for complex cases   2
    - Central sleep apnea and hypoventilation syndromes (overview)   3
    - Complex OSA and residual OSA post-tonsillectomy   2
    - Narcolepsy and hypersomnia (overview)   3
    - Periodic limb movement and restless legs in youth   4

####  Orthopedics/Sports Medicine (advanced) 

   14   

  Complex gait/hip disorders, sports cardiopulmonary clearance overlap, rehab, and imaging interpretat...

         - Complex hip disorders (Perthes, SCFE complications)  

    - Hip pain differential in athletes   3
    - Perthes disease staging concept   3
    - Rehabilitation and return-to-play decisions   2
    - SCFE complications and prevention   3
    - Sports-related sudden death screening overlap (overview)   3

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